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Results for “β-thalassemia”

118 trials

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Showing 20 of 118 results

Very early researchLooking for participantsNCT05745532
What this trial is testing

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

Who this might be right for
β-thalassemia
Shenzhen Hemogen 10
Testing effectiveness (Phase 2)Study completedNCT01044186
What this trial is testing

A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe Toxicity

Who this might be right for
Transfusional Iron Overload
Novartis Pharmaceuticals 30
Not applicableLooking for participantsNCT06734520
What this trial is testing

Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia

Who this might be right for
Thalassemia Majors (Beta-Thalassemia Major)Haplo-identical Donors
Guangzhou Women and Children's Medical Center 3
Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Not applicableStudy completedNCT01369719
What this trial is testing

Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload

Who this might be right for
ThalassemiaIron OverloadTransfusion Related Complications
Hormozgan University of Medical Sciences 138
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Not applicableTemporarily pausedNCT05442346
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
Thalassemia Major
Bioray Laboratories 5
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Not applicableStudy completedNCT04211480
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
β Thalassemia Major
Bioray Laboratories 6
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableStudy completedNCT01319552
What this trial is testing

Fresh Versus Old Red Blood Cells for Transfusion

Who this might be right for
Iron, Abnormal Blood LevelOther Abnormal Blood Chemistry
Columbia University 14
Not applicableEnded earlyNCT05752123
What this trial is testing

Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects with Transfusion Dependent Β-Thalassaemia.

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 2
Very early researchLooking for participantsNCT05864170
What this trial is testing

The Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
β-thalassemia
Shenzhen Hemogen 3
Testing effectiveness (Phase 2)Study completedNCT01745120
What this trial is testing

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

Who this might be right for
β-thalassemia Major
Genetix Biotherapeutics Inc. 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07489196
What this trial is testing

Safety and Efficacy Study Evaluating CS-101 in Participants With β-Thalassemia Major

Who this might be right for
β-thalassemia Major
CorrectSequence Therapeutics Co., Ltd 20
Not applicableEnrolling By InvitationNCT06363760
What this trial is testing

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Who this might be right for
Sickle Cell DiseaseTransfusion-dependent Beta-ThalassemiaHemoglobinopathies
Editas Medicine, Inc. 54
Not applicableLooking for participantsNCT06073860
What this trial is testing

A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia

Who this might be right for
Myelodysplastic SyndromeBeta Thalassemia
Bristol-Myers Squibb 104
Large-scale testing (Phase 3)Study completedNCT02604433
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia

Who this might be right for
Erythrocyte TransfusionBeta-Thalassemia
Celgene 336
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