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Results for “β-thalassemia”

114 trials

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Showing 20 of 114 results

Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Testing effectiveness (Phase 2)Study completedNCT00809042
What this trial is testing

Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia

Who this might be right for
β-Thalassemia Intermedia
Shiraz University of Medical Sciences 120
Testing effectiveness (Phase 2)Ended earlyNCT00586209
What this trial is testing

L-Glutamine Therapy for Sickle Cell Anemia

Who this might be right for
Sickle Cell AnemiaThalassemia
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 15
Very early researchUnknownNCT03728322
What this trial is testing

IHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia Mutations

Who this might be right for
Thalassemia
Allife Medical Science and Technology Co., Ltd. 12
Not applicableLooking for participantsNCT06219239
What this trial is testing

Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Institute of Hematology & Blood Diseases Hospital, China 3
Very early researchEnrolling By InvitationNCT06328764
What this trial is testing

CS-101 in Patients With β-thalassemia

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 10
Not applicableUnknownNCT00481221
What this trial is testing

Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter

Who this might be right for
ThalassemiaIron Deficiency
HaEmek Medical Center, Israel 30,000
Testing effectiveness (Phase 2)Looking for participantsNCT05693909
What this trial is testing

A Trial Testing SP-420 in Subjects With Transfusion-dependent β-thalassemia or Low-risk Myelodysplastic Syndromes

Who this might be right for
Beta Thalassemia Major AnemiaMyelodysplastic Syndrome
Pharmacosmos A/S 90
Testing effectiveness (Phase 2)Study completedNCT04364269
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia

Who this might be right for
Beta-ThalassemiaNon-transfusion-dependent Thalassemia
Vifor (International) Inc. 35
Testing effectiveness (Phase 2)Looking for participantsNCT07338344
What this trial is testing

Evaluating the Clinical Efficacy and Safety of Luspatercept Combined With Thalidomide in the Treatment of β-TDT Patients

Who this might be right for
Transfusion-dependent β-thalassemia Patients
Rongrong Liu 78
Not applicableEnrolling By InvitationNCT06717932
What this trial is testing

A Follow-up Study to Evaluate the Long-term Safety and Efficacy in Participants Who Received CS-101 Injection

Who this might be right for
Beta-Thalassemia
CorrectSequence Therapeutics Co., Ltd 8
Testing effectiveness (Phase 2)Looking for participantsNCT05736419
What this trial is testing

Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Who this might be right for
Sickle Cell DiseaseThalassemia, BetaThalassemia
Memorial Sloan Kettering Cancer Center 24
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Not applicableTemporarily pausedNCT05442346
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
Thalassemia Major
Bioray Laboratories 5
Very early researchLooking for participantsNCT05864170
What this trial is testing

The Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia

Who this might be right for
β-thalassemia
Shenzhen Hemogen 3
Not applicableStudy completedNCT02307786
What this trial is testing

Long Term Outcomes in β Thalassemia Major

Who this might be right for
Thalassemia Major
Ann & Robert H Lurie Children's Hospital of Chicago 176
Not applicableEnrolling By InvitationNCT06363760
What this trial is testing

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Who this might be right for
Sickle Cell DiseaseTransfusion-dependent Beta-ThalassemiaHemoglobinopathies
Editas Medicine, Inc. 54
Large-scale testing (Phase 3)Active Not RecruitingNCT04770779
What this trial is testing

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 258
Not applicableStudy completedNCT04211480
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
β Thalassemia Major
Bioray Laboratories 6
Not applicableStudy completedNCT04390971
What this trial is testing

Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
Institute of Hematology & Blood Diseases Hospital, China 3
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