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Results for “β-thalassemia Intermedia”

93 trials

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Showing 20 of 93 results

Very early researchLooking for participantsNCT05745532
What this trial is testing

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

Who this might be right for
β-thalassemia
Shenzhen Hemogen 10
Not applicableLooking for participantsNCT06734520
What this trial is testing

Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia

Who this might be right for
Thalassemia Majors (Beta-Thalassemia Major)Haplo-identical Donors
Guangzhou Women and Children's Medical Center 3
Early research (Phase 1)Ended earlyNCT04925206
What this trial is testing

A Safety and Efficacy Study Evaluating ET-01 in Subjects with Transfusion Dependent Β-Thalassaemia

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 8
Testing effectiveness (Phase 2)Looking for participantsNCT06280378
What this trial is testing

Β-Thalassemia Treatment with KL003 Cell Injection

Who this might be right for
Transfusion-dependent Beta-Thalassemia
Kanglin Biotechnology (Hangzhou) Co., Ltd. 41
Not applicableTemporarily pausedNCT05442346
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
Thalassemia Major
Bioray Laboratories 5
Early research (Phase 1)Ended earlyNCT02274233
What this trial is testing

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Who this might be right for
Iron OverloadBeta-Thalassemia
Sideris Pharmaceuticals 24
Not applicableLooking for participantsNCT05773729
What this trial is testing

Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia

Who this might be right for
β-thalassemia
Shanghai BDgene Co., Ltd. 10
Not applicableStudy completedNCT04211480
What this trial is testing

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Who this might be right for
β Thalassemia Major
Bioray Laboratories 6
Large-scale testing (Phase 3)Enrolling By InvitationNCT04208529
What this trial is testing

A Long-term Follow-up Study in Participants Who Received CTX001

Who this might be right for
Beta-ThalassemiaThalassemiaSickle Cell Disease+4 more
Vertex Pharmaceuticals Incorporated 160
Large-scale testing (Phase 3)Study completedNCT02906202
What this trial is testing

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Who this might be right for
Beta-Thalassemia
Genetix Biotherapeutics Inc. 24
Not applicableEnded earlyNCT05752123
What this trial is testing

Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects with Transfusion Dependent Β-Thalassaemia.

Who this might be right for
Transfusion Dependent Beta-Thalassaemia
EdiGene (GuangZhou) Inc. 2
Testing effectiveness (Phase 2)Study completedNCT01745120
What this trial is testing

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

Who this might be right for
β-thalassemia Major
Genetix Biotherapeutics Inc. 19
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07489196
What this trial is testing

Safety and Efficacy Study Evaluating CS-101 in Participants With β-Thalassemia Major

Who this might be right for
β-thalassemia Major
CorrectSequence Therapeutics Co., Ltd 20
Not applicableEnrolling By InvitationNCT06363760
What this trial is testing

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Who this might be right for
Sickle Cell DiseaseTransfusion-dependent Beta-ThalassemiaHemoglobinopathies
Editas Medicine, Inc. 54
Not applicableLooking for participantsNCT06073860
What this trial is testing

A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia

Who this might be right for
Myelodysplastic SyndromeBeta Thalassemia
Bristol-Myers Squibb 104
Large-scale testing (Phase 3)Study completedNCT02604433
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia

Who this might be right for
Erythrocyte TransfusionBeta-Thalassemia
Celgene 336
Testing effectiveness (Phase 2)Ended earlyNCT03993613
What this trial is testing

Apotransferrin in Patients With β-thalassemia

Who this might be right for
β-thalassemia Intermedia
Prothya Biosolutions 10
Large-scale testing (Phase 3)Looking for participantsNCT05477563
What this trial is testing

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Who this might be right for
Beta-ThalassemiaThalassemiaHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated 26
Not applicableUnknownNCT03101423
What this trial is testing

Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism

Who this might be right for
Beta Thalassemia Major
First Affiliated Hospital of Guangxi Medical University 30
Testing effectiveness (Phase 2)Study completedNCT04364269
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia

Who this might be right for
Beta-ThalassemiaNon-transfusion-dependent Thalassemia
Vifor (International) Inc. 35
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