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Results for “1st-line Treatment”

4,020 trials

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Showing 20 of 4,020 results

Post-approval studies (Phase 4)Looking for participantsNCT07546097
What this trial is testing

Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis（UPFRONT）

Who this might be right for
Acute Severe Ulcerative Colitis
Yongquan Shi 46
Not applicableStudy completedNCT03871088
What this trial is testing

N-3 Fatty Acids as the First-line Antidepressant Therapy: From Biomarkers to Clinical Subtypes

Who this might be right for
Major Depressive Disorder
National Science and Technology Council, Taiwan 400
Large-scale testing (Phase 3)Looking for participantsNCT06767527
What this trial is testing

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer (TNBC)
Akeso 416
Not applicableStudy completedNCT03602755
What this trial is testing

The First-line Treatment of Patients With Newly Diagnosed Transplant-ineligible Multiple Myeloma in Spain

Who this might be right for
Multiple Myeloma
Celgene 706
Large-scale testing (Phase 3)UnknownNCT02001896
What this trial is testing

Erlotinib Intercalated With Chemotherapy Versus Erlotinib as First Line Treatment in Stage IIIB/IV NSCLC Patients With EGFR Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Xinjiang Medical University 60
Post-approval studies (Phase 4)Study completedNCT04489888
What this trial is testing

Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Merck Sharp & Dohme LLC 101
Large-scale testing (Phase 3)Study completedNCT01505127
What this trial is testing

Efficacy of TAK-438, Amoxicillin and Clarithromycin in the First Line Eradication of H. Pylori

Who this might be right for
H. Pylori Infection
Takeda 650
Large-scale testing (Phase 3)Study completedNCT00095550
What this trial is testing

Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension

Who this might be right for
Hypertension
Bristol-Myers Squibb 496
Testing effectiveness (Phase 2)Study completedNCT04271813
What this trial is testing

Anlotinib Plus Sintilimab as First-line Treatment for Patients With Advanced Colorectal Cancer (APICAL-CRC)

Who this might be right for
Colorectal CancerImmunotherapyAnlotinib+3 more
Shanghai Changzheng Hospital 30
Testing effectiveness (Phase 2)UnknownNCT01097317
What this trial is testing

First-Line Chemotherapy With or Without Neuromuscular Electrical Stimulation in Treating Patients With Non-Small Cell Lung Cancer

Who this might be right for
Chemotherapeutic Agent ToxicityFatigueLung Cancer+1 more
Wales Cancer Trials Unit 52
Testing effectiveness (Phase 2)Study completedNCT00784446
What this trial is testing

First-line Therapy of Stage IV Colorectal Cancer

Who this might be right for
Stage IV Colorectal Cancer
University of Cologne 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05979220
What this trial is testing

Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy

Who this might be right for
Breast Cancer
Shuangyue Liu 178
Not applicableLooking for participantsNCT07024680
What this trial is testing

Real World Study of Effectiveness of Sunitinib or Sorafenib to Chinese Unresectable Locally Advanced or Metastatic PRCC

Who this might be right for
Papillary Renal Cell Carcinoma
AstraZeneca 150
Not applicableStudy completedNCT00724503
What this trial is testing

FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal CarcinomaLiver Metastases
Sirtex Medical 530
Testing effectiveness (Phase 2)Study completedNCT00609401
What this trial is testing

Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC)

Who this might be right for
Metastatic DiseaseRenal Cell Carcinoma
Italian Trial in Medical Oncology 90
Large-scale testing (Phase 3)Not Yet RecruitingNCT07318883
What this trial is testing

A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Advanced Squamous Non-Small Cell Lung Cancer

Who this might be right for
Squamous NSCLC
Shanghai Henlius Biotech 720
Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Testing effectiveness (Phase 2)Ended earlyNCT02196168
What this trial is testing

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Who this might be right for
Recurrent Hypopharyngeal Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell CarcinomaRecurrent Laryngeal Verrucous Carcinoma+26 more
National Cancer Institute (NCI) 6
Early research (Phase 1)Ended earlyNCT03395873
What this trial is testing

Avelumab With Decitabine as First Line for AML Treatment of Patients With AML, Who Are Unfit for Intensive Chemotherapy

Who this might be right for
Acute Myeloid Leukemia
Milton S. Hershey Medical Center 7
Large-scale testing (Phase 3)Ended earlyNCT02359162
What this trial is testing

Efficacy and Safety Study of P-Gemox vs.EPOCH as First-line Chemotherapy to Treat NK/T-cell Lymphoma With Early Stage

Who this might be right for
Lymphoma, Extranodal NK-T-Cell
Sun Yat-sen University 50
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