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Results for “AJCC Stage III/IV”

633 trials

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Showing 20 of 633 results

Early research (Phase 1)Study completedNCT03229278
What this trial is testing

Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma

Who this might be right for
LymphomaMetastatic Malignant Solid NeoplasmMetastatic Melanoma+26 more
Rutgers, The State University of New Jersey 14
Not applicableActive Not RecruitingNCT03731585
What this trial is testing

Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment

Who this might be right for
Non-Small Cell Lung CarcinomaStage I Lung Cancer AJCC v8Stage IA1 Lung Cancer AJCC v8+13 more
M.D. Anderson Cancer Center 70
Early research (Phase 1)Not Yet RecruitingNCT07716735
What this trial is testing

Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer

Who this might be right for
Advanced Kidney CarcinomaAdvanced Renal Cell CarcinomaHereditary Leiomyomatosis and Renal Cell Carcinoma+6 more
Jonsson Comprehensive Cancer Center 18
Testing effectiveness (Phase 2)Study completedNCT03179904
What this trial is testing

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

Who this might be right for
Advanced Breast CarcinomaHER2-Positive Breast CarcinomaAnatomic Stage III Breast Cancer AJCC v8+2 more
Mayo Clinic 17
Testing effectiveness (Phase 2)Active Not RecruitingNCT03008408
What this trial is testing

A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma

Who this might be right for
Recurrent Endometrial CarcinomaRecurrent Endometrial Endometrioid AdenocarcinomaRefractory Endometrial Carcinoma+10 more
M.D. Anderson Cancer Center 90
Early research (Phase 1)Looking for participantsNCT06696768
What this trial is testing

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage III Colorectal Cancer AJCC v8Stage IV Colorectal Cancer AJCC v8+1 more
National Cancer Institute (NCI) 24
Very early researchLooking for participantsNCT04005690
What this trial is testing

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Who this might be right for
Locally Advanced Pancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal AdenocarcinomaStage II Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute 90
Early research (Phase 1)Active Not RecruitingNCT02381561
What this trial is testing

Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

Who this might be right for
Advanced Bile Duct CarcinomaStage II Esophageal Cancer AJCC v7Stage II Pancreatic Cancer AJCC v6 and v7+38 more
National Cancer Institute (NCI) 19
Early research (Phase 1)Looking for participantsNCT07619313
What this trial is testing

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

Who this might be right for
Borderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced CholangiocarcinomaLocally Advanced Pancreatic Adenocarcinoma+5 more
Jonsson Comprehensive Cancer Center 46
Early research (Phase 1)Ended earlyNCT02097225
What this trial is testing

Onalespib, Dabrafenib, and Trametinib in Treating Patients With BRAF-Mutant Melanoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Malignant Solid Neoplasm+7 more
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Ended earlyNCT01413750
What this trial is testing

Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer

Who this might be right for
Stage IIIA Lung Non-Small Cell Cancer AJCC v7Stage IIIB Lung Non-Small Cell Cancer AJCC v7Stage IV Lung Non-Small Cell Cancer AJCC v7
National Cancer Institute (NCI) 23
Large-scale testing (Phase 3)Looking for participantsNCT06992427
What this trial is testing

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell CarcinomaStage I Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage II Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8+2 more
Alliance for Clinical Trials in Oncology
Testing effectiveness (Phase 2)WithdrawnNCT04119830
What this trial is testing

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaMicrosatellite StableMismatch Repair Proficient+10 more
Roswell Park Cancer Institute
Large-scale testing (Phase 3)Active Not RecruitingNCT03914612
What this trial is testing

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

Who this might be right for
Endometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated CarcinomaEndometrial Endometrioid Adenocarcinoma+13 more
National Cancer Institute (NCI) 813
Testing effectiveness (Phase 2)Study completedNCT02050919
What this trial is testing

Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma

Who this might be right for
Pleomorphic RhabdomyosarcomaStage IIB Adult Soft Tissue Sarcoma AJCC v7Stage III Adult Soft Tissue Sarcoma AJCC v7+1 more
OHSU Knight Cancer Institute 20
Testing effectiveness (Phase 2)Temporarily pausedNCT03384836
What this trial is testing

Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery

Who this might be right for
Stage IIIC Cutaneous Melanoma AJCC v7Stage IV Cutaneous Melanoma AJCC v6 and v7
Roswell Park Cancer Institute 47
Testing effectiveness (Phase 2)WithdrawnNCT05539365
What this trial is testing

Dendritic Cell-Based Treatment Plus Immunotherapy for the Treatment of Metastatic or Unresectable Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Looking for participantsNCT07012031
What this trial is testing

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Who this might be right for
Locally Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+1 more
National Cancer Institute (NCI) 37
Not applicableLooking for participantsNCT04723095
What this trial is testing

Establishing a Tumor Registry for Patients With Neuroendocrine Carcinoma of the Cervix

Who this might be right for
Cervical Large Cell Neuroendocrine CarcinomaCervical Neuroendocrine CarcinomaCervical Small Cell Carcinoma+19 more
M.D. Anderson Cancer Center 750
Large-scale testing (Phase 3)Looking for participantsNCT07383441
What this trial is testing

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

Who this might be right for
Advanced Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8+1 more
SWOG Cancer Research Network 718
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