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Results for “AK112”

81 trials

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Showing 20 of 81 results

Large-scale testing (Phase 3)Looking for participantsNCT06767527
What this trial is testing

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer (TNBC)
Akeso 416
Testing effectiveness (Phase 2)Looking for participantsNCT06769295
What this trial is testing

A Phase II Study of AK112 (PD1/VEGF Bispecific) in Combination with Chemotherapy in Patients with NSCLC

Who this might be right for
Lung Cancer, Non-Small Cell
Sichuan University 28
Testing effectiveness (Phase 2)Ended earlyNCT05636267
What this trial is testing

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

Who this might be right for
NSCLC
Akeso 59
Large-scale testing (Phase 3)Active Not RecruitingNCT06591520
What this trial is testing

AK112 Combined With Chemotherapy Versus Durvalumab Combined With Chemotherapy in Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Akeso 682
Testing effectiveness (Phase 2)Looking for participantsNCT06875076
What this trial is testing

Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural Mesothelioma

Who this might be right for
Pretreated Pleural Mesothelioma
The First Hospital of Jilin University 25
Testing effectiveness (Phase 2)Looking for participantsNCT06560112
What this trial is testing

An Exploratory, Multi-cohort Phase II Study of Combination Therapy With AK104 and AK112 for Recurrent Ovarian Cancer

Who this might be right for
Recurrent Ovarian Cancer
Akeso 172
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06593548
What this trial is testing

Lvosidenib (AK112) Combined With CapeOX and Radiotherapy in Patients With Unresectable Metastatic MSS-type Colorectal Cancer

Who this might be right for
CRCMSSMetastatic Cancer
Fudan University 36
Early research (Phase 1)Study completedNCT05116007
What this trial is testing

Anti-PD-1 and VEGF Bispecific Antibody AK112 in Combination With Chemotherapy in Patients With ES-SCLC

Who this might be right for
SCLC, Extensive Stage
Akeso 35
Testing effectiveness (Phase 2)Looking for participantsNCT06444009
What this trial is testing

A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Lei Liu 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07091227
What this trial is testing

Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Peking Union Medical College Hospital 66
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06904300
What this trial is testing

Ivonescimab (AK112) Plus Paclitaxel as Second-line Therapy in Patients With Advanced G/GEJ Cancer

Who this might be right for
Gastric (Cardia, Body) Cancer
Sun Yat-sen University 110
Testing effectiveness (Phase 2)Looking for participantsNCT07052253
What this trial is testing

A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.

Who this might be right for
Hepatocellular Carcinoma (HCC)
Akeso 100
Large-scale testing (Phase 3)Active Not RecruitingNCT05840016
What this trial is testing

AK112 in Combination With Chemotherapy in Advanced Squamous Non-Small Cell Lung Cancer

Who this might be right for
Advanced Squamous Non Small Cell Lung Cancer
Akeso 532
Testing effectiveness (Phase 2)Active Not RecruitingNCT06646055
What this trial is testing

AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Akeso 110
Testing effectiveness (Phase 2)Looking for participantsNCT07208773
What this trial is testing

YL201 and Ivonescimab (AK112) in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNon Small Cell Lung CancerSmall Cell Lung Cancer
MediLink Therapeutics (Suzhou) Co., Ltd. 260
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06478043
What this trial is testing

Investigate the Efficacy and Safety of Ivonescimab Combined With Irinotecan Liposome as Second-line Regimen for ES-SCLC

Who this might be right for
Extensive-stage Small-cell Lung Cancer
Zhejiang Cancer Hospital 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT05382442
What this trial is testing

AK112 With or Without AK117 in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Akeso 254
Testing effectiveness (Phase 2)Study completedNCT04900363
What this trial is testing

A Trial of AK112 (PD-1/VEGF Bispecific Antibody) in Patients With NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Akeso 108
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07357220
What this trial is testing

AK112 in Combination With VG2025 in Colorectal Cancer With Liver Metastases

Who this might be right for
Colorectal Cancer With Hepatic Metastases
Akeso 72
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07103447
What this trial is testing

Prospective Multicenter Single-arm Trial: AK112 + Nab-paclitaxel/Carboplatin Neoadjuvant for TNBC

Who this might be right for
Breast Cancer - Female
Shuangyue Liu 54
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