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Results for “AK112”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Looking for participantsNCT06791148
What this trial is testing

Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer

Who this might be right for
Gastric Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 45
Large-scale testing (Phase 3)Active Not RecruitingNCT06396065
What this trial is testing

Phase III Study of AK112 for NSCLC Patients

Who this might be right for
Non-Squamous Non-small Cell Lung Cancer
Summit Therapeutics 420
Testing effectiveness (Phase 2)UnknownNCT06375486
What this trial is testing

Ivonescimab Combined With HAIC for the Treatment of Unresectable Hepatocellular Carcinoma（uHCC）.

Who this might be right for
Hepatocellular Carcinoma Non-resectableHepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital 30
Testing effectiveness (Phase 2)Study completedNCT04900363
What this trial is testing

A Trial of AK112 (PD-1/VEGF Bispecific Antibody) in Patients With NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Akeso 108
Early research (Phase 1)Enrolling By InvitationNCT06424626
What this trial is testing

A Trial of AK104 or AK112 in Combination With Axitinib in Patients With Metastatic Mucosal Melanoma

Who this might be right for
MelanomaMucosal MelanomaMetastatic Melanoma
Peking University Cancer Hospital & Institute 60
Testing effectiveness (Phase 2)Ended earlyNCT04999605
What this trial is testing

AK112 Combined With PARP Inhibitor in the Treatment of Recurrent Ovarian Cancer

Who this might be right for
Ovarian NeoplasmsRecurrent Ovarian CarcinomaRelapsed Ovarian Cancer+1 more
Akeso 8
Testing effectiveness (Phase 2)Looking for participantsNCT07385001
What this trial is testing

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

Who this might be right for
Esophageal Squamous Cell CarcinomaIvonescimabNeoadjuvant
Tang-Du Hospital 45
Testing effectiveness (Phase 2)Looking for participantsNCT06686030
What this trial is testing

Combination Therapy of AK112 With Chemotherapy and/or Olaparib in Platinum-sensitive Ovarian Cancer

Who this might be right for
Platinum-sensitive Ovarian Cancer
Akeso 150
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07650838
What this trial is testing

OVV-01 Injection Combined With AK112 Injection for the Treatment of Patients With Advanced Soft Tissue Sarcoma (STS)

Who this might be right for
Soft Tissue Sarcoma (STS)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 40
Large-scale testing (Phase 3)Looking for participantsNCT06951503
What this trial is testing

AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer

Who this might be right for
Colorectal Adenocarcinoma
Akeso 560
Testing effectiveness (Phase 2)Looking for participantsNCT06875076
What this trial is testing

Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural Mesothelioma

Who this might be right for
Pretreated Pleural Mesothelioma
The First Hospital of Jilin University 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07091227
What this trial is testing

Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma

Who this might be right for
Gastric or Gastroesophageal Junction Adenocarcinoma
Peking Union Medical College Hospital 66
Testing effectiveness (Phase 2)Looking for participantsNCT07591090
What this trial is testing

A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
Akeso 200
Testing effectiveness (Phase 2)Looking for participantsNCT06530251
What this trial is testing

AK112 in Patients With Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Akeso 280
Testing effectiveness (Phase 2)Looking for participantsNCT07208773
What this trial is testing

YL201 and Ivonescimab (AK112) in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNon Small Cell Lung CancerSmall Cell Lung Cancer
MediLink Therapeutics (Suzhou) Co., Ltd. 260
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07630077
What this trial is testing

Trastuzumab Rezetecan(SHR-A1811) Combined With Ivonescimab (AK112) in Locally Advanced or Metastatic Non-small Cell Lung Cancer Harboring HER2 Gene Abnormalities

Who this might be right for
Non Small Cell Lung Cancer
Sun Yat-sen University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06472895
What this trial is testing

AK112 Monotherapy in Advanced/Metastatic Renal Cell Carcinoma

Who this might be right for
Renal Cell Carcinoma
Peking University Cancer Hospital & Institute 30
Testing effectiveness (Phase 2)Study completedNCT04597541
What this trial is testing

AK112 for Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
Akeso 59
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07488572
What this trial is testing

Safety and Efficacy of Yiwoxidan Anti (AK112) Monotherapy in Patients With Metastatic Renal Clear Cell Carcinoma Who Are Intolerant to TKI Treatment: a Prospective, Single Arm, Phase II Clinical Study

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Clear Cell Renal Cell Carcinoma
Sun Yat-sen University 60
Large-scale testing (Phase 3)Looking for participantsNCT07010263
What this trial is testing

AK112 as Consolidation Treatment for Patients With Limited Stage Small-cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation Therapy

Who this might be right for
Small Cell Lung Cancer
Akeso 560
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