Large-scale testing (Phase 3)Ended earlyNCT02489500What this trial is testingTrial of High Dose Melphalan/Stem Cell Transplant With or Without BortezomibWho this might be right forAL Amyloidosis Boston Medical Center 3
Early research (Phase 1)Study completedNCT02245867What this trial is testingStudy of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL AmyloidosisWho this might be right forAL Amyloidosis Alexion Pharmaceuticals, Inc. 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT06629818What this trial is testingDaratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14)Who this might be right forLight Chain (AL) Amyloidosis Peking Union Medical College Hospital 36
Early research (Phase 1)Study completedNCT01318902What this trial is testingStudy of Oral Ixazomib in Adult Participants With Relapsed or Refractory Light Chain AmyloidosisWho this might be right forLight-Chain Amyloidosis Millennium Pharmaceuticals, Inc. 27
Large-scale testing (Phase 3)Ended earlyNCT02312206What this trial is testingThe VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL AmyloidosisWho this might be right forPrimary Systemic (AL) Amyloidosis Prothena Biosciences Ltd. 260
Not applicableLooking for participantsNCT07215494What this trial is testingA Clinical Study on Minimal Residual Disease in Patients With Systemic Light Chain AmyloidosisWho this might be right forLight Chain (AL) AmyloidosisMRD Peking University First Hospital 50
Early research (Phase 1)Active Not RecruitingNCT02909036What this trial is testingStudy of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.Who this might be right forMultiple MyelomaAmyloidosis Memorial Sloan Kettering Cancer Center 46
Large-scale testing (Phase 3)Study completedNCT05184088What this trial is testingEfficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL AmyloidosisWho this might be right forCardiac AmyloidosisAL AmyloidosisATTR Amyloidosis Lantheus Germany GmbH 244
Early research (Phase 1)Active Not RecruitingNCT04847453What this trial is testingVenetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain AmyloidosisWho this might be right forRecurrent AL AmyloidosisRefractory AL Amyloidosis National Cancer Institute (NCI) 24
Not applicableStudy completedNCT02741999What this trial is testingA Diagnostic Screening Trial Seeking AL Amyloidosis Very EarlyWho this might be right forPlasma Cell DyscrasiaMonoclonal Gammopathy Tufts Medical Center 20
Not applicableEnrolling By InvitationNCT07103863What this trial is testingMultimodal Radiomics Model (18F-FAPI PET/CT + CMR) for AL Cardiac Amyloidosis PrognosisWho this might be right forAL Amyloidosis (AL)Cardiac Amyloidosis Beijing Anzhen Hospital 49
Testing effectiveness (Phase 2)Study completedNCT00458822What this trial is testingMelphalan and Autologous Stem Cell Transplant Followed By Bortezomib and Dexamethasone in Treating Patients With Previously Untreated Systemic AmyloidosisWho this might be right forMultiple Myeloma and Plasma Cell Neoplasm Memorial Sloan Kettering Cancer Center 40
Testing effectiveness (Phase 2)Study completedNCT04304144What this trial is testingEvaluate the Safety and Tolerability of CAEL-101 in Patients With AL AmyloidosisWho this might be right forAL Amyloidosis Alexion Pharmaceuticals, Inc. 25
Not applicableLooking for participantsNCT06192979What this trial is testingOptimize First-line Treatment for AL Amyloidosis With t (11; 14)Who this might be right forAmyloidosis; SystemicAL Amyloidosis Jin Lu, MD 41
Testing effectiveness (Phase 2)Ended earlyNCT02590588What this trial is testingIdelalisib for Immunoglobulin M (IgM)-Associated Primary (AL) AmyloidosisWho this might be right forAmyloidosis John Mark Sloan 1
Large-scale testing (Phase 3)Active Not RecruitingNCT04512235What this trial is testingEvaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)Who this might be right forAL Amyloidosis Alexion Pharmaceuticals, Inc. 281
Large-scale testing (Phase 3)Study completedNCT06788535What this trial is testingREVEAL - Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosisWho this might be right forCardiac Amyloidosis Sharmila Dorbala 204
Large-scale testing (Phase 3)UnknownNCT05776940What this trial is testingProbiotic Supplementation Reduces Gastrointestinal Symptoms During the Therapy and Improves Therapeutic Response in AL AmyloidosisWho this might be right forImmunoglobulin Light-chain Amyloidosis Air Force Military Medical University, China 116
Not applicableLooking for participantsNCT07448935What this trial is testingOne Gene, Two Diseases: the Pathologic Role of IGLV1-44 in AL Amyloidosis and POEMSWho this might be right forAL AmyloidosisPOEMS SyndromeMultiple Myeloma Fondazione IRCCS Policlinico San Matteo di Pavia 100
Testing effectiveness (Phase 2)Ended earlyNCT02994784What this trial is testingPropylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis PatientsWho this might be right forAmyloidosis; Systemic Boston Medical Center 27