Large-scale testing (Phase 3)Ended earlyNCT06111014What this trial is testingContinuation Study for LatozinemabWho this might be right forNeurodegenerative Diseases Alector Inc. 17
Not applicableLooking for participantsNCT06595212What this trial is testingGenetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics ApproachWho this might be right forALSFTD Azienda Ospedaliero-Universitaria di Modena 45
Not applicableEnrolling By InvitationNCT04961450What this trial is testingExplore Biomarkers of Motor Neuron Disease/Frontal Dementia Spectrum Disease in ChinaWho this might be right forAmyotrophic Lateral SclerosisFrontotemporal DementiaMotor Neuron Disease Peking University Third Hospital 2,500
Not applicableLooking for participantsNCT04363684What this trial is testingARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Who this might be right forFrontotemporal Lobar Degeneration (FTLD)Progressive Supranuclear Palsy (PSP)Corticobasal Degeneration (CBD)+11 more Mayo Clinic 2,100
Not applicableWithdrawnNCT04055532What this trial is testingBiomarkers in Neurodegenerative DiseasesWho this might be right forMild Cognitive Impairment (MCI)Alzheimer Disease (AD)Dementia With Lewy Bodies (DLB)+8 more University of Minnesota
Not applicableLooking for participantsNCT06528964What this trial is testingProteinopathies Expression in Skin of Neurodegenerative DisordersWho this might be right forAlzheimer DiseaseFrontotemporal DementiaParkinson Disease+3 more Universidad Autonoma de San Luis Potosí 40
Not applicableActive Not RecruitingNCT03912987What this trial is testingTRIAL READY (Clinical Trial Readiness)Who this might be right forAmyotrophic Lateral SclerosisFrontotemporal DementiaALS-Frontotemporal Dementia+2 more University of Miami 610
Not applicableStudy completedNCT05852405What this trial is testingClinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALSWho this might be right forMotor Neuron Disease, Amyotrophic Lateral Sclerosis Ambulanzpartner Soziotechnologie APST GmbH 2,000
Not applicableLooking for participantsNCT06377033What this trial is testingUsing the EHR to Advance Genomic Medicine Across a Diverse Health SystemWho this might be right forGenetic PredispositionParagangliomaPheochromocytoma+7 more University of Pennsylvania 1,000
Not applicableStudy completedNCT02365922What this trial is testingAdvancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)Who this might be right forFTLDProgressive Supranuclear Palsy (PSP)Frontotemporal Dementia (FTD)+9 more University of California, San Francisco 1,489
Testing effectiveness (Phase 2)Active Not RecruitingNCT04220021What this trial is testingSafety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTDWho this might be right forC9orf72 Amyotrophic Lateral Sclerosis (ALS)Frontotemporal Dementia University of Florida 41
Testing effectiveness (Phase 2)Study completedNCT05189106What this trial is testingNeurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialWho this might be right forAmyotrophic Lateral SclerosisAlzheimer DiseaseMild Cognitive Impairment Massachusetts General Hospital 17
Not applicableLooking for participantsNCT06803784What this trial is testingDiscovery and Validation of Protein Structural Complexes in Circulating Biofluids As Novel Biomarkers for Early Diagnosis, Prognosis and Therapeutic Management of Patients Affected by Neurodegenerative DisordersWho this might be right forParkinson DiseaseAmyotrophic Lateral Sclerosis (ALS)Frontotemporal Dementia (FTD)+1 more Neuromed IRCCS 110
Testing effectiveness (Phase 2)Ended earlyNCT04931862What this trial is testingStudy of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)Who this might be right forALSFTD Wave Life Sciences Ltd. 35
Not applicableLooking for participantsNCT04715399What this trial is testingUPenn Observational Research Repository on Neurodegenerative DiseaseWho this might be right forFrontotemporal Degeneration(FTD)Primary Progressive Aphasia(PPA)Familial Frontotemporal Lobar Degeneration (fFTLD)+6 more University of Pennsylvania 1,000
Not applicableLooking for participantsNCT06596746What this trial is testingNeurodegenerative Diseases Progression Markers (MARKERS-NDD)Who this might be right forNeurodegenerative DiseasesParkinson DiseaseSynucleinopathies+15 more Casa di Cura San Raffaele Cassino 600
Not applicableStudy completedNCT01925196What this trial is testingNatural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene MutationWho this might be right forAmyotrophic Lateral SclerosisFrontotemporal Lobar Degeneration National Institute of Neurological Disorders and Stroke (NINDS) 50
Not applicableLooking for participantsNCT00317616What this trial is testingThe Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) StudyWho this might be right forAmyotrophic Lateral Sclerosis University of Miami 500
Not applicableEnded earlyNCT00159198What this trial is testingAmyotrophic Lateral Sclerosis and Frontotemporal DementiaWho this might be right forFrontotemporal DementiaAmyotrophic Lateral Sclerosis Assistance Publique - Hôpitaux de Paris 400
Very early researchLooking for participantsNCT06891716What this trial is testing[18F]ACI-19626 PET in TDP-43 ProteinopathiesWho this might be right forFrontotemporal Dementia (FTD)Amyotrophic Lateral Sclerosis (ALS)TDP-43 Proteinopathies+2 more AC Immune SA 45