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Results for “AML and High Risk MDS”

436 trials

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Showing 20 of 436 results

Early research (Phase 1)Study completedNCT01149915
What this trial is testing

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+3 more
Threshold Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT00863148
What this trial is testing

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
MDSAMLALL+1 more
Nantes University Hospital 30
Testing effectiveness (Phase 2)Study completedNCT00003335
What this trial is testing

Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Case Comprehensive Cancer Center 44
Testing effectiveness (Phase 2)WithdrawnNCT04044209
What this trial is testing

The IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDS

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
Yale University
Testing effectiveness (Phase 2)Study completedNCT00065143
What this trial is testing

Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Who this might be right for
Leukemia, MyeloidMyelodysplastic Syndromes
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT01885689
What this trial is testing

Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia in Remission+4 more
City of Hope Medical Center
Early research (Phase 1)Study completedNCT02485535
What this trial is testing

Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

Who this might be right for
Acute Myeloid Leukemiade Novo Myelodysplastic SyndromeMyelodysplastic Syndrome+2 more
University of Chicago 12
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07562568
What this trial is testing

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMDS+4 more
The First Affiliated Hospital of Soochow University 160
Testing effectiveness (Phase 2)Study completedNCT00475150
What this trial is testing

Cediranib Maleate in Treating Patients With Relapsed, Refractory, or Untreated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+8 more
National Cancer Institute (NCI) 39
Early research (Phase 1)Ended earlyNCT00376519
What this trial is testing

Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+3 more
Masonic Cancer Center, University of Minnesota 3
Not applicableStudy completedNCT00296023
What this trial is testing

Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
University of California, San Francisco 25
Testing effectiveness (Phase 2)Study completedNCT00774046
What this trial is testing

High-dose Cytarabine/Mitoxantrone Followed by Autotransplantation for t-MDS/t-AML

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid Leukemia
University of Chicago 32
Testing effectiveness (Phase 2)Study completedNCT00045396
What this trial is testing

A Phase II Study Of The Farnesyltransferase Inhibitor ZANESTRA (R115777, NSC #702818, IND #58,359) In Complete Remission Following Induction And/Or Consolidation Chemotherapy In Adults With Poor-Risk Acute Myelogenous Leukemia (AML) And High-Risk Myelodysplasia (MDS)

Who this might be right for
Adult Acute Myeloid Leukemia in RemissionAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+6 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT02044796
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+3 more
Fred Hutchinson Cancer Center 199
Early research (Phase 1)Study completedNCT01629082
What this trial is testing

Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Who this might be right for
Myeldysplastic Syndrome (MDS)Chronic Myelomonocytic LeukemiaBone Marrow Diseases+2 more
National Heart, Lung, and Blood Institute (NHLBI) 4
Early research (Phase 1)Study completedNCT00875745
What this trial is testing

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Promyelocytic, AcuteMyelodysplastic Syndromes
Indiana University 15
Testing effectiveness (Phase 2)Ended earlyNCT02152956
What this trial is testing

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Who this might be right for
AML
MacroGenics 244
Testing effectiveness (Phase 2)Study completedNCT01101880
What this trial is testing

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+8 more
University of Washington 50
Very early researchUnknownNCT03795779
What this trial is testing

CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes+2 more
iCell Gene Therapeutics 20
Early research (Phase 1)Looking for participantsNCT03630991
What this trial is testing

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+15 more
M.D. Anderson Cancer Center 58
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