Not applicableLooking for participantsNCT07347925What this trial is testingEffect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEFWho this might be right forHeart Failure Future University in Egypt 140
Not applicableStudy completedNCT04498780What this trial is testingHemodynamic Effects of ARNI on Noninvasive Pressure-volume Analysis in Patients With Chronic Heart FailureWho this might be right forHeart Failure With Reduced Ejection Fraction University of Leipzig 117
Post-approval studies (Phase 4)Study completedNCT04023227What this trial is testingEfficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCCWho this might be right forChagas DiseaseHeart Failure Novartis Pharmaceuticals 922
Not applicableUnknownNCT05329727What this trial is testingThe Comparative Effectiveness Between ARNI and ACE Inhibitor/ARB Medication in Patient With HFrEFWho this might be right forHeart FailureMortality Wonju Severance Christian Hospital 1,000,000
Large-scale testing (Phase 3)UnknownNCT04912167What this trial is testingThe Effects of Sacubitril-Valsartan vs Enalapril on Left Ventricular Remodeling in ST-elevation Myocardial InfarctionWho this might be right forSTEMI West China Hospital 376
Testing effectiveness (Phase 2)Study completedNCT03744975What this trial is testingPDD in Type 2 Diabetes w/wo Diastolic DysfunctionWho this might be right forDiabetes Mellitus, Type 2Diastolic Dysfunction Mayo Clinic 72
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07261098What this trial is testingThe Efficacy and Safety of ARNI on the Outcome of Advanced Lung Cancer With Concurrent HypertensionWho this might be right forAdvanced Lung Cancer Shanghai Chest Hospital 200
Testing effectiveness (Phase 2)Study completedNCT01193101What this trial is testingEfficacy and Safety of LCZ696 Compared to Placebo in Patients With Essential HypertensionWho this might be right forHypertension Novartis Pharmaceuticals 389
Post-approval studies (Phase 4)Looking for participantsNCT07572032What this trial is testingDelayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot StudyWho this might be right forHeart Failure Due to Coronary Artery DiseaseValvular CardiomyopathyHeart Failure Kyungsub Song 80
Post-approval studies (Phase 4)Looking for participantsNCT07631156What this trial is testingSTEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart FailureWho this might be right forHeart Failure With Reduced Ejection FractionHeart FailureVentricular Dysfunction, Left Kyungsub Song 80
Testing effectiveness (Phase 2)Looking for participantsNCT06655480What this trial is testingTriple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEFWho this might be right forHFpEFLVDDMyocardial Fibrosis National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 50
Testing effectiveness (Phase 2)UnknownNCT04687111What this trial is testingPersonalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvationWho this might be right forAtrial RemodelingMyocardial DysfunctionLeft Ventricular Remodeling+6 more Mark Ledwidge 250
Not applicableStudy completedNCT05990296What this trial is testingEvaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure CareWho this might be right forHeart FailureHeart Failure With Reduced Ejection Fraction Geisinger Clinic 4,306
Not applicableUnknownNCT04107220What this trial is testingComparison of BNP and NT-proBNP in the Management of Patients With Chronic and Acute Heart FailureWho this might be right forHeart Failure Unity Health Toronto 300
Testing effectiveness (Phase 2)Study completedNCT01281306What this trial is testingAn 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic HypertensionWho this might be right forSystolic Hypertension Novartis Pharmaceuticals 910
Post-approval studies (Phase 4)UnknownNCT04929600What this trial is testingSacubitril/Valsartan Versus Amlodipine in Hypertension and Left Ventricular Hypertrophy.Who this might be right forHypertensionLeft Ventricular Hypertrophy Shanghai Jiao Tong University School of Medicine 120
Testing effectiveness (Phase 2)Study completedNCT04883528What this trial is testingProtecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019Who this might be right forCovid19 Duke University 42
Post-approval studies (Phase 4)UnknownNCT04342351What this trial is testingEarly Treatment of ARNI on Myocardial Remodeling and ProgressWho this might be right forMyocardial Infarction RenJi Hospital 280
Testing effectiveness (Phase 2)Study completedNCT03832660What this trial is testingSacubitril/Valsartan vs Lifestyle in Hypertrophic CardiomyopathyWho this might be right forHypertrophic Cardiomyopathy Newcastle University 168
Large-scale testing (Phase 3)Study completedNCT01615198What this trial is testingEfficacy and Safety of LCZ696 in Comparison to Olmesartan in Elderly Patients With Essential HypertensionWho this might be right forEssential Hypertension Novartis Pharmaceuticals 588