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Results for “ATTR Amyloidosis”

247 trials

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Showing 20 of 247 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06194825
What this trial is testing

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
AstraZeneca 64
Large-scale testing (Phase 3)Study completedNCT01994889
What this trial is testing

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 441
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Not applicableLooking for participantsNCT07196839
What this trial is testing

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
University of Texas Southwestern Medical Center 50
Testing effectiveness (Phase 2)Study completedNCT00694161
What this trial is testing

The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy

Who this might be right for
Cardiomyopathy
Pfizer 35
Testing effectiveness (Phase 2)Study completedNCT02595983
What this trial is testing

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Who this might be right for
Transthyretin (TTR)-Mediated AmyloidosisFamilial Amyloidotic Polyneuropathy (FAP)ATTR Amyloidosis+1 more
Alnylam Pharmaceuticals 12
Testing effectiveness (Phase 2)Study completedNCT05235269
What this trial is testing

Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic Amyloidosis

Who this might be right for
Amyloidosis
Attralus, Inc. 33
Not applicableLooking for participantsNCT04850105
What this trial is testing

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 240
Testing effectiveness (Phase 2)Active Not RecruitingNCT03536767
What this trial is testing

Open-Label Study of AG10 in Patients with Cardiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
Eidos Therapeutics, a BridgeBio company 55
Large-scale testing (Phase 3)Active Not RecruitingNCT04136171
What this trial is testing

CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)

Who this might be right for
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
Ionis Pharmaceuticals, Inc. 1,438
Not applicableUnknownNCT05087953
What this trial is testing

Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease

Who this might be right for
Autonomic Nervous System DiseaseAmyloid Neuropathies
University of Sao Paulo General Hospital 60
Not applicableLooking for participantsNCT07644325
What this trial is testing

Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy

Who this might be right for
Carpal TunnelTransthyretin Amyloidosis
Clinique Saint Jean, France 500
Large-scale testing (Phase 3)Active Not RecruitingNCT06183931
What this trial is testing

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
Alexion Pharmaceuticals, Inc. 1,181
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableUnknownNCT05196594
What this trial is testing

Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis

Who this might be right for
Amyloidosis, Hereditary, Transthyretin-RelatedMicrobial Colonization
University of Sao Paulo General Hospital 60
Not applicableActive Not RecruitingNCT04801329
What this trial is testing

Korean Post-marketing Surveillance Vyndamax® Capsules for the Treatment of Transthyretin Amyloid Cardiomyopathy

Who this might be right for
ATTR-CM (Transthyretin Amyloid Cardiomyopathy)
Pfizer 110
Testing effectiveness (Phase 2)Study completedNCT01171859
What this trial is testing

Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 40
Not applicableNot Yet RecruitingNCT07398950
What this trial is testing

Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Who this might be right for
ATTR Amyloidosis With CardiomyopathyHeart Failure
Yale University 150
Large-scale testing (Phase 3)Study completedNCT05184088
What this trial is testing

Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis

Who this might be right for
Cardiac AmyloidosisAL AmyloidosisATTR Amyloidosis
Lantheus Germany GmbH 244
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
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