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Results for “ATYPICAL HEMOLYTIC UREMIC SYNDROME (AHUS)”

47 trials

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Showing 20 of 47 results

Not applicableStudy completedNCT01755429
What this trial is testing

To Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS Patients

Who this might be right for
ATYPICAL HEMOLYTIC UREMIC SYNDROME (AHUS)
Alexion Pharmaceuticals, Inc. 2
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)Study completedNCT03518203
What this trial is testing

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Who this might be right for
Thrombotic MicroangiopathiesAtypical Hemolytic Uremic SyndromeMultiple Organ Dysfunction Syndrome
Children's Hospital Medical Center, Cincinnati 23
Large-scale testing (Phase 3)Active Not RecruitingNCT04861259
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Hoffmann-La Roche 83
Not applicableEnded earlyNCT01522170
What this trial is testing

AHUS Observational Long Term Follow-Up

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 94
Post-approval studies (Phase 4)Looking for participantsNCT07308574
What this trial is testing

Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS

Who this might be right for
aHUSAtypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 20
Not applicableLooking for participantsNCT01522183
What this trial is testing

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 3,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05684159
What this trial is testing

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

Who this might be right for
aHUS - Atypical Hemolytic Uremic Syndrome
NovelMed Therapeutics 12
Not applicableLooking for participantsNCT06312644
What this trial is testing

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Who this might be right for
Ultomiris-exposed Pregnant/ PostpartumPregnancyParoxysmal Nocturnal Hemoglobinuria (PNH)+3 more
Alexion Pharmaceuticals, Inc. 75
Not applicableActive Not RecruitingNCT06099236
What this trial is testing

A Prospective, Non-interventional, Observational Study of Presentation, Treatment Patterns and Outcomes in Atypical Hemolytic Uremic Syndrome Patients

Who this might be right for
Atypical Hemolytic Uremic Syndrome(aHUS)
AstraZeneca 367
Testing effectiveness (Phase 2)WithdrawnNCT03999840
What this trial is testing

Eculizumab to Cemdisiran Switch in aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research
Not applicableNot Yet RecruitingNCT07399730
What this trial is testing

Ravulizumab Outcomes in Polish Patients With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
AstraZeneca 80
Not applicableUnknownNCT03574506
What this trial is testing

Eculizumab Use in the Postpartum Period for the Treatment of Pregnancy Associated aHUS: A Case Series

Who this might be right for
Atypical Hemolytic Uremic SyndromePregnancy
Fundación Grupo de Investigación en Cuidados Intensivos y Obstetricia 50
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Testing effectiveness (Phase 2)Study completedNCT01757431
What this trial is testing

The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 2
Not applicableStudy completedNCT05405777
What this trial is testing

A Retrospective Study to Evaluate the Clinical Outcome According to Treatment in aHUS Patients in South Korea

Who this might be right for
aHUS
Handok Inc. 97
Not applicableLooking for participantsNCT05996731
What this trial is testing

Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases

Who this might be right for
Atypical Hemolytic Uremic SyndromeMembranoproliferative GlomerulonephritisAutosomal Dominant Polycystic Kidney+1 more
Mario Negri Institute for Pharmacological Research 105
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Testing effectiveness (Phase 2)Ended earlyNCT02464891
What this trial is testing

Complement Inhibition in aHUS Dialysis Patients

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 6
Testing effectiveness (Phase 2)Study completedNCT00844844
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 1
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