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Results for “Abemaciclib”

188 trials

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Showing 20 of 188 results

Very early researchStudy completedNCT04049227
What this trial is testing

Abemaciclib and Letrozole in Treating Patients With Endometrial Cancer

Who this might be right for
Endometrial Endometrioid Adenocarcinoma
Northwestern University 27
Testing effectiveness (Phase 2)Study completedNCT04921904
What this trial is testing

Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca

Who this might be right for
Metastatic Esophageal AdenocarcinomaMetastatic Gastroesophageal Junction Adenocarcinoma
Baylor Research Institute 26
Early research (Phase 1)Looking for participantsNCT05714072
What this trial is testing

Ruxolitinib in Combination With Abemaciclib for the Treatment of Myelofibrosis

Who this might be right for
Myelofibrosis Due to and Following Polycythemia Vera
Memorial Sloan Kettering Cancer Center 18
Testing effectiveness (Phase 2)Ended earlyNCT03655444
What this trial is testing

Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Washington University School of Medicine 6
Testing effectiveness (Phase 2)Ended earlyNCT03130439
What this trial is testing

Abemaciclib for Patients With Retinoblastoma-Positive, Triple Negative Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Dana-Farber Cancer Institute 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT04293393
What this trial is testing

Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients

Who this might be right for
Early Breast Cancer
Spanish Breast Cancer Research Group 200
Testing effectiveness (Phase 2)WithdrawnNCT04118036
What this trial is testing

Abemaciclib + Pembrolizumab In Glioblastoma

Who this might be right for
Glioblastoma
Dana-Farber Cancer Institute
Not applicableLooking for participantsNCT07214532
What this trial is testing

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Who this might be right for
Breast NeoplasmsCarcinoma, Ductal, BreastReceptors, Estrogen (for ER-positive Requirement)
Natera, Inc. 725
Not applicableUnknownNCT06344780
What this trial is testing

Abemaciclib, Palbociclib or Dalpiciclib Combined with Endocrine Therapy As First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Fudan University 200
Not applicableStudy completedNCT05598788
What this trial is testing

Microsampling Approach for Monitoring of Kinase Inhibitor Targeted Therapies

Who this might be right for
Blood Concentrations of Nine Anti-cancer Drugs : Axitinib, Olaparib, regorafénib, Cabozantinib, Niraparib, Talazoparib, Palbociclib, Abemaciclib, Tucatinib
Rennes University Hospital 160
Testing effectiveness (Phase 2)Looking for participantsNCT02523014
What this trial is testing

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Who this might be right for
Intracranial MeningiomaRecurrent MeningiomaNF2 Gene Mutation
Alliance for Clinical Trials in Oncology 124
Testing effectiveness (Phase 2)Ended earlyNCT04169074
What this trial is testing

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

Who this might be right for
HNSCC
University of Arizona 7
Testing effectiveness (Phase 2)Looking for participantsNCT04941274
What this trial is testing

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Who this might be right for
Kaposi Sarcoma
National Cancer Institute (NCI) 111
Post-approval studies (Phase 4)Study completedNCT04707196
What this trial is testing

Abemaciclib in Indian Women With Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasm Metastasis
Eli Lilly and Company 200
Testing effectiveness (Phase 2)Looking for participantsNCT07100106
What this trial is testing

Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

Who this might be right for
Breast Cancer
Genentech, Inc. 285
Not applicableApproved For MarketingNCT03763604
What this trial is testing

Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Eli Lilly and Company
Post-approval studies (Phase 4)Looking for participantsNCT06169371
What this trial is testing

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

Who this might be right for
Breast Cancer
University of Illinois at Chicago 50
Large-scale testing (Phase 3)Active Not RecruitingNCT04967521
What this trial is testing

SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

Who this might be right for
Advanced Dedifferentiated Liposarcoma
Sarcoma Alliance for Research through Collaboration 108
Testing effectiveness (Phase 2)Ended earlyNCT04534283
What this trial is testing

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

Who this might be right for
CancerCancer MetastaticBRAF V600E+4 more
Anita Turk 16
Early research (Phase 1)Study completedNCT02688088
What this trial is testing

Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body

Who this might be right for
Neoplasm Metastasis
Eli Lilly and Company 48
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