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Results for “Acidemias”

61 trials

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Showing 20 of 61 results

Not applicableStudy completedNCT00004353
What this trial is testing

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

Who this might be right for
Mitochondrial MyopathyMELAS SyndromeLactic Acidosis
National Center for Research Resources (NCRR) 35
Not applicableLooking for participantsNCT02890342
What this trial is testing

Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

Who this might be right for
Metabolic DiseasePropionic AcidemiaOrganic Acidemia
National Human Genome Research Institute (NHGRI) 1,045
Not applicableStudy completedNCT05772988
What this trial is testing

Beta-alanine Supplementation and CrossFit Performance

Who this might be right for
Exercise-Induced Lactic Acidemia
University of Saskatchewan 12
Not applicableEnrolling By InvitationNCT06953505
What this trial is testing

At Home Ammonia Monitoring of Inborn Errors of Ammonia Metabolism

Who this might be right for
Urea Cycle DisordersOrganic AcidemiasFatty Acid Oxidation Disorder+1 more
Sequitur Health Corp. 30
Not applicableStudy completedNCT03917212
What this trial is testing

Energy Metabolism in Branched-chain Organic Acidemias

Who this might be right for
Energy MetabolismMetabolic SyndromeInsulin Resistance
German Diabetes Center 57
Not applicableLooking for participantsNCT07333599
What this trial is testing

Hypoxia Profiles Identified in Term Newborns With Cord pH <7.00

Who this might be right for
Neonatal Acidemia and Hypoxia
University Hospital, Strasbourg, France 400
Testing effectiveness (Phase 2)Ended earlyNCT04732429
What this trial is testing

Study of HST5040 in Subjects With Propionic or Methylmalonic Acidemia

Who this might be right for
Methylmalonic AcidemiaPropionic Acidemia
HemoShear Therapeutics 26
Early research (Phase 1)Study completedNCT02363829
What this trial is testing

Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)

Who this might be right for
Uterine Cervix Cancer
Abramson Cancer Center at Penn Medicine 6
Testing effectiveness (Phase 2)Ended earlyNCT01597440
What this trial is testing

Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia

Who this might be right for
Propionic AcidemiaMethylmalonic Acidemia
Mendel Tuchman 1
Early research (Phase 1)Looking for participantsNCT06217861
What this trial is testing

Evaluate the Tolerability, Safety and Efficacy of VGM-R02b

Who this might be right for
Glutaric Acidemia Type IGlutaric Aciduria Type I
Shanghai Vitalgen BioPharma Co., Ltd. 12
Testing effectiveness (Phase 2)Study completedNCT01793090
What this trial is testing

EPI-743 in Cobalamin C Defect: Effects on Visual and Neurological Impairment

Who this might be right for
Methylmalonic Aciduria and Homocystinuria,Cblc TypeGenetic DiseaseRetinopathy
Bambino Gesù Hospital and Research Institute 30
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Large-scale testing (Phase 3)Study completedNCT02426775
What this trial is testing

Carglumic Acid in Methylmalonic Acidemia and Propionic Acidemia

Who this might be right for
Propionic AcidemiaMethylmalonic Acidemia
King Abdullah International Medical Research Center 33
Testing effectiveness (Phase 2)WithdrawnNCT03810690
What this trial is testing

Open Label Study of mRNA-3704 in Patients With Isolated Methylmalonic Acidemia

Who this might be right for
Methylmalonic Acidemia (MMA)Metabolism, Inborn Errors
ModernaTX, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT04899310
What this trial is testing

Assess the Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia

Who this might be right for
Methylmalonic Acidemia
ModernaTX, Inc. 74
Not applicableNot Yet RecruitingNCT06664840
What this trial is testing

MyRareDiet A Novel Diet Tracking Tool

Who this might be right for
Urea Cycle DisorderPropionic AciduriaMaple Syrup Urine Disease+1 more
Oregon Health and Science University 60
Not applicableStudy completedNCT04284917
What this trial is testing

Long-term Efficacy of Carglumic Acid in Organic Acidemia.

Who this might be right for
Propionic Acidemia (PA) , Methylmalonic Acidemia (MMA)
National Taiwan University Hospital 3
Not applicableUnknownNCT01289158
What this trial is testing

Combined Malonic and Methylmalonic Aciduria (CMAMMA): Gene Identification and Outcome Study

Who this might be right for
Malonic AciduriaMethylmalonic Acidemia
McGill University Health Centre/Research Institute of the McGill University Health Centre 6
Testing effectiveness (Phase 2)Ended earlyNCT04581785
What this trial is testing

Gene Therapy With hLB-001 in Pediatric Patients With Severe Methylmalonic Acidemia

Who this might be right for
Methylmalonic Acidemia
LogicBio Therapeutics, Inc 4
Testing effectiveness (Phase 2)Looking for participantsNCT05130437
What this trial is testing

Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study

Who this might be right for
Propionic Acidemia
ModernaTX, Inc. 50
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