Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Active Moderate to Severe Rheumatoid Arthritis”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Ended earlyNCT03970837
What this trial is testing

Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 1,764
Testing effectiveness (Phase 2)Study completedNCT04247815
What this trial is testing

Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA

Who this might be right for
Rheumatoid Arthritis
Aclaris Therapeutics, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT02969044
What this trial is testing

Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate

Who this might be right for
Rheumatoid Arthritis
Pfizer 70
Large-scale testing (Phase 3)Study completedNCT02480153
What this trial is testing

PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02).

Who this might be right for
Rheumatoid Arthritis
Pfizer 597
Post-approval studies (Phase 4)UnknownNCT05803135
What this trial is testing

Iguratimod Combined With Tofacitinib in the Treatment of Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Nanfang Hospital, Southern Medical University 138
Large-scale testing (Phase 3)Study completedNCT04230213
What this trial is testing

A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Pfizer 455
Large-scale testing (Phase 3)Study completedNCT00109408
What this trial is testing

Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 673
Large-scale testing (Phase 3)Ended earlyNCT01682512
What this trial is testing

Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
Boehringer Ingelheim 294
Testing effectiveness (Phase 2)Study completedNCT03254966
What this trial is testing

Study of SHR0302 Tablets (SHR0302) as Monotherapy in Active Rheumatoid Arthritis (RA) Patients

Who this might be right for
Rheumatoid Arthritis
Jiangsu HengRui Medicine Co., Ltd. 194
Testing effectiveness (Phase 2)Study completedNCT06565273
What this trial is testing

Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd 40
Very early researchNot Yet RecruitingNCT06982547
What this trial is testing

Clinical Study on the Treatment of Refractory Rheumatoid Arthritis With UTAA91 Injection

Who this might be right for
Rheumatoid Arthritis (RA)
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 24
Not applicableStudy completedNCT01362062
What this trial is testing

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 110
Testing effectiveness (Phase 2)Study completedNCT01468077
What this trial is testing

A Study in Patients With Moderate to Severe Active Rheumatoid Arthritis Comparing Different Infusion Durations of RoActemra/Actemra (Tocilizumab) Treatment

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 47
Large-scale testing (Phase 3)Study completedNCT02706951
What this trial is testing

A Study Comparing Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to MTX (SELECT-MONOTHERAPY)

Who this might be right for
Rheumatoid Arthritis
AbbVie 648
Large-scale testing (Phase 3)Study completedNCT06104124
What this trial is testing

Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity

Who this might be right for
Sjogren's Syndrome
Amgen 651
Post-approval studies (Phase 4)Study completedNCT01185288
What this trial is testing

Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA)

Who this might be right for
Rheumatoid Arthritis
AbbVie (prior sponsor, Abbott) 309
Large-scale testing (Phase 3)Study completedNCT00848120
What this trial is testing

Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 29
Not applicableLooking for participantsNCT04876781
What this trial is testing

Korean Post-marketing Surveillance for Xeljanz XR

Who this might be right for
Active Moderate to Severe Rheumatoid ArthritisActive Ankylosing SpondylitisActive Psoriatic Arthritis
Pfizer 200
Large-scale testing (Phase 3)Study completedNCT02886728
What this trial is testing

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy

Who this might be right for
Rheumatoid Arthritis
Gilead Sciences 1,252
Large-scale testing (Phase 3)Study completedNCT01194414
What this trial is testing

Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 1,262
Next Page