Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Active Secondary Progressive Multiple Sclerosis”

27 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 27 results

Post-approval studies (Phase 4)Active Not RecruitingNCT05090371
What this trial is testing

Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

Who this might be right for
Relapsing-Remitting Multiple Sclerosis
Novartis Pharmaceuticals 136
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 32
Large-scale testing (Phase 3)Active Not RecruitingNCT05441488
What this trial is testing

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis

Who this might be right for
Progressive Multiple Sclerosis
AB Science 800
Large-scale testing (Phase 3)Active Not RecruitingNCT05156281
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,011
Large-scale testing (Phase 3)Ended earlyNCT04925557
What this trial is testing

Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary-progressive Multiple Sclerosis
State University of New York at Buffalo 8
Not applicableAvailableNCT06802328
What this trial is testing

Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients

Who this might be right for
Non-Active Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD
Testing effectiveness (Phase 2)Looking for participantsNCT06292923
What this trial is testing

Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Who this might be right for
Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD 54
Testing effectiveness (Phase 2)Study completedNCT01450488
What this trial is testing

Masitinib in Primary Progressive Multiple Sclerosis or Relapse-free Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AB Science 35
Not applicableNo Longer AvailableNCT04540861
What this trial is testing

Managed Access Program (MAP) for Patients Diagnosed With Secondary Progressive Multiple Sclerosis With Active Disease

Who this might be right for
Multiple Sclerosis
Novartis Pharmaceuticals
Not applicableStudy completedNCT05376579
What this trial is testing

Impact of Mayzent on aSPMS Patients in a Long-term NIS in Italy

Who this might be right for
Active Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 134
Early research (Phase 1)Temporarily pausedNCT06677710
What this trial is testing

IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple Sclerosis (PPMS)Secondary Progressive Multiple Sclerosis (SPMS)+8 more
Indapta Therapeutics, INC. 34
Not applicableStudy completedNCT06436131
What this trial is testing

The Effects of In-phase Bilateral Exercise in People with Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary ProgressiveMultiple Sclerosis, Secondary Progressive
Cyprus University of Technology 20
Testing effectiveness (Phase 2)Study completedNCT01982942
What this trial is testing

Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Primary ProgressiveMultiple Sclerosis, Secondary Progressive
MediciNova 255
Not applicableUnknownNCT05385731
What this trial is testing

MUSCLE - Nordic Walking in MUltiple SCLErosis

Who this might be right for
Multiple Sclerosis, Chronic ProgressiveMultiple SclerosisMultiple Sclerosis, Primary Progressive+1 more
Leonardo A. Peyré-Tartaruga 60
Large-scale testing (Phase 3)Study completedNCT03315923
What this trial is testing

Comparison of Clinical Effects of Rituximab and Glatiramer Acetate in Secondary Progressive Multiple Sclerosis Patients

Who this might be right for
Secondary Progressive Multiple Sclerosis
Isfahan University of Medical Sciences 84
Large-scale testing (Phase 3)Active Not RecruitingNCT04688788
What this trial is testing

Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis

Who this might be right for
Relapsing Remitting Multiple SclerosisSecondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
Rigshospitalet, Denmark 600
Large-scale testing (Phase 3)Active Not RecruitingNCT05147220
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,001
Not applicableEnded earlyNCT04746976
What this trial is testing

Study of Diroximel Fumarate in the Real-World Setting

Who this might be right for
Relapsing Forms of MS
Biogen 75
Testing effectiveness (Phase 2)Looking for participantsNCT06890923
What this trial is testing

Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis

Who this might be right for
Non-Active Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD 55
Not applicableEnded earlyNCT04948606
What this trial is testing

Exploring Diroximel Fumarate Real-world Experience in Canada and Israel

Who this might be right for
Relapsing Forms of MS
Biogen 64
Load More Results