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Results for “Acute Intermittent Porphyria (AIP)”

22 trials

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Showing 20 of 22 results

Testing effectiveness (Phase 2)Ended earlyNCT02922413
What this trial is testing

Panhematin for Prevention of Acute Attacks of Porphyria

Who this might be right for
Acute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria
The University of Texas Medical Branch, Galveston 13
Early research (Phase 1)Study completedNCT02452372
What this trial is testing

Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Who this might be right for
Acute Intermittent Porphyria
Alnylam Pharmaceuticals 40
Testing effectiveness (Phase 2)Study completedNCT00004789
What this trial is testing

Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria

Who this might be right for
Porphyria
National Center for Research Resources (NCRR) 59
Not applicableApproved For MarketingNCT04056481
What this trial is testing

Expanded Access Protocol of Givosiran for Patients With Acute Hepatic Porphyria

Who this might be right for
Acute Hepatic Porphyria
Alnylam Pharmaceuticals
Not applicableStudy completedNCT05882136
What this trial is testing

Acute Intermittent Porphyria Related Abnormalities in Cardiovascular System

Who this might be right for
Porphyrias, Hepatic
National Institute of Cardiology, Warsaw, Poland 180
Testing effectiveness (Phase 2)Study completedNCT00004396
What this trial is testing

Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias

Who this might be right for
Porphyria
National Center for Research Resources (NCRR) 32
Not applicableLooking for participantsNCT05502133
What this trial is testing

Identification of Acute Intermittent Porphyria Modifying Genes

Who this might be right for
Acute Intermittent Porphyria (AIP)
Icahn School of Medicine at Mount Sinai 150
Not applicableLooking for participantsNCT01561157
What this trial is testing

Longitudinal Study of the Porphyrias

Who this might be right for
Acute PorphyriasCutaneous Porphyrias
Icahn School of Medicine at Mount Sinai 1,500
Large-scale testing (Phase 3)Study completedNCT03338816
What this trial is testing

ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)

Who this might be right for
Acute Hepatic PorphyriaAcute Intermittent PorphyriaPorphyria, Acute Intermittent+4 more
Alnylam Pharmaceuticals 94
Large-scale testing (Phase 3)Study completedNCT00418795
What this trial is testing

Porphozym in the Treatment of Acute Attacks in AIP

Who this might be right for
Acute Intermittent Porphyria
Zymenex A/S 36
Early research (Phase 1)Study completedNCT02943213
What this trial is testing

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Who this might be right for
Anti-PsychoticManagement of Manifestations of Psychotic DisordersTreatment of Schizophrenia+6 more
Cycle Pharmaceuticals Ltd. 20
Not applicableLooking for participantsNCT06273644
What this trial is testing

Clinical Research on Acute Intermittent Porphyria and the Use of Carbohydrate-Rich Diet as a Treatment

Who this might be right for
Porphyria, Acute Intermittent
Nordlandssykehuset HF 50
Early research (Phase 1)Study completedNCT03505853
What this trial is testing

Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP)

Who this might be right for
Acute Intermittent Porphyria (AIP)Acute Hepatic Porphyria (AHP)Porphyria, Acute Intermittent+1 more
Alnylam Pharmaceuticals 10
Not applicableStudy completedNCT03906214
What this trial is testing

Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria

Who this might be right for
Porphyrias
University of South Florida 60
Testing effectiveness (Phase 2)Study completedNCT02180412
What this trial is testing

Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria

Who this might be right for
Acute Porphyrias
The University of Texas Medical Branch, Galveston 20
Not applicableStudy completedNCT02076763
What this trial is testing

Observational Study of Acute Intermittent Porphyria Patients

Who this might be right for
Acute Intermittent Porphyria
Digna Biotech S.L. 9
Not applicableActive Not RecruitingNCT02935400
What this trial is testing

Acute Porphyria Biomarkers for Disease Activity

Who this might be right for
Acute Intermittent PorphyriaHereditary CoproporphyriaVariegate Porphyria
The University of Texas Medical Branch, Galveston 50
Not applicableStudy completedNCT01568554
What this trial is testing

Clinical Diagnosis of Acute Porphyria

Who this might be right for
Hereditary Coproporphyria (HCP)Acute Intermittent Porphyria (AIP)Variegate Porphyria (VP)
University of California, San Francisco 148
Testing effectiveness (Phase 2)Study completedNCT02949830
What this trial is testing

Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)

Who this might be right for
Acute Intermittent Porphyria
Alnylam Pharmaceuticals 16
Early research (Phase 1)Study completedNCT02082860
What this trial is testing

Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria

Who this might be right for
Acute Intermittent Porphyria
Digna Biotech S.L. 8
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