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Results for “Acute Lymphoblastic Leukemia, High Risk”

326 trials

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Showing 20 of 326 results

Not applicableLooking for participantsNCT06710418
What this trial is testing

Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemia

Who this might be right for
Acute Myeloid LeukemiaB Acute Lymphoblastic LeukemiaB Lymphoblastic Lymphoma+1 more
University of Washington 50
Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Early research (Phase 1)Looking for participantsNCT07573111
What this trial is testing

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute LeukemiaMyelodysplastic Syndrome
Laguna Biotherapeutics, Inc. 12
Early research (Phase 1)Study completedNCT03263637
What this trial is testing

Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

Who this might be right for
Relapsed or Refractory Haematological Malignancies IncludingAcute Myeloid LeukemiaAcute Lymphocytic Leukemia+8 more
AstraZeneca 44
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Testing effectiveness (Phase 2)Active Not RecruitingNCT03709719
What this trial is testing

Blinatumomab in High-risk B-cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, Adult B-Cell
Assistance Publique - Hôpitaux de Paris 95
Testing effectiveness (Phase 2)Looking for participantsNCT05735717
What this trial is testing

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Who this might be right for
Hematologic MalignancyAcute LeukemiaRemission+21 more
Masonic Cancer Center, University of Minnesota 70
Testing effectiveness (Phase 2)UnknownNCT02339350
What this trial is testing

Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in Children

Who this might be right for
Acute Lymphoblastic LeukemiaChild
The Korean Society of Pediatric Hematology Oncology 110
Testing effectiveness (Phase 2)Study completedNCT03128359
What this trial is testing

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Who this might be right for
Acute LeukemiaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center 38
Early research (Phase 1)Looking for participantsNCT06208735
What this trial is testing

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

Who this might be right for
B-Cell LeukemiaNon-Hodgkin's LymphomaB-cell Acute Lymphoblastic Leukemia+5 more
British Columbia Cancer Agency 24
Large-scale testing (Phase 3)UnknownNCT00003815
What this trial is testing

Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma
Scotland and Newcastle Lymphoma Group
Early research (Phase 1)Ended earlyNCT00589316
What this trial is testing

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+7 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT02765997
What this trial is testing

StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+1 more
Masonic Cancer Center, University of Minnesota
Early research (Phase 1)Study completedNCT05775406
What this trial is testing

Safety and Clinical Activity of KT-253 in Adult Patients with High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors

Who this might be right for
Myeloid MalignanciesAcute Lymphocytic LeukemiaLymphomas+1 more
Kymera Therapeutics, Inc. 52
Testing effectiveness (Phase 2)Looking for participantsNCT06698003
What this trial is testing

Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1

Who this might be right for
T-Cell Leukemia/Lymphoma, AdultT-cell Leukemia/LymphomaT-cell Leukemia+1 more
Memorial Sloan Kettering Cancer Center 134
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Early research (Phase 1)Active Not RecruitingNCT02935257
What this trial is testing

Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19

Who this might be right for
Leukemia, Lymphoblastic, Acute, Lymphoma
University College, London 72
Early research (Phase 1)Study completedNCT01169012
What this trial is testing

PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemias

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+1 more
UNC Lineberger Comprehensive Cancer Center 13
Testing effectiveness (Phase 2)Ended earlyNCT00185679
What this trial is testing

Haploid Allogeneic Transplant Using the CliniMACS System

Who this might be right for
Acute Myelogenous Leukemia (AML) - Relapsed, Primary Refractory Disease or Poor Risk FactorsChronic Myelogenous Leukemia (CML) - Accelerated or Second Chronic PhaseMyelodysplastic Syndrome (MDS) - High and Intermediate Risk+2 more
Ginna Laport 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06438796
What this trial is testing

Blinatumomab Maintenance After Allo-HSCT

Who this might be right for
High Risk Acute Lymphoblastic Leukemia
Ruijin Hospital 59
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