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Results for “Adenocarcinomas of the Gastroesophageal Junction”

488 trials

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Showing 20 of 488 results

Not applicableLooking for participantsNCT04850729
What this trial is testing

Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Nanfang Hospital, Southern Medical University 169
Testing effectiveness (Phase 2)Active Not RecruitingNCT06680622
What this trial is testing

Bemarituzumab in FGFR2b+ Patients With Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed at Least One Prior Line of Palliative Chemotherapy

Who this might be right for
Metastatic Gastro-esophageal Adenocarcinoma
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 126
Testing effectiveness (Phase 2)Looking for participantsNCT07483567
What this trial is testing

IBI343 in Combination With Sintilimab and SOX Regimen for Perioperative Treatment of Resectable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
CLDN18.2 PositivePrimary Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Innovent Biologics (Suzhou) Co. Ltd. 90
Testing effectiveness (Phase 2)UnknownNCT03368131
What this trial is testing

Concurrent Neoadjuvant Chemoradiotherapy Plus Trastuzumab in the Treatment of Siewert II ，III of Human Epidermal Growth Factor Receptor-2(HER-2) Positive Gastroesophageal Junction Adenocarcinoma： A Randomized, Controlled Clinical Study

Who this might be right for
Gastroesophageal Junction Adenocarcinoma
Hebei Medical University 48
Large-scale testing (Phase 3)Study completedNCT03081143
What this trial is testing

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy

Who this might be right for
Advanced Gastric or EGJ Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 429
Testing effectiveness (Phase 2)Looking for participantsNCT07488676
What this trial is testing

ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

Who this might be right for
Gastric or Gastro-esophageal Junction (GEJ) AdenocarcinomaPancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 150
Not applicableWithdrawnNCT05001360
What this trial is testing

Study of FMT Combined With Nivolumab in Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaEsophagogastric Junction AdenocarcinomaEsophagus Adenocarcinoma
Fujian Cancer Hospital
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Early research (Phase 1)Active Not RecruitingNCT05382364
What this trial is testing

Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)

Who this might be right for
Metastatic HER2+ Advanced Breast CancerBreast NeoplasmsGastric or Gastroesophageal Junction Adenocarcinoma (GEC)+1 more
Pfizer 25
Not applicableLooking for participantsNCT06300879
What this trial is testing

A Prospective Study on Esophagogastrostomy by an Innovative Surgical Technique

Who this might be right for
Gastric CancerAdenocarcinoma of Esophagogastric Junction
Huashan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07483554
What this trial is testing

IBI343 in Combination Therapy for Advanced Malignant Solid Tumors

Who this might be right for
CLDN18.2 PositiveGastric/Gastroesophageal Junction AdenocarcinomaPancreatic Ductal Adenocarcinoma
Innovent Biologics (Suzhou) Co. Ltd. 389
Testing effectiveness (Phase 2)Ended earlyNCT00493025
What this trial is testing

Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery

Who this might be right for
Esophageal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 19
Testing effectiveness (Phase 2)Looking for participantsNCT06750185
What this trial is testing

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 248
Large-scale testing (Phase 3)Looking for participantsNCT05677490
What this trial is testing

MFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastric AdenocarcinomaAdvanced Gastroesophageal Junction Adenocarcinoma+12 more
Alliance for Clinical Trials in Oncology 382
Testing effectiveness (Phase 2)Active Not RecruitingNCT06423885
What this trial is testing

BL-M07D1 Combination Therapy in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma
Sichuan Baili Pharmaceutical Co., Ltd. 64
Early research (Phase 1)Looking for participantsNCT04361708
What this trial is testing

Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies

Who this might be right for
Pancreatic AdenocarcinomaGastroesophageal Junction AdenocarcinomaAdenocarcinoma
University of Chicago 54
Not applicableStudy completedNCT01216813
What this trial is testing

Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological Cancer

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionCervical CancerEndometrial Cancer+7 more
Royal Marsden NHS Foundation Trust 33
Early research (Phase 1)Active Not RecruitingNCT04391049
What this trial is testing

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastroesophageal Junction AdenocarcinomaClinical Stage II Esophageal Adenocarcinoma AJCC v8+30 more
NRG Oncology 16
Not applicableStudy completedNCT04517747
What this trial is testing

Ramucirumab Plus TAS-102 in Patients With Advanced or Metastatic Gastric Adenocarcinoma or the Gastroesophageal Junction

Who this might be right for
Gastric AdenocarcinomaMetastatic Adenocarcinoma of the Gastroesophageal Junction
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 20
Not applicableNot Yet RecruitingNCT07625735
What this trial is testing

MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastric Cancer

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsLymph Node Metastasis+1 more
Shanghai Zhongshan Hospital 3,000
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