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Results for “Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT00018018
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency

Who this might be right for
Severe Combined Immunodeficiency Syndrome
National Human Genome Research Institute (NHGRI) 8
Not applicableEnrolling By InvitationNCT01186913
What this trial is testing

Natural History Study of SCID Disorders

Who this might be right for
Severe Combined Immunodeficiency (SCID)Leaky SCIDOmenn Syndrome+3 more
National Institute of Allergy and Infectious Diseases (NIAID) 690
Not applicableUnknownNCT05300373
What this trial is testing

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 100
Testing effectiveness (Phase 2)Study completedNCT01380990
What this trial is testing

Lentiviral (LV) Gene Therapy for Adenosine Deaminase (ADA) Deficiency

Who this might be right for
Adenosine Deaminase DeficiencySevere Combined Immunodeficiencies (SCID)
Great Ormond Street Hospital for Children NHS Foundation Trust 36
Post-approval studies (Phase 4)WithdrawnNCT03311074
What this trial is testing

Retroviral Insertion Site Methodology Study

Who this might be right for
Immune System Diseases
Fondazione Telethon
Not applicableStudy completedNCT03232203
What this trial is testing

Evaluating the Effectiveness of STRIMVELIS Risk Minimization Measures (RMMs)

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
Fondazione Telethon 16
Not applicableEnrolling By InvitationNCT04049084
What this trial is testing

An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID

Who this might be right for
Adenosine Deaminase DeficiencySevere Combined Immunodeficiency (SCID)
University of California, Los Angeles 70
Large-scale testing (Phase 3)Study completedNCT01420627
What this trial is testing

EZN-2279 in Patients With ADA-SCID

Who this might be right for
ADA-SCIDAdenosine Deaminase DeficiencySevere Combined Immunodeficiency
Leadiant Biosciences, Inc. 7
Testing effectiveness (Phase 2)Study completedNCT01279720
What this trial is testing

Gene Therapy ADA Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 8
Not applicableStudy completedNCT03878069
What this trial is testing

Registry Study of Revcovi Treatment in Patients With ADA-SCID

Who this might be right for
Adenosine Deaminase Severe Combined Immunodeficiency
Chiesi Farmaceutici S.p.A. 32
Not applicableStudy completedNCT00043225
What this trial is testing

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Who this might be right for
Psuedomas InfectionCystic Fibrosis
National Heart, Lung, and Blood Institute (NHLBI) 76
Not applicableStudy completedNCT00001255
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 10
Not applicableWithdrawnNCT01182857
What this trial is testing

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

Who this might be right for
ADA-SCID
National Human Genome Research Institute (NHGRI)
Testing effectiveness (Phase 2)Study completedNCT02999984
What this trial is testing

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
University of California, Los Angeles 10
Testing effectiveness (Phase 2)Study completedNCT03765632
What this trial is testing

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
Great Ormond Street Hospital for Children NHS Foundation Trust 13
Large-scale testing (Phase 3)WithdrawnNCT04140539
What this trial is testing

A Clinical Study to Enable Process Validation of Commercial Grade OTL-101

Who this might be right for
Severe Combined Immunodeficiency Due to ADA Deficiency
University of California, Los Angeles
Not applicableUnknownNCT05300334
What this trial is testing

Investigation of ADA Enzyme Deficiency

Who this might be right for
Adenosine Deaminase Deficiency
TRPHARM 800
Not applicableNot Yet RecruitingNCT03645460
What this trial is testing

Gene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)

Who this might be right for
Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)
Shenzhen Geno-Immune Medical Institute 10
Early research (Phase 1)Study completedNCT02022696
What this trial is testing

Treatment of SCID Due to ADA Deficiency With Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells After Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

Who this might be right for
Adenosine Deaminase DeficiencyADA-SCID
National Human Genome Research Institute (NHGRI) 1
Testing effectiveness (Phase 2)Study completedNCT00794508
What this trial is testing

MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency
Donald B. Kohn, M.D. 10
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