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Results for “Adjunctive Treatment of Major Depressive Disorder”

140 trials

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Showing 20 of 140 results

Testing effectiveness (Phase 2)Ended earlyNCT01554176
What this trial is testing

Safety and Efficacy of MK-6096 as Adjunctive Therapy in Participants With Major Depressive Disorder And Partial Response to Antidepressant Monotherapy (MK-6096-022)

Who this might be right for
Major Depressive Disorder, Recurrent
Merck Sharp & Dohme LLC 129
Large-scale testing (Phase 3)Study completedNCT00683852
What this trial is testing

A Double-Blind, Placebo-Controlled Study of Aripiprazole Adjunctive to Antidepressant Therapy

Who this might be right for
Major Depressive Disorder
Massachusetts General Hospital 225
Testing effectiveness (Phase 2)Study completedNCT01941043
What this trial is testing

A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Study of CERC-301 in the Adjunctive Treatment of Subjects With Severe Depression and Recent Active Suicidal Ideation Despite Antidepressant Treatment

Who this might be right for
Major Depressive Disorder
Avalo Therapeutics, Inc. 1,357
Large-scale testing (Phase 3)Not Yet RecruitingNCT07412756
What this trial is testing

Brenipatide in Adult Participants With Major Depressive Disorder

Who this might be right for
Depressive Disorder, Major
Eli Lilly and Company 1,000
Large-scale testing (Phase 3)Study completedNCT03538691
What this trial is testing

A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 1,149
Large-scale testing (Phase 3)Ended earlyNCT01944969
What this trial is testing

Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
H. Lundbeck A/S 26
Post-approval studies (Phase 4)Study completedNCT00231959
What this trial is testing

Effectiveness of Pramipexole for Treatment-Resistant Depression

Who this might be right for
Depression
Massachusetts General Hospital 65
Testing effectiveness (Phase 2)Study completedNCT00844922
What this trial is testing

Safety of Org 34517 900 mg in Patients Who Received Org 34517 in a Previous Trial (Study 28133/P05842)

Who this might be right for
Depressive DisordersPsychotic DisordersDepression
Merck Sharp & Dohme LLC 16
Large-scale testing (Phase 3)Study completedNCT04513912
What this trial is testing

Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Who this might be right for
Depressive Disorder, Major
Janssen Research & Development, LLC 757
Large-scale testing (Phase 3)Study completedNCT01403662
What this trial is testing

Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression

Who this might be right for
Bipolar DisorderBipolar DepressionBipolar I Depression+1 more
University Health Network, Toronto 29
Large-scale testing (Phase 3)Study completedNCT01360632
What this trial is testing

Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)

Who this might be right for
Depressive DisorderDepressionDepressive Disorder, Major+2 more
Otsuka Pharmaceutical Development & Commercialization, Inc. 1,539
Large-scale testing (Phase 3)Ended earlyNCT03487198
What this trial is testing

The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Beijing Research Institute 65
Large-scale testing (Phase 3)Ended earlyNCT01121536
What this trial is testing

Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Depression
Cephalon 867
Large-scale testing (Phase 3)Looking for participantsNCT06911112
What this trial is testing

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Who this might be right for
Major Depressive Disorder
Neurocrine Biosciences 200
Large-scale testing (Phase 3)Study completedNCT04985942
What this trial is testing

Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Intra-Cellular Therapies, Inc. 485
Large-scale testing (Phase 3)Study completedNCT01838876
What this trial is testing

Long-term Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Forest Laboratories 442
Large-scale testing (Phase 3)Study completedNCT05550532
What this trial is testing

Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Who this might be right for
Depressive Disorder, MajorAnhedonia
Janssen Research & Development, LLC 444
Testing effectiveness (Phase 2)Study completedNCT00854100
What this trial is testing

Safety and Efficacy of Cariprazine As Adjunctive Therapy In Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Forest Laboratories 231
Not applicableStudy completedNCT04770285
What this trial is testing

Trial to Evaluate the Effectiveness of a Digital Therapeutics in Adults Diagnosed With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 386
Large-scale testing (Phase 3)Study completedNCT01155661
What this trial is testing

A Safety Study in Participants With Major Depressive Disorder

Who this might be right for
Depressive Disorder, Major
Eli Lilly and Company 608
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