Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Adjunctive Treatment of Major Depressive Disorder”

Showing 20 of 0 results

Post-approval studies (Phase 4)Study completedNCT01670019
What this trial is testing

Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression

Who this might be right for
Major Depressive Disorder Without Psychotic Features
Duke University 46
Large-scale testing (Phase 3)Study completedNCT01838681
What this trial is testing

Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment

Who this might be right for
Major Depressive Disorder
H. Lundbeck A/S 1,986
Large-scale testing (Phase 3)Study completedNCT01305408
What this trial is testing

Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Depression
Cephalon 399
Large-scale testing (Phase 3)Ended earlyNCT04532749
What this trial is testing

Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Who this might be right for
Depressive Disorder, Major
Janssen Research & Development, LLC 212
Post-approval studies (Phase 4)Not Yet RecruitingNCT07369115
What this trial is testing

Neurocircuitry Mechanisms and Efficacy of Lumateperone as Adjunctive Therapy for Major Depressive Disorder and History of Early Life Abuse

Who this might be right for
Major Depressive DiorderEarly Life Trauma
University of Texas at Austin 50
Large-scale testing (Phase 3)Study completedNCT03737474
What this trial is testing

A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Co., Ltd. 248
Testing effectiveness (Phase 2)Study completedNCT00481195
What this trial is testing

Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Who this might be right for
Bipolar I Depression
Cephalon 257
Not applicableStudy completedNCT02579343
What this trial is testing

Adjunctive Treatment of Major Depression Utilizing Auricular Acupuncture

Who this might be right for
Major Depressive Disorder
Florida Gulf Coast University 13
Testing effectiveness (Phase 2)Study completedNCT03321526
What this trial is testing

Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Who this might be right for
Depressive Disorder, Major
Janssen Research & Development, LLC 107
Large-scale testing (Phase 3)Looking for participantsNCT06830044
What this trial is testing

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder (MDD)
Vanda Pharmaceuticals 500
Large-scale testing (Phase 3)Study completedNCT01187407
What this trial is testing

Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) Treatment

Who this might be right for
Major Depressive Disorder (MDD)
Eli Lilly and Company 1,480
Large-scale testing (Phase 3)Study completedNCT00095823
What this trial is testing

Adjunctive Aripiprazole in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Bristol-Myers Squibb 1,200
Testing effectiveness (Phase 2)Study completedNCT01457677
What this trial is testing

ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment

Who this might be right for
Major Depressive Disorder
Hoffmann-La Roche 357
Large-scale testing (Phase 3)Looking for participantsNCT07196501
What this trial is testing

Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Who this might be right for
Major Depressive Disorder
Neurocrine Biosciences 550
Large-scale testing (Phase 3)Study completedNCT02943564
What this trial is testing

Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)

Who this might be right for
Depressive Disorder, Major
Naurex, Inc, an affiliate of Allergan plc 658
Early research (Phase 1)Study completedNCT04937829
What this trial is testing

Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication

Who this might be right for
Depressive Disorder, Major
Boehringer Ingelheim 59
Testing effectiveness (Phase 2)Study completedNCT05593029
What this trial is testing

A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Development & Commercialization, Inc. 929
Testing effectiveness (Phase 2)Study completedNCT01582815
What this trial is testing

JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms

Who this might be right for
Major Depressive Disorder
Janssen Research & Development, LLC 121
Large-scale testing (Phase 3)Study completedNCT00876343
What this trial is testing

Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Otsuka Pharmaceutical Co., Ltd. 586
Large-scale testing (Phase 3)Ended earlyNCT00868374
What this trial is testing

Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder

Who this might be right for
Major Depressive DisorderGeneralized Anxiety Disorder
Keming Gao 23
Next Page

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation