Not applicableStudy completedNCT02113917What this trial is testingChildren and Adult Hemophagocytic Syndrome (HLHa)Who this might be right forHemophagocytic Syndrome Assistance Publique - Hôpitaux de Paris 204
Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040What this trial is testingLenalidomide for Adult Histiocyte DisordersWho this might be right forLangerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS) Dana-Farber Cancer Institute 12
Not applicableActive Not RecruitingNCT05236764What this trial is testingHaploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 DepletionWho this might be right forAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more Baylor College of Medicine 3
Large-scale testing (Phase 3)UnknownNCT03742115What this trial is testingEtoposide in the First-line Treatment of Adult EBV-HLHWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 90
Large-scale testing (Phase 3)Not Yet RecruitingNCT07440290What this trial is testingDETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.Who this might be right forHaematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+16 more Cancer Research UK 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367What this trial is testingCD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell TransplantationWho this might be right forBone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more Diane George 37
Testing effectiveness (Phase 2)Looking for participantsNCT07187193What this trial is testingEfficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCHWho this might be right forLangerhans Cell Histiocytosis Cancer Institute and Hospital, Chinese Academy of Medical Sciences 50
Testing effectiveness (Phase 2)Study completedNCT06949358What this trial is testingEvaluate Safety and Tolerability of Olipudase Alfa in Pediatric and Adult Participants With Acid Sphingomyelinase Deficiency (ASMD) Who Completed the DFI12712 or the LTS13632 Study in FranceWho this might be right forAcid Sphingomyelinase Deficiency Sanofi 3
Not applicableLooking for participantsNCT04665674What this trial is testingAdult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort StudyWho this might be right forHistiocytosisHistiocytosis, Langerhans-CellHistiocytosis Pulmonary Assistance Publique - Hôpitaux de Paris 500
Testing effectiveness (Phase 2)Study completedNCT01273766What this trial is testingDeferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic MalignanciesWho this might be right forAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+133 more Wake Forest University Health Sciences 16
Large-scale testing (Phase 3)Ended earlyNCT03985423What this trial is testingEvaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLHWho this might be right forHemophagocytic Lymphohistiocytoses Swedish Orphan Biovitrum 7
Testing effectiveness (Phase 2)Looking for participantsNCT01962415What this trial is testingReduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCTWho this might be right forPrimary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more Paul Szabolcs 100
Not applicableLooking for participantsNCT03117010What this trial is testingProspective Cohort for Adult HemophagocytosisWho this might be right forHemophagocytic Lymphohistiocytoses Samsung Medical Center 81
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800What this trial is testingCD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell TransplantWho this might be right forChronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more Diane George 14
Testing effectiveness (Phase 2)Study completedNCT02385110What this trial is testingAlemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic LymphohistiocytosisWho this might be right forLeukemia M.D. Anderson Cancer Center 18
Testing effectiveness (Phase 2)Study completedNCT03311854What this trial is testingInvestigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)Who this might be right forMacrophage Activation SyndromeLymphohistiocytosis, HemophagocyticArthritis, Juvenile+1 more Swedish Orphan Biovitrum 14
Not applicableStudy completedNCT06047210What this trial is testingEvaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytoses Swedish Orphan Biovitrum 14
Not applicableLooking for participantsNCT06197204What this trial is testingBiomarkers for Diagnostic, Prognostic and of Response to Treatment in Adult Langerhans Cell HistiocytosisWho this might be right forHistiocytosis, Langerhans-Cell Assistance Publique - Hôpitaux de Paris 570
Not applicableStudy completedNCT05359276What this trial is testingData Analysis of Adult and Pediatric Participants With Acid Sphingomyelinase Deficiency (ASMD) on Early Access to Olipudase Alfa in FranceWho this might be right forAcid Sphingomyelinase Deficiency (ASMD) Sanofi 40
Not applicableLooking for participantsNCT05936086What this trial is testingControlled Study of High-dose Cyclophosphamide Induction Therapy in Adult Patients With HLHWho this might be right forHemophagocytic Syndrome shifeng Lou 160