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Results for “Adult Malignant Peripheral Nerve Sheath Tumor”

74 trials

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Showing 20 of 74 results

Testing effectiveness (Phase 2)Ended earlyNCT04530487
What this trial is testing

Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults

Who this might be right for
Desmoplastic Small Round Cell TumorEwing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Desmoplastic Small Round Cell Tumor+9 more
M.D. Anderson Cancer Center 1
Large-scale testing (Phase 3)Active Not RecruitingNCT02180867
What this trial is testing

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Who this might be right for
Alveolar Soft Part SarcomaAngiomatoid Fibrous HistiocytomaAtypical Fibroxanthoma+33 more
National Cancer Institute (NCI) 140
Early research (Phase 1)Study completedNCT00450736
What this trial is testing

Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery

Who this might be right for
Childhood Malignant Fibrous Histiocytoma of BoneSarcoma
University of Miami 3
Testing effectiveness (Phase 2)Looking for participantsNCT06849986
What this trial is testing

IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)

Who this might be right for
Soft Tissue SarcomasAngiosarcomaFibrosarcoma+4 more
Fudan University 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 798
Testing effectiveness (Phase 2)Study completedNCT03719430
What this trial is testing

APX005M and Doxorubicin in Advanced Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Alexander Z. Wei, MD 27
Large-scale testing (Phase 3)Ended earlyNCT01132547
What this trial is testing

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Who this might be right for
Cancer
University of South Florida 22
Early research (Phase 1)Study completedNCT01119599
What this trial is testing

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

Who this might be right for
Acoustic SchwannomaAdult Anaplastic (Malignant) MeningiomaAdult Anaplastic Astrocytoma+26 more
National Cancer Institute (NCI) 22
Not applicableActive Not RecruitingNCT00924196
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type I

Who this might be right for
Neurofibromatosis Type 1Malignant Peripheral Nerve Sheath TumorPlexiform Neurofibroma+2 more
National Cancer Institute (NCI) 259
Testing effectiveness (Phase 2)Study completedNCT01653028
What this trial is testing

Alisertib in Treating Patients With Advanced or Metastatic Sarcoma

Who this might be right for
MyxofibrosarcomaRecurrent Adult Soft Tissue SarcomaRecurrent Leiomyosarcoma+5 more
National Cancer Institute (NCI) 72
Early research (Phase 1)Study completedNCT04811196
What this trial is testing

Different Dosing Schedules of Selinexor in Sarcoma Patients

Who this might be right for
Soft Tissue SarcomaMalignant Peripheral Nerve Sheath Tumor (MPNST)Leiomyosarcoma+1 more
University Health Network, Toronto 56
Testing effectiveness (Phase 2)Study completedNCT01154452
What this trial is testing

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

Who this might be right for
Adult Alveolar Soft Part SarcomaAdult AngiosarcomaAdult Desmoplastic Small Round Cell Tumor+32 more
National Cancer Institute (NCI) 78
Testing effectiveness (Phase 2)Study completedNCT00304083
What this trial is testing

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

Who this might be right for
Neurofibromatosis Type 1Sarcoma
Sarcoma Alliance for Research through Collaboration 48
Not applicableNo Longer AvailableNCT03874455
What this trial is testing

Tazemetostat Expanded Access Program for Adults With Solid Tumors

Who this might be right for
Epithelioid Sarcoma (Ex-US Only)Spindle Cell SarcomaSinonasal Carcinoma+17 more
Epizyme, Inc.
Not applicableStudy completedNCT04774289
What this trial is testing

Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)

Who this might be right for
Neurofibromatosis 1Peripheral Nerve Neoplasms, Malignant
National Cancer Institute (NCI) 296
Early research (Phase 1)Study completedNCT03009201
What this trial is testing

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Who this might be right for
Advanced Soft Tissue SarcomaLocally Advanced AngiosarcomaLocally Advanced Leiomyosarcoma+24 more
OHSU Knight Cancer Institute 16
Testing effectiveness (Phase 2)Looking for participantsNCT04872543
What this trial is testing

ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)

Who this might be right for
Malignant Peripheral Nerve Sheath Tumors (MPNST)
Memorial Sloan Kettering Cancer Center 25
Very early researchLooking for participantsNCT06693284
What this trial is testing

A Window of Opportunity Trial of Mirdametinib Plus Vorinostat for NF1 Associated, H3K27 Trimethylation Deficient Malignant Peripheral Nerve Sheath Tumor [MPNST]

Who this might be right for
Primary Malignant Peripheral Nerve Sheath Tumors
University of Minnesota 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06735820
What this trial is testing

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

Who this might be right for
Malignant Peripheral Nerve Sheath Tumor (MPNST)Neurofibromatosis 1 (NF1)Atypical Neurofibroma
AeRang Kim 45
Testing effectiveness (Phase 2)Ended earlyNCT00740597
What this trial is testing

Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma

Who this might be right for
Sarcoma
City of Hope Medical Center 1
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