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Results for “Adult Myelodysplastic Syndrome”

1,859 trials

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Showing 20 of 1,859 results

Early research (Phase 1)Ended earlyNCT02641002
What this trial is testing

CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 28
Not applicableStudy completedNCT00521430
What this trial is testing

Donor Stem Cell Transplant After Conditioning Therapy in Treating Patients With Hematologic Cancer, Recurrent or Metastatic Solid Tumor, or Other Disease

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+3 more
Asan Medical Center 30
Testing effectiveness (Phase 2)UnknownNCT01423175
What this trial is testing

ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS

Who this might be right for
Acute Myeloid LeukemiaMDS
Hannover Medical School 60
Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Early research (Phase 1)Looking for participantsNCT05292664
What this trial is testing

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Who this might be right for
Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more
Andrew E. Place, MD 30
Early research (Phase 1)Study completedNCT00161187
What this trial is testing

Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor

Who this might be right for
Cancer
University of Medicine and Dentistry of New Jersey 37
Early research (Phase 1)Not Yet RecruitingNCT07254793
What this trial is testing

Prophylactic and Therapeutic DLI-X for Leukemia Relapse After HCT

Who this might be right for
Acute Lymphoid LeukemiaAcute Myeloid LeukemiaAcute Undifferentiated Leukemia (AUL)+3 more
University of Arizona 94
Testing effectiveness (Phase 2)WithdrawnNCT01652014
What this trial is testing

Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+51 more
University of Medicine and Dentistry of New Jersey
Testing effectiveness (Phase 2)Ended earlyNCT06563804
What this trial is testing

Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML

Who this might be right for
Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)/AMLChronic Myelomonocytic Leukemia (CMML)
Servier Bio-Innovation LLC 13
Not applicableUnknownNCT01252784
What this trial is testing

Reduced-intensity Conditioning Allogeneic Hematopoietic Cell Transplantation

Who this might be right for
Myelodysplastic Syndrome
Cooperative Study Group A for Hematology 20
Large-scale testing (Phase 3)Study completedNCT05630001
What this trial is testing

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan.

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 52
Early research (Phase 1)Study completedNCT00278330
What this trial is testing

Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Adult Acute Myeloid Leukemia+4 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)WithdrawnNCT03602898
What this trial is testing

Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic Leukemia+10 more
Fred Hutchinson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Early research (Phase 1)Active Not RecruitingNCT04281199
What this trial is testing

TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCT

Who this might be right for
Acute LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center 20
Early research (Phase 1)Ended earlyNCT00852709
What this trial is testing

Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemias

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaMyeloproliferative Disorders+7 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Testing effectiveness (Phase 2)Study completedNCT00217594
What this trial is testing

A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
National Heart, Lung, and Blood Institute (NHLBI) 40
Testing effectiveness (Phase 2)Study completedNCT01893372
What this trial is testing

Eltrombopag With or Without Hypomethylating Agent After Hypomethylating Agent Failure For Patients With Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 29
Early research (Phase 1)Study completedNCT00741234
What this trial is testing

A Phase I Dose Escalation Study of Oral SB939 Administered Alone or With Azacitidine

Who this might be right for
Solid TumorsHematologic MalignanciesMyelodysplastic Syndrome
S*BIO 85
Testing effectiveness (Phase 2)Study completedNCT00416598
What this trial is testing

Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia With Myelodysplasia-Related ChangesAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11+4 more
National Cancer Institute (NCI) 546
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