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Results for “Advanced/Metastatic”

7,631 trials

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Showing 20 of 7,631 results

Testing effectiveness (Phase 2)Study completedNCT04632992
What this trial is testing

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

Who this might be right for
Advanced Unresectable or Metastatic Solid Malignancy
Genentech, Inc. 252
Large-scale testing (Phase 3)Active Not RecruitingNCT04603807
What this trial is testing

Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 217
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Testing effectiveness (Phase 2)Looking for participantsNCT03624244
What this trial is testing

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)

Who this might be right for
Low Grade Endometrial Stromal Sarcoma
Centre Leon Berard 40
Testing effectiveness (Phase 2)Study completedNCT00101400
What this trial is testing

BAY43-9006 - Phase II in Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsBreast Cancer
Bayer 54
Testing effectiveness (Phase 2)Study completedNCT02768207
What this trial is testing

Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma

Who this might be right for
Metastatic Melanoma
Hoffmann-La Roche 40
Testing effectiveness (Phase 2)Study completedNCT03046992
What this trial is testing

Clinical Trial of YH25448 in Patients with EGFR Mutation Positive Advanced NSCLC

Who this might be right for
EGFR Gene Mutation
Yuhan Corporation 224
Early research (Phase 1)Study completedNCT03132792
What this trial is testing

AFPᶜ³³²T in Advanced HCC

Who this might be right for
Hepatocellular CancerAFP Expressing Tumors
Adaptimmune 39
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Not applicableStudy completedNCT06919107
What this trial is testing

Advanced Footwear Technology in Federated Athletes

Who this might be right for
Athlete Foot
University of Oviedo 134
Testing effectiveness (Phase 2)Study completedNCT00964171
What this trial is testing

Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Institut Bergonié 19
Early research (Phase 1)Ended earlyNCT05904236
What this trial is testing

Safety and Tolerability of Intravenous Administration of ICVB-1042

Who this might be right for
Patients With Advanced Solid Tumors
IconOVir Bio 17
Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Testing effectiveness (Phase 2)Ended earlyNCT00321308
What this trial is testing

Trial of Pemetrexed With or Without PF-3512676 in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small Cell Lung
Pfizer 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06094868
What this trial is testing

Clinical Study of Fruquintinib Combined With Sintilimab and XELOX Regimen in the Treatment of Advanced Cancer

Who this might be right for
Gastric Cancer
Second Affiliated Hospital of Nanchang University 45
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Testing effectiveness (Phase 2)Study completedNCT00002608
What this trial is testing

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Who this might be right for
Adrenocortical CarcinomaBrain and Central Nervous System TumorsHead and Neck Cancer+4 more
Ottawa Regional Cancer Centre 30
Early research (Phase 1)Study completedNCT01798108
What this trial is testing

Dose Escalation Study of Radium-223 Dichloride in Patients With Advanced Skeletal Metastases

Who this might be right for
Neoplasm Metastasis
Bayer 31
Early research (Phase 1)Study completedNCT02719691
What this trial is testing

Phase I Study of MLN0128 and MLN8237 in Patients With Advanced Solid Tumors and Metastatic Triple-negative Breast Cancer

Who this might be right for
Metastatic Breast CancerSolid Tumors
University of Colorado, Denver 47
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