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Results for “Advanced/Metastatic Head and Neck, Oesophageal and Cervical Cancers”

266 trials

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Showing 20 of 266 results

Testing effectiveness (Phase 2)Looking for participantsNCT06172478
What this trial is testing

HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMelanomaHead and Neck Cancer+11 more
Daiichi Sankyo 740
Testing effectiveness (Phase 2)Ended earlyNCT01832857
What this trial is testing

Phase 2 Safety, Tolerability and Efficacy Study of CPI-613 in Cancer Patients

Who this might be right for
Cancer
Cornerstone Pharmaceuticals 7
Testing effectiveness (Phase 2)Ended earlyNCT03829501
What this trial is testing

A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies

Who this might be right for
Squamous Cell Carcinoma of Head and NeckNon-small Cell Lung CancerHepatocellular Carcinoma+9 more
Kymab Limited 222
Large-scale testing (Phase 3)Study completedNCT04540211
What this trial is testing

Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma

Who this might be right for
Esophageal Cancer
Hoffmann-La Roche 461
Testing effectiveness (Phase 2)Study completedNCT02552121
What this trial is testing

Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

Who this might be right for
Ovary CancerCervix CancerEndometrium Cancer+4 more
Seagen Inc. 33
Early research (Phase 1)Study completedNCT03821233
What this trial is testing

A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers

Who this might be right for
HER2-expressing Cancers
Zymeworks BC Inc. 112
Testing effectiveness (Phase 2)Study completedNCT00002984
What this trial is testing

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus

Who this might be right for
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center 26
Large-scale testing (Phase 3)Study completedNCT02564263
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)

Who this might be right for
Esophageal CarcinomaEsophagogastric Junction Carcinoma
Merck Sharp & Dohme LLC 628
Testing effectiveness (Phase 2)Ended earlyNCT03386721
What this trial is testing

Basket Study to Evaluate the Therapeutic Activity of Simlukafusp Alfa as a Combination Therapy in Participants With Advanced and/or Metastatic Solid Tumors

Who this might be right for
Advanced/Metastatic Head and Neck, Oesophageal and Cervical Cancers
Hoffmann-La Roche 256
Early research (Phase 1)Looking for participantsNCT06545331
What this trial is testing

Study of XB010 in Subjects With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsEsophageal Squamous Cell CancerHead and Neck Squamous Cell Cancer+3 more
Exelixis 396
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Early research (Phase 1)Looking for participantsNCT06910657
What this trial is testing

IDOV-Immune for Advanced Solid Tumors

Who this might be right for
Colorectal CancerPancreatic CancerMelanoma+13 more
ViroMissile, Inc. 78
Early research (Phase 1)Study completedNCT04672434
What this trial is testing

Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 48
Early research (Phase 1)Ended earlyNCT01705340
What this trial is testing

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionHER2-positive Breast CancerMale Breast Cancer+9 more
National Cancer Institute (NCI) 60
Not applicableNot Yet RecruitingNCT04616040
What this trial is testing

A Real-world Study Evaluating the Usage of Camrelizumab in Chinese Patients With Advanced Esophageal Cancer

Who this might be right for
Esophageal Cancer
Peking University 1,030
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Early research (Phase 1)Active Not RecruitingNCT03983954
What this trial is testing

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

Who this might be right for
ER+ Breast CancerOvarian CancerCervical Squamous Cell Carcinoma+17 more
NeoTX Therapeutics Ltd. 120
Early research (Phase 1)Active Not RecruitingNCT03170960
What this trial is testing

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Urothelial CarcinomaRenal Cell CarcinomaNon-Small Cell Lung Cancer+11 more
Exelixis 914
Testing effectiveness (Phase 2)Looking for participantsNCT05914116
What this trial is testing

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumors
DualityBio Inc. 862
Early research (Phase 1)Study completedNCT03518554
What this trial is testing

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Who this might be right for
Non-small Cell Lung CancerHead and Neck CancerEsophageal Cancer+1 more
Jacobio Pharmaceuticals Co., Ltd. 38
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