Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced/Metastatic Hepatocellular Carcinoma”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT04696055
What this trial is testing

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Who this might be right for
Hepatocellular Carcinoma
Bayer 95
Testing effectiveness (Phase 2)Looking for participantsNCT06811116
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI) 92
Large-scale testing (Phase 3)Study completedNCT03434379
What this trial is testing

Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Hoffmann-La Roche 558
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07495579
What this trial is testing

Lenvatinib or Regorafenib for Advanced Hepatocellular Carcinoma After Immunotherapy (REVIVE)

Who this might be right for
Hepatocellular Carcinoma (HCC)
Asan Medical Center 146
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Large-scale testing (Phase 3)Not Yet RecruitingNCT06680258
What this trial is testing

TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

Who this might be right for
Hepatocellular Carcinoma (HCC)
Tempest Therapeutics 740
Testing effectiveness (Phase 2)Ended earlyNCT04785287
What this trial is testing

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

Who this might be right for
Advanced Lung CarcinomaAdvanced Malignant Solid NeoplasmMalignant Adrenal Gland Neoplasm+14 more
M.D. Anderson Cancer Center 13
Early research (Phase 1)Looking for participantsNCT06687941
What this trial is testing

Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

Who this might be right for
NeoplasmsCarcinoma, HepatocellularCarcinoma, Non-Small-Cell Lung+1 more
Aptamer Sciences, Inc. 70
Testing effectiveness (Phase 2)WithdrawnNCT01859182
What this trial is testing

Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery

Who this might be right for
Adenocarcinoma of the GallbladderAdenocarcinoma With Squamous Metaplasia of the GallbladderAdult Primary Cholangiocellular Carcinoma+12 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT07623369
What this trial is testing

A First-in-Human Study of HH160 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Solid TumorNon-small Cell Lung CancerHepatocellular Carcinoma+9 more
Huahui Health 299
Testing effectiveness (Phase 2)Study completedNCT03941873
What this trial is testing

Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer

Who this might be right for
Carcinoma, HepatocellularGastric/Gastroesophageal Junction Cancer
BeiGene 111
Testing effectiveness (Phase 2)Looking for participantsNCT07312292
What this trial is testing

Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)

Who this might be right for
Liver Cancer (Locally Advanced or Metastatic)Liver Cancer Adult
Niek Wijnen 15
Early research (Phase 1)Ended earlyNCT00873002
What this trial is testing

Panobinostat and Sorafenib in Treating Patients With Liver Cancer That is Metastatic and/or Cannot Be Removed by Surgery

Who this might be right for
Liver Cancer
Case Comprehensive Cancer Center 3
Not applicableStudy completedNCT00739167
What this trial is testing

Quality of Life in Patients Undergoing Embolization Using Yttrium Y 90 Glass Microspheres for Primary or Metastatic Liver Cancer

Who this might be right for
Liver CancerMetastatic Cancer
Northwestern University 74
Large-scale testing (Phase 3)Study completedNCT01015833
What this trial is testing

Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Advanced Adult Hepatocellular CarcinomaRecurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v7+7 more
National Cancer Institute (NCI) 356
Very early researchUnknownNCT03965546
What this trial is testing

ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer

Who this might be right for
Hepatocellular CarcinomaLiver CancerLiver Neoplasms+1 more
First Affiliated Hospital Xi'an Jiaotong University 27
Early research (Phase 1)Not Yet RecruitingNCT07583316
What this trial is testing

First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

Who this might be right for
Lung Cancer (Locally Advanced or Metastatic)Esophagus CancerHead and Neck Cancer+1 more
Corregene Biotechnology Co., Ltd 192
Not applicableUnknownNCT01230697
What this trial is testing

Perspective Evaluation of Hormones Involved in Serum Phosphate Homeostasis in Patients With Metastatic Renal Cells Carcinoma or Hepatocellular Carcinoma Treated With Sorafenib (SORHORM)

Who this might be right for
Kidney CancerLiver Cancer
University of Turin, Italy 60
Early research (Phase 1)Study completedNCT04338685
What this trial is testing

A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases

Who this might be right for
Carcinoma, HepatocellularBiliary Tract CancerSecondary Liver Cancer+1 more
Hoffmann-La Roche 55
Next Page