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Results for “Advanced/Metastatic Medullary Thyroid Cancer (MTC)”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Study completedNCT00654238
What this trial is testing

Phase II Trial of Sorafenib (Nexavar) in Patients With Advanced Thyroid Cancer

Who this might be right for
Metastatic Differentiated Thyroid CancerMetastatic Poorly Differentiated Thyroid CancerMetastatic Anaplastic Thyroid Cancer+1 more
University of Pennsylvania 59
Testing effectiveness (Phase 2)Ended earlyNCT00923247
What this trial is testing

A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC)

Who this might be right for
Medullary Thyroid Carcinoma
National Cancer Institute (NCI) 22
Testing effectiveness (Phase 2)Study completedNCT00390325
What this trial is testing

Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer

Who this might be right for
Hereditary Thyroid Gland Medullary CarcinomaLocally Advanced Thyroid Gland Medullary CarcinomaMultiple Endocrine Neoplasia Type 2A+8 more
National Cancer Institute (NCI) 21
Testing effectiveness (Phase 2)Study completedNCT00358956
What this trial is testing

Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Cancer

Who this might be right for
Thyroid Cancer
Genzyme, a Sanofi Company 19
Testing effectiveness (Phase 2)Study completedNCT00098345
What this trial is testing

Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer

Who this might be right for
Thyroid Cancer
Genzyme, a Sanofi Company 40
Testing effectiveness (Phase 2)Study completedNCT00121628
What this trial is testing

A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer

Who this might be right for
Thyroid Cancer
Amgen 184
Not applicableStudy completedNCT05507775
What this trial is testing

Digoxin for the Reinduction of Radioiodine Uptake in Metastatic or Locally Advanced Non-medullary Thyroid Carcinoma

Who this might be right for
Non-Medullary Thyroid Carcinoma
Radboud University Medical Center 8
Testing effectiveness (Phase 2)Study completedNCT00096083
What this trial is testing

Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Cancer
Delcath Systems Inc. 56
Early research (Phase 1)Active Not RecruitingNCT04514484
What this trial is testing

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

Who this might be right for
Advanced Differentiated Thyroid Gland CarcinomaAdvanced Head and Neck CarcinomaAdvanced Hepatocellular Carcinoma+60 more
National Cancer Institute (NCI) 8
Not applicableActive Not RecruitingNCT04970134
What this trial is testing

Spanish Study for Molecular Characterization of Thyroid Carcinoma

Who this might be right for
Differentiated Thyroid CarcinomaMedullary Thyroid Carcinoma
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello 150
Not applicableNot Yet RecruitingNCT07048964
What this trial is testing

A Prospective Cohort Study of Pralsetinib or Anlotinib in the Treatment of Locally Advanced and/or Metastatic Medullary Thyroid Carcinoma With RET Gene Mutations

Who this might be right for
Medullary Thyroid Cancer (MTC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02721732
What this trial is testing

Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic

Who this might be right for
Advanced Malignant Solid NeoplasmCarcinoma of Unknown PrimaryMetastatic Adrenal Gland Pheochromocytoma+16 more
M.D. Anderson Cancer Center 157
Early research (Phase 1)Study completedNCT00028496
What this trial is testing

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Adenocarcinoma of the ColonAdenocarcinoma of the GallbladderAdenocarcinoma of the Pancreas+39 more
National Cancer Institute (NCI) 48
Early research (Phase 1)WithdrawnNCT02831179
What this trial is testing

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Who this might be right for
Functional Pancreatic Neuroendocrine TumorMalignant SomatostatinomaMerkel Cell Carcinoma+26 more
Vanderbilt-Ingram Cancer Center
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)WithdrawnNCT04106843
What this trial is testing

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Who this might be right for
Locally Advanced Adrenal Gland PheochromocytomaLocally Advanced ParagangliomaMetastatic Adrenal Gland Pheochromocytoma+11 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT03838692
What this trial is testing

Ponatinib in Advanced or Metastatic Medullary Thyroid Cancer

Who this might be right for
Medullary Thyroid Cancer
Antonio Fojo
Large-scale testing (Phase 3)Study completedNCT00410761
What this trial is testing

An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer

Who this might be right for
Thyroid Cancer
Genzyme, a Sanofi Company 331
Not applicableStudy completedNCT01945762
What this trial is testing

Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer

Who this might be right for
Symptomatic, Aggressive, Sporadic, Unresectable, LocallyAdvanced/Metastatic Medullary Thyroid Cancer (MTC)
Genzyme, a Sanofi Company 31
Testing effectiveness (Phase 2)Study completedNCT00095836
What this trial is testing

Gefitinib in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer That Did Not Respond to Iodine Therapy

Who this might be right for
Head and Neck Cancer
Massachusetts General Hospital 27
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