Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Breast Cancer Brain Metastasis”

56 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 56 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Study completedNCT00049296
What this trial is testing

Thalidomide and Docetaxel in Treating Patients With Advanced Cancer

Who this might be right for
Cancer
Case Comprehensive Cancer Center 26
Not applicableUnknownNCT03896958
What this trial is testing

The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)

Who this might be right for
Cancer, All TypesCancer of LiverCancer of Stomach+42 more
SpeciCare 1,000
Early research (Phase 1)Study completedNCT01921335
What this trial is testing

ARRY-380 + Trastuzuamab for Breast w/ Brain Mets

Who this might be right for
Brain Metastases From HER2 and Breast CancerAdvanced HER2-positive Breast Cancer
Dana-Farber Cancer Institute 41
Early research (Phase 1)Study completedNCT00030498
What this trial is testing

Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction

Who this might be right for
Adult Anaplastic AstrocytomaAdult Anaplastic EpendymomaAdult Anaplastic Oligodendroglioma+83 more
National Cancer Institute (NCI) 75
Not applicableLooking for participantsNCT06839547
What this trial is testing

A Prospective, Multicenter, Observational Cohort Study to Evaluate the Efficacy and Safety of a Novel Anti-tumor Drug as a Radiosensitizer in Patients With Advanced Breast Cancer Brain Metastasis.

Who this might be right for
Advanced Breast Cancer Brain Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 100
Not applicableStudy completedNCT01077648
What this trial is testing

Brain Metastasis in Breast Cancer Patients

Who this might be right for
Cancer
GlaxoSmithKline 1
Early research (Phase 1)Study completedNCT04487236
What this trial is testing

Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsHER2-positive Breast Cancer
Suzhou Zanrong Pharma Limited 61
Early research (Phase 1)Looking for participantsNCT07540572
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Who this might be right for
ER+, HER 2- Breast CancerNon-small Cell Lung Cancer (NSCLC)Castration-resistant Prostate Cancer (CRPC)+1 more
IDEAYA Biosciences 160
Testing effectiveness (Phase 2)Looking for participantsNCT06718933
What this trial is testing

Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis

Who this might be right for
Breast Cancer MetastaticBreast Cancer Brain Metastases
Fudan University 74
Early research (Phase 1)WithdrawnNCT02915172
What this trial is testing

Lenvatinib and Capecitabine in Patients With Advanced Malignancies

Who this might be right for
Advanced CancerMalignant Neoplasm of BreastMalignant Neoplasms of Bone and Articular Cartilage+11 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT04420598
What this trial is testing

DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease

Who this might be right for
Advanced Breast CancerHER2-positive Breast CancerBrain Metastases+1 more
MedSIR 41
Not applicableStudy completedNCT00477919
What this trial is testing

E-MOSAIC Electronic Tool to Monitor Symptoms

Who this might be right for
Cancer
Swiss Cancer Institute 264
Testing effectiveness (Phase 2)WithdrawnNCT04856475
What this trial is testing

Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast Cancer

Who this might be right for
Breast CancerBrain Metastases
Jules Bordet Institute
Not applicableStudy completedNCT06504719
What this trial is testing

Safety and Efficacy Real-world Data of Trastuzumab Deruxtecan and Sacituzumab Govitecan

Who this might be right for
Breast CancerMetastatic Cancer
Hellenic Cooperative Oncology Group 312
Testing effectiveness (Phase 2)Looking for participantsNCT07100600
What this trial is testing

Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases

Who this might be right for
HER2-positive Advanced Breast CancerBrain MetastasesRadiotherapy
Henan Cancer Hospital 224
Early research (Phase 1)Looking for participantsNCT06458712
What this trial is testing

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Who this might be right for
Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency)
Duke Street Bio Ltd 180
Testing effectiveness (Phase 2)UnknownNCT06598046
What this trial is testing

A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC

Who this might be right for
Metastatic Breast Cancer
Henan Cancer Hospital 48
Testing effectiveness (Phase 2)Looking for participantsNCT06839560
What this trial is testing

Evaluating the Efficacy and Safety of PD-L1 Monoclonal Antibody Combined With VEX Metronomic Chemotherapy and Concurrent or Delayed Radiotherapy in Patients With Advanced HER2-Negative Breast Cancer With Brain Metastasis

Who this might be right for
Brain Metastasis From Advanced HER2-negative Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Next Page