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Results for “Advanced Cutaneous Squamous Cell Carcinoma”

129 trials

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Showing 20 of 129 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06295809
What this trial is testing

(Neo)Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)

Who this might be right for
Carcinoma, Squamous CellSkin Neoplasms
Merck Sharp & Dohme LLC 46
Testing effectiveness (Phase 2)Active Not RecruitingNCT05888844
What this trial is testing

Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Incyte Corporation 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944941
What this trial is testing

Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer

Who this might be right for
Skin Squamous Cell CarcinomaMetastatic Skin Cancer
Alliance for Clinical Trials in Oncology 60
Early research (Phase 1)Looking for participantsNCT07217171
What this trial is testing

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

Who this might be right for
Bladder CancerSquamous Cell Carcinoma of the LungEsophageal Squamous Cell Carcinoma+8 more
EvolveImmune United, Inc 160
Early research (Phase 1)Active Not RecruitingNCT05544929
What this trial is testing

Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Who this might be right for
Carcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more
Novartis Pharmaceuticals 126
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Early research (Phase 1)Study completedNCT01872923
What this trial is testing

Dose Escalating Study for Amphinex-based PCI of Bleomycin.

Who this might be right for
Cutaneous or Sub-cutaneous Malignancies
PCI Biotech AS 3
Not applicableWithdrawnNCT02507076
What this trial is testing

Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma

Who this might be right for
Basal Cell Carcinoma of the SkinEccrine Carcinoma of the SkinRecurrent Adult Soft Tissue Sarcoma+8 more
Albert Einstein College of Medicine
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
Not applicableNo Longer AvailableNCT03492489
What this trial is testing

Expanded Access Protocol for Cemiplimab in Metastatic or Locally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Cutaneous Squamous Cell Carcinoma
Regeneron Pharmaceuticals
Early research (Phase 1)Looking for participantsNCT04429542
What this trial is testing

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaSquamous Cell Carcinoma of Anal CanalColorectal Cancer+8 more
Bicara Therapeutics 292
Large-scale testing (Phase 3)Temporarily pausedNCT05050162
What this trial is testing

Comparing Cisplatin Every Three Weeks to Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell Carcinoma+7 more
NRG Oncology 1,714
Early research (Phase 1)Active Not RecruitingNCT02988960
What this trial is testing

ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 163
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Testing effectiveness (Phase 2)Looking for participantsNCT07094685
What this trial is testing

Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaStage II Head and Neck Cutaneous Squamous Cell Carcinoma+2 more
University of Michigan Rogel Cancer Center 28
Testing effectiveness (Phase 2)Ended earlyNCT05256381
What this trial is testing

SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerColorectal CancerCutaneous Squamous Cell Carcinoma+3 more
SOTIO Biotech AG 166
Testing effectiveness (Phase 2)Looking for participantsNCT06580054
What this trial is testing

Pembrolizumab for the Treatment of Locally Advanced and/or Recurrent Orbital or Periocular Cutaneous Squamous Cell Carcinoma

Who this might be right for
Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and NeckRecurrent Cutaneous Squamous Cell Carcinoma of the Head and NeckStage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
University of Michigan Rogel Cancer Center 22
Early research (Phase 1)WithdrawnNCT05220748
What this trial is testing

RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCC

Who this might be right for
Cutaneous Squamous Cell CarcinomaHead and Neck Squamous Cell Carcinoma
Rakuten Medical, Inc.
Testing effectiveness (Phase 2)Active Not RecruitingNCT04050436
What this trial is testing

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer

Who this might be right for
Cutaneous Squamous Cell CarcinomaAdvanced Cutaneous Squamous Cell CarcinomaMetastatic Cutaneous Squamous Cell Carcinoma
Replimune Inc. 231
Testing effectiveness (Phase 2)Ended earlyNCT01984892
What this trial is testing

Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC)

Who this might be right for
MelanomaSquamous Cell Carcinoma of the Head and NeckSquamous Cell Carcinoma of the Skin+3 more
Nina Bhardwaj 8
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