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Results for “Advanced Dedifferentiated Liposarcoma”

28 trials

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Showing 20 of 28 results

Early research (Phase 1)Looking for participantsNCT05711615
What this trial is testing

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Who this might be right for
Metastatic Dedifferentiated LiposarcomaMetastatic LeiomyosarcomaMetastatic Myxofibrosarcoma+9 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Looking for participantsNCT06789172
What this trial is testing

A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors

Who this might be right for
Solid TumoursSarcomaHNSCC+9 more
Epkin 166
Large-scale testing (Phase 3)Study completedNCT02606461
What this trial is testing

Selinexor in Advanced Liposarcoma

Who this might be right for
Dedifferentiated Liposarcoma
Karyopharm Therapeutics Inc 342
Large-scale testing (Phase 3)Active Not RecruitingNCT04967521
What this trial is testing

SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

Who this might be right for
Advanced Dedifferentiated Liposarcoma
Sarcoma Alliance for Research through Collaboration 108
Testing effectiveness (Phase 2)Active Not RecruitingNCT05886634
What this trial is testing

Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

Who this might be right for
Dedifferentiated LiposarcomaSoft Tissue SarcomaSarcoma,Soft Tissue+4 more
Memorial Sloan Kettering Cancer Center 16
Testing effectiveness (Phase 2)UnknownNCT02571829
What this trial is testing

A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Who this might be right for
LiposarcomaSoft Tissue Sarcoma
Hadassah Medical Organization 30
Testing effectiveness (Phase 2)Ended earlyNCT05116683
What this trial is testing

ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma

Who this might be right for
LeiomyosarcomaLiposarcoma
Benjamin Izar 4
Large-scale testing (Phase 3)Study completedNCT06058793
What this trial is testing

Brightline-4: A Study to Test How Well Brigimadlin is Tolerated by People With a Type of Cancer Called Dedifferentiated Liposarcoma

Who this might be right for
Liposarcoma, Dedifferentiated
Boehringer Ingelheim 138
Testing effectiveness (Phase 2)Study completedNCT02500797
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Who this might be right for
Locally Advanced Bone SarcomaLocally Advanced Dedifferentiated LiposarcomaLocally Advanced Gastrointestinal Stromal Tumor+18 more
National Cancer Institute (NCI) 164
Testing effectiveness (Phase 2)Active Not RecruitingNCT04438824
What this trial is testing

Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

Who this might be right for
Well-differentiated/Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center 42
Testing effectiveness (Phase 2)Looking for participantsNCT06498648
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

Who this might be right for
Advanced Dedifferentiated LiposarcomaAdvanced LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI) 74
Testing effectiveness (Phase 2)WithdrawnNCT00969917
What this trial is testing

Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma

Who this might be right for
Dedifferentiated Liposarcoma
Infinity Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT02247544
What this trial is testing

Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma

Who this might be right for
LiposarcomaLeiomyosarcoma
Italian Sarcoma Group 105
Testing effectiveness (Phase 2)Looking for participantsNCT06389799
What this trial is testing

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)

Who this might be right for
Dedifferentiated Liposarcoma
Lund University Hospital 33
Testing effectiveness (Phase 2)UnknownNCT03096912
What this trial is testing

A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Who this might be right for
Liposarcomas, DedifferentiatedLiposarcoma - Well DifferentiatedLiposarcoma; Mixed Type+1 more
Assaf-Harofeh Medical Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05694871
What this trial is testing

Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma

Who this might be right for
Advanced Dedifferentiated LiposarcomaLocally Advanced Dedifferentiated LiposarcomaMetastatic Dedifferentiated Liposarcoma+3 more
Alliance for Clinical Trials in Oncology 77
Testing effectiveness (Phase 2)Ended earlyNCT05580588
What this trial is testing

Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas

Who this might be right for
Liposarcoma, Dedifferentiated
Shanghai Pharma Biotherapeutics USA Inc. 14
Early research (Phase 1)Study completedNCT04242238
What this trial is testing

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

Who this might be right for
SarcomaAdvanced SarcomaHigh Grade Sarcoma+4 more
Memorial Sloan Kettering Cancer Center 32
Early research (Phase 1)Ended earlyNCT03604783
What this trial is testing

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsSarcomaEwing Sarcoma+2 more
Sumitomo Pharma America, Inc. 74
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06694324
What this trial is testing

First-line Treatment of Advanced/unresectable DDLPS

Who this might be right for
Dedifferentiated LiposarcomaSoft Tissue Sarcoma (STS)
Fudan University 49
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