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Results for “Advanced Dedifferentiated Liposarcoma”

29 trials

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Showing 20 of 29 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03114527
What this trial is testing

Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

Who this might be right for
Soft Tissue Sarcoma
Fox Chase Cancer Center 48
Testing effectiveness (Phase 2)Ended earlyNCT01876043
What this trial is testing

Efficacy and Safety of Plitidepsin in Patients With Advanced Unresectable or Metastatic, Relapsed/Refractory, Dedifferentiated Liposarcoma (DLPS): an Exploratory Phase II Multicenter Trial

Who this might be right for
Adult Patients With Unresectable Locally Advanced or Metastatic, Relapsed/Refractory Dedifferentiated Liposarcoma
Institut Bergonié 24
Early research (Phase 1)Ended earlyNCT03604783
What this trial is testing

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsSarcomaEwing Sarcoma+2 more
Sumitomo Pharma America, Inc. 74
Large-scale testing (Phase 3)Study completedNCT05218499
What this trial is testing

Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma

Who this might be right for
Liposarcoma, Dedifferentiated
Boehringer Ingelheim 400
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06694324
What this trial is testing

First-line Treatment of Advanced/unresectable DDLPS

Who this might be right for
Dedifferentiated LiposarcomaSoft Tissue Sarcoma (STS)
Fudan University 49
Testing effectiveness (Phase 2)Looking for participantsNCT06975293
What this trial is testing

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

Who this might be right for
Solid TumorSarcomaLeiomyosarcoma+1 more
STORM Therapeutics LTD 107
Testing effectiveness (Phase 2)Active Not RecruitingNCT04438824
What this trial is testing

Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

Who this might be right for
Well-differentiated/Dedifferentiated Liposarcoma
Memorial Sloan Kettering Cancer Center 42
Large-scale testing (Phase 3)Study completedNCT02606461
What this trial is testing

Selinexor in Advanced Liposarcoma

Who this might be right for
Dedifferentiated Liposarcoma
Karyopharm Therapeutics Inc 342
Testing effectiveness (Phase 2)UnknownNCT03096912
What this trial is testing

A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Who this might be right for
Liposarcomas, DedifferentiatedLiposarcoma - Well DifferentiatedLiposarcoma; Mixed Type+1 more
Assaf-Harofeh Medical Center 30
Testing effectiveness (Phase 2)UnknownNCT02571829
What this trial is testing

A Phase II Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Who this might be right for
LiposarcomaSoft Tissue Sarcoma
Hadassah Medical Organization 30
Early research (Phase 1)Looking for participantsNCT05607095
What this trial is testing

LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, or Dedifferentiated Liposarcoma

Who this might be right for
Uveal MelanomaMelanomaMetastatic Uveal Melanoma+1 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06578624
What this trial is testing

Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor
Lamassu Bio Inc 70
Testing effectiveness (Phase 2)Looking for participantsNCT06843967
What this trial is testing

Mirdametinib in Combination With Palbociclib in People With Liposarcoma

Who this might be right for
Well Differentiated LiposarcomaDedifferentiated LiposarcomaLiposarcoma+6 more
Memorial Sloan Kettering Cancer Center 54
Large-scale testing (Phase 3)Active Not RecruitingNCT04967521
What this trial is testing

SARC041: Study of Abemaciclib Versus Placebo in Patients with Advanced Dedifferentiated Liposarcoma

Who this might be right for
Advanced Dedifferentiated Liposarcoma
Sarcoma Alliance for Research through Collaboration 108
Testing effectiveness (Phase 2)Study completedNCT02500797
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Who this might be right for
Locally Advanced Bone SarcomaLocally Advanced Dedifferentiated LiposarcomaLocally Advanced Gastrointestinal Stromal Tumor+18 more
National Cancer Institute (NCI) 164
Testing effectiveness (Phase 2)Study completedNCT02247544
What this trial is testing

Efficacy Study on Trabectedin in Retroperitoneal Leiomyosarcoma and Well Differentiated/Dedifferentiated Liposarcoma

Who this might be right for
LiposarcomaLeiomyosarcoma
Italian Sarcoma Group 105
Testing effectiveness (Phase 2)Looking for participantsNCT06389799
What this trial is testing

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)

Who this might be right for
Dedifferentiated Liposarcoma
Lund University Hospital 33
Testing effectiveness (Phase 2)Looking for participantsNCT06498648
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

Who this might be right for
Advanced Dedifferentiated LiposarcomaAdvanced LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI) 74
Testing effectiveness (Phase 2)Ended earlyNCT05580588
What this trial is testing

Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas

Who this might be right for
Liposarcoma, Dedifferentiated
Shanghai Pharma Biotherapeutics USA Inc. 14
Early research (Phase 1)Study completedNCT04242238
What this trial is testing

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

Who this might be right for
SarcomaAdvanced SarcomaHigh Grade Sarcoma+4 more
Memorial Sloan Kettering Cancer Center 32
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