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Results for “Advanced Digestive System Carcinoma”

2,550 trials

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Showing 20 of 2,550 results

Early research (Phase 1)Looking for participantsNCT06723236
What this trial is testing

MGC028 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNSCLC AdenocarcinomaCholangiocarcinoma+2 more
MacroGenics 124
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Not applicableUnknownNCT06349044
What this trial is testing

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Who this might be right for
Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric AdenocarcinomaHepatocellular CarcinomaBiliary Tract Carcinoma+1 more
Zhejiang Cancer Hospital 120
Testing effectiveness (Phase 2)Looking for participantsNCT04150744
What this trial is testing

RFA Plus Carrizumab vs Carrizumab Alone for HCC

Who this might be right for
Tumor ImmunityImmunosuppressionRadiofrequency Ablation
Second Affiliated Hospital, Zhejiang University, School of Medicine 120
Early research (Phase 1)Study completedNCT03132792
What this trial is testing

AFPᶜ³³²T in Advanced HCC

Who this might be right for
Hepatocellular CancerAFP Expressing Tumors
Adaptimmune 39
Testing effectiveness (Phase 2)Looking for participantsNCT07246668
What this trial is testing

A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaLiver NeoplasmsCarcinoma+1 more
Yonsei University 52
Large-scale testing (Phase 3)UnknownNCT03794440
What this trial is testing

Evaluate the Efficacy and Safety of Sintilimab in Combination With IBI305 (Anti-VEGF Monoclonal Antibody) Compared to Sorafenib as the First-Line Treatment for Advanced Hepatocellular Carcinoma.

Who this might be right for
Hepatocellular Carcinoma
Innovent Biologics (Suzhou) Co. Ltd. 595
Testing effectiveness (Phase 2)Study completedNCT01258608
What this trial is testing

Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Human Genome Sciences Inc., a GSK Company 101
Testing effectiveness (Phase 2)Study completedNCT00002608
What this trial is testing

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Who this might be right for
Adrenocortical CarcinomaBrain and Central Nervous System TumorsHead and Neck Cancer+4 more
Ottawa Regional Cancer Centre 30
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Testing effectiveness (Phase 2)WithdrawnNCT06090318
What this trial is testing

Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss

Who this might be right for
Advanced Solid TumorCDKN2ANSCLC+7 more
Rain Oncology Inc
Testing effectiveness (Phase 2)Study completedNCT02335918
What this trial is testing

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)Ovarian Carcinoma-Enrollment CompletedColorectal Cancer (CRC)-Enrollment Completed+2 more
Celldex Therapeutics 175
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)UnknownNCT01308645
What this trial is testing

Evaluating the Safety and Efficacy of SB Injection in Patients With Advanced or Primary Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
SBPharmaceutical IND, Co., LTD 30
Early research (Phase 1)Study completedNCT01975831
What this trial is testing

Evaluate MEDI4736 in Combination With Tremelimumab

Who this might be right for
Breast CancerOvarian CancerColorectal Cancer+2 more
Ludwig Institute for Cancer Research 104
Large-scale testing (Phase 3)Not Yet RecruitingNCT07653451
What this trial is testing

Precision Medicine for Immunotherapy-Resistant Advanced Esophageal Cancer

Who this might be right for
Esophageal Squamous Cell Carcinoma
Peking University Cancer Hospital & Institute 90
Early research (Phase 1)Ended earlyNCT06466187
What this trial is testing

SGN-MesoC2 in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungOvarian NeoplasmsPancreatic Adenocarcinoma+4 more
Seagen, a wholly owned subsidiary of Pfizer 19
Testing effectiveness (Phase 2)Ended earlyNCT05188209
What this trial is testing

Evaluate the Efficacy and Safety of MRG003 in Patients With Advanced Gastric Cancer.

Who this might be right for
Advanced or Metastatic Gastric CancerAdvanced or Metastatic Gastroesophageal Junction Carcinoma
Lepu Biopharma Co., Ltd. 6
Large-scale testing (Phase 3)UnknownNCT02319187
What this trial is testing

Irinotecan Plus S1 Versus S1 in Patients With Previously Treated Advanced Esophageal Cancer: ESWN 01 Trial

Who this might be right for
Esophageal Neoplasms
Chinese Academy of Medical Sciences 240
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