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Results for “Advanced Digestive System Neuroendocrine Neoplasm”

356 trials

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Showing 20 of 356 results

Early research (Phase 1)Study completedNCT03629756
What this trial is testing

Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies

Who this might be right for
Non-small Cell Lung CancerSquamous Cell Carcinoma of the Head and NeckBreast Cancer+9 more
Arcus Biosciences, Inc. 48
Not applicableStudy completedNCT04670445
What this trial is testing

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer

Who this might be right for
Stage IV MelanomaAdvanced Lung CancerStage IV Non-Small Cell Lung Cancer+19 more
Massachusetts General Hospital 199
Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Not applicableNot Yet RecruitingNCT07689812
What this trial is testing

Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Carcinoma)+12 more
Natera, Inc. 920
Early research (Phase 1)Study completedNCT03000257
What this trial is testing

Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
AbbVie 182
Very early researchUnknownNCT05961111
What this trial is testing

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors

Who this might be right for
SarcomaCarcinomaDigestive Cancer+7 more
Shanghai Yunying Medical Technology 20
Early research (Phase 1)Study completedNCT00375245
What this trial is testing

Rapamycin With Grapefruit Juice for Advanced Malignancies

Who this might be right for
TumorsNeoplasm Metastasis
University of Chicago 41
Testing effectiveness (Phase 2)Study completedNCT02955069
What this trial is testing

Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)

Who this might be right for
Well-differentiated Non-functional NET of Thoracic OriginWell-differentiated Non-functional NET of Gastrointestinal OriginWell-differentiated Non-functional NET of Pancreatic Origin+1 more
Novartis Pharmaceuticals
Early research (Phase 1)Ended earlyNCT04042480
What this trial is testing

SGN-CD228A in Advanced Solid Tumors

Who this might be right for
Cutaneous MelanomaPleural MesotheliomaHER2 Negative Breast Neoplasms+3 more
Seagen Inc. 88
Testing effectiveness (Phase 2)Study completedNCT02611024
What this trial is testing

Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors

Who this might be right for
Advanced Solid TumorsGlioblastomaSoft Tissue Sarcoma (Excluding GIST)+9 more
PharmaMar 316
Early research (Phase 1)Study completedNCT00049023
What this trial is testing

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsGastrointestinal Carcinoid TumorIslet Cell Tumor+4 more
O'Dorisio, M S 27
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Early research (Phase 1)Study completedNCT01183663
What this trial is testing

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 180
Testing effectiveness (Phase 2)Looking for participantsNCT05824975
What this trial is testing

Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorSoft Tissue Sarcoma (STS)+6 more
GI Innovation, Inc. 358
Post-approval studies (Phase 4)Looking for participantsNCT07405086
What this trial is testing

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Hepatocellular Carcinoma+18 more
OHSU Knight Cancer Institute 160
Early research (Phase 1)Ended earlyNCT02961283
What this trial is testing

Study of ASN003 in Subjects With Advanced Solid Tumors

Who this might be right for
NeoplasmsMelanomaColorectal Neoplasm+1 more
Asana BioSciences 24
Early research (Phase 1)Ended earlyNCT02012231
What this trial is testing

Phase I/IIa Study to Evaluate the Safety, PK, PD, and Preliminary Efficacy of PLX8394 in Patients With Advanced Cancers.

Who this might be right for
MelanomaThyroid CancerColorectal Cancer+4 more
Fore Biotherapeutics 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT05688280
What this trial is testing

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS

Who this might be right for
Metastatic Solid TumorColon CancerNonsmall Cell Lung Cancer+1 more
Immunophotonics, Inc. 42
Testing effectiveness (Phase 2)Ended earlyNCT03435640
What this trial is testing

REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies

Who this might be right for
MelanomaMerkel Cell CarcinomaTriple Negative Breast Cancer+4 more
Nektar Therapeutics 64
Testing effectiveness (Phase 2)Ended earlyNCT01374451
What this trial is testing

Efficacy of Everolimus Alone or in Combination With Pasireotide LAR in Advanced PNET

Who this might be right for
Islet Cell Tumor
Novartis Pharmaceuticals 160
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