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Results for “Advanced Digestive System Tumor”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT05877599
What this trial is testing

NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Who this might be right for
Non-small Cell Lung CancerHead and Neck Squamous Cell CarcinomaColorectal Carcinoma+5 more
AstraZeneca 45
Large-scale testing (Phase 3)Looking for participantsNCT07221149
What this trial is testing

Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

Who this might be right for
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Bristol-Myers Squibb 690
Testing effectiveness (Phase 2)UnknownNCT04229849
What this trial is testing

Anrotenib Plus Toripalimab Versus Toripalimab in Patients With Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
Henan Cancer Hospital 164
Testing effectiveness (Phase 2)Study completedNCT00002955
What this trial is testing

Combination Chemotherapy in Treating Patients With Advanced Cancer of the Pancreas

Who this might be right for
Pancreatic Cancer
University of Southern California 21
Large-scale testing (Phase 3)Looking for participantsNCT06925243
What this trial is testing

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])Neoadjuvant TherapyAdjuvant Chemotherapy+3 more
Zuoyi Jiao 682
Testing effectiveness (Phase 2)Study completedNCT03058289
What this trial is testing

A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6

Who this might be right for
Breast CancerHead and Neck CancerSquamous Cell Carcinoma+8 more
Intensity Therapeutics, Inc. 111
Early research (Phase 1)UnknownNCT06300489
What this trial is testing

Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Zhejiang Cancer Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Early research (Phase 1)Study completedNCT04672460
What this trial is testing

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsSolid TumorsOvarian Cancer+5 more
Pfizer 73
Testing effectiveness (Phase 2)Study completedNCT03602079
What this trial is testing

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Who this might be right for
HER2-positive Breast CancerHER2 Gene MutationHER-2 Gene Amplification+41 more
Klus Pharma Inc. 49
Early research (Phase 1)Study completedNCT01337050
What this trial is testing

Asian Phase I Study Of PF-03446962

Who this might be right for
Neoplasms
Pfizer 36
Testing effectiveness (Phase 2)WithdrawnNCT01859182
What this trial is testing

Selumetinib and Akt Inhibitor MK-2206 in Treating Patients With Refractory or Advanced Gallbladder or Bile Duct Cancer That Cannot Be Removed By Surgery

Who this might be right for
Adenocarcinoma of the GallbladderAdenocarcinoma With Squamous Metaplasia of the GallbladderAdult Primary Cholangiocellular Carcinoma+12 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT01677559
What this trial is testing

Combining MLN8237 With Nab-Paclitaxel in Patients With Advanced Solid Malignancies

Who this might be right for
AdenocarcinomaPancreatic Neoplasms
Washington University School of Medicine 34
Not applicableStudy completedNCT04540159
What this trial is testing

Immune Checkpoints in Intraabdominal Ascites Fluid

Who this might be right for
Colorectal Cancer
Istanbul Training and Research Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT04644068
What this trial is testing

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

Who this might be right for
Ovarian CancerBreast CancerPancreatic Cancer+10 more
AstraZeneca 702
Testing effectiveness (Phase 2)Looking for participantsNCT03516708
What this trial is testing

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Washington University School of Medicine 49
Early research (Phase 1)Looking for participantsNCT07094113
What this trial is testing

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

Who this might be right for
KRAS Altered Advanced or Metastatic Solid Tumors
Amgen 434
Large-scale testing (Phase 3)Study completedNCT02746796
What this trial is testing

Study of ONO-4538 in Gastric Cancer

Who this might be right for
Gastric Cancer
Ono Pharmaceutical Co., Ltd. 680
Testing effectiveness (Phase 2)Ended earlyNCT04808362
What this trial is testing

Phase 1/2 Study to Evaluate Safety, PK and Efficacy of the MYC-Inhibitor OMO-103 in Solid Tumours

Who this might be right for
Advanced Solid TumorsPancreatic CancerCRC
Peptomyc S.L. 22
Testing effectiveness (Phase 2)Study completedNCT00059982
What this trial is testing

Perifosine in Treating Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Eastern Cooperative Oncology Group
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