Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Disease”

17,172 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 17,172 results

Early research (Phase 1)UnknownNCT04448379
What this trial is testing

Efficacy and Safety of JMT101 Combined With Afatinib (or Osimertinib) in Patients With Non-Small Cell Lung Cancer

Who this might be right for
Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Shanghai JMT-Bio Inc. 48
Not applicableStudy completedNCT00865046
What this trial is testing

Periosteal Stimulation for Knee Osteoarthritis

Who this might be right for
Osteoarthritis, Knee
US Department of Veterans Affairs 190
Testing effectiveness (Phase 2)Study completedNCT04181788
What this trial is testing

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

Who this might be right for
Advanced MalignanciesNon-small-cell Lung Cancer
Pfizer 155
Testing effectiveness (Phase 2)Active Not RecruitingNCT04792073
What this trial is testing

Study of Avelumab and/or Radiation Therapy in People With Advanced Merkel Cell Carcinoma

Who this might be right for
Merkel Cell Carcinoma
Memorial Sloan Kettering Cancer Center 18
Early research (Phase 1)UnknownNCT03217669
What this trial is testing

Epacadostat (INCB24360) in Combination With Sirolimus in Advanced Malignancy

Who this might be right for
Advanced Solid TumorNon-small Cell Lung Cancer (NSCLC)
Chao Huang 15
Not applicableStudy completedNCT07645183
What this trial is testing

Advanced Technology for Myopia Control in Children and Young Adults

Who this might be right for
Myopia (Disorder)Refraction Error
University of Faisalabad 90
Testing effectiveness (Phase 2)WithdrawnNCT00256841
What this trial is testing

Hypo-Hyperfractionated Chest Radiation for Non Small Cell Lung Cancer With Taxotere/Xeloda Combination Chemotherapy

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Clinical Oncology Research Associates
Early research (Phase 1)Active Not RecruitingNCT07021066
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

Who this might be right for
Gastric AdenocarcinomaAdvanced Pancreatic Ductal AdenocarcinomaEsophageal Adenocarcinoma+2 more
SystImmune Inc. 160
Not applicableLooking for participantsNCT04850729
What this trial is testing

Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Nanfang Hospital, Southern Medical University 169
Testing effectiveness (Phase 2)Study completedNCT02400788
What this trial is testing

Resminostat (YHI-1001) in Combination With Sorafenib in Asian Patients With Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
Yakult Honsha Co., LTD 179
Testing effectiveness (Phase 2)Ended earlyNCT04375527
What this trial is testing

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC V8Clinical Stage IV Cutaneous Melanoma AJCC V8Locally Advanced Cutaneous Melanoma+8 more
Jonsson Comprehensive Cancer Center 3
Not applicableStudy completedNCT05292027
What this trial is testing

Neoadjuvant Chemotherapy and Low-dose Radiotherapy Sequential Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Sichuan Cancer Hospital and Research Institute 84
Testing effectiveness (Phase 2)Study completedNCT00027742
What this trial is testing

Temozolomide and Interferon Alfa in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Intraocular MelanomaMelanoma (Skin)
Memorial Sloan Kettering Cancer Center
Not applicableStudy completedNCT01725386
What this trial is testing

An Observational Study of Xeloda (Capecitabine) in Participants With Metastatic or Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 274
Not applicableUnknownNCT06433986
What this trial is testing

MCAT Versus VISTA With Volume Stable Collagen Matrix in RT3 Gingival Recession

Who this might be right for
Gingival Recession
Postgraduate Institute of Dental Sciences Rohtak 34
Early research (Phase 1)Study completedNCT02914470
What this trial is testing

Carboplatin-cyclophosphamide Combined With Atezolizumab

Who this might be right for
Breast CancerCervix CancerOvarian Cancer+1 more
The Netherlands Cancer Institute 12
Not applicableUnknownNCT04909073
What this trial is testing

Observational Study of Afatinib 30 mg Daily

Who this might be right for
Non-Small Cell Lung CancerEpidermal Growth Factor Receptor Mutation
National University Hospital, Singapore 69
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07658183
What this trial is testing

A Clinical Trial Comparing the Efficacy and Safety of Different Doses of BL0175 Injection in Treating Postmenopausal Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer (Locally Advanced or Metastatic)
Shanghai Best-Link Bioscience, LLC 120
Not applicableStudy completedNCT06726694
What this trial is testing

Class II Malocclusion Correction Using the Mini-screw Supported Advanced Molar Distalization Appliance

Who this might be right for
Class II Malocclusion
Ain Shams University 25
Early research (Phase 1)Study completedNCT03562494
What this trial is testing

VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)

Who this might be right for
Parkinson's Disease
Neurocrine Biosciences 14
Next Page