Testing effectiveness (Phase 2)UnknownNCT05866510What this trial is testingUtidelone and Anlotinib in Advanced Recurrent Metastatic Esophageal CancerWho this might be right forEsophageal Cancer Peking University 47
Early research (Phase 1)Study completedNCT04440943What this trial is testingThe PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced MalignanciesWho this might be right forNon-small Cell Lung CancerBreast CancerGastric Cancer+11 more Celldex Therapeutics 27
Large-scale testing (Phase 3)Study completedNCT02625610What this trial is testingAvelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)Who this might be right forUnresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction EMD Serono Research & Development Institute, Inc. 499
Post-approval studies (Phase 4)Ended earlyNCT02721550What this trial is testingA Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCCWho this might be right forEsophageal Neoplasms Shandong Cancer Hospital and Institute 2
Testing effectiveness (Phase 2)Looking for participantsNCT06885814What this trial is testingEfficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell CarcinomaWho this might be right forEsophageal Squamous Cell Carcinoma Nanfang Hospital, Southern Medical University 30
Not applicableUnknownNCT04074447What this trial is testingThe Efficacy of Immunodetection Point Inhibitors for Advanced Esophageal CancerWho this might be right forEsophageal Cancer Sun Yat-sen University 80
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06746961What this trial is testingEfficacy and Safety of QL1706 Plus Lenvatinib As 2nd Line Theapy in Patients with Metastatic Esophageal Carcinoma After Disease Progression on ICIs TherapyWho this might be right forEsophageal Squamous Cell Carcinoma (ESCC) The First Affiliated Hospital of Zhengzhou University 49
Early research (Phase 1)Ended earlyNCT05462873What this trial is testingInvestigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid TumorsWho this might be right forCarcinoma, Non-Small-Cell LungCarcinoma, Renal CellEsophageal Squamous Cell Carcinoma+1 more Novartis Pharmaceuticals 30
Early research (Phase 1)Study completedNCT00005842What this trial is testingTrastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic CancerWho this might be right forCancer National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07709533What this trial is testingAn Umbrella-designed Prospective Multicenter Randomized Open-label Superiority Trial Evaluating Multi-biomarker-guided Precision Therapy for First-line Treatment of Advanced Esophageal Squamous Cell CarcinomaWho this might be right forValid MeSH Conditions Sun Yat-sen University 347
Testing effectiveness (Phase 2)Study completedNCT03797625What this trial is testingEndostar Combined With IP Second-line Treatment of Advanced Esophageal Squamous Cell CarcinomasWho this might be right forEsophageal Squamous Cell Carcinoma Fudan University 52
Testing effectiveness (Phase 2)Looking for participantsNCT06421376What this trial is testingInduction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal CancerWho this might be right forEsophageal CancerImmunotherapyInduction Therapy+2 more Cancer Institute and Hospital, Chinese Academy of Medical Sciences 60
Not applicableUnknownNCT04759235What this trial is testingMultimodal Functional Imaging Combined With Metabolomics in Predicting the Efficacy of nCRT for Locally Advanced ESCCWho this might be right forEsophageal Squamous Cell Carcinoma RenJi Hospital 118
Early research (Phase 1)Not Yet RecruitingNCT05048368What this trial is testingPharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic FunctionWho this might be right forEsophageal CancerAdvanced Solid Tumor Sunshine Lake Pharma Co., Ltd. 32
Large-scale testing (Phase 3)Study completedNCT03933449What this trial is testingStudy of Pembrolizumab (MK-3475) Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal/Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)-China Extension StudyWho this might be right forEsophageal CarcinomaEsophagogastric Junction Carcinoma Merck Sharp & Dohme LLC 123
Large-scale testing (Phase 3)UnknownNCT02773524What this trial is testingRegorafenib in Refractory Advanced Gastro-Oesophageal CancerWho this might be right forGastro-Oesophageal Cancer Australasian Gastro-Intestinal Trials Group 250
Early research (Phase 1)Ended earlyNCT04171141What this trial is testingStudy to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors.Who this might be right forGastrointestinal TumorsColorectal AdenocarcinomasGastric Adenocarcinomas+1 more Pfizer 79
Not applicableStudy completedNCT05142709What this trial is testingReal-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.Who this might be right forMetastatic Esophageal Squamous Cell Carcinoma Fudan University 1,197
Early research (Phase 1)Looking for participantsNCT07179692What this trial is testingCEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid TumorsWho this might be right forLung CancerGastric CancerColon Cancer+3 more Chongqing Precision Biotech Co., Ltd 108
Testing effectiveness (Phase 2)Study completedNCT00354679What this trial is testingIrinotecan, Cisplatin, Bevacizumab, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Esophageal CancerWho this might be right forEsophageal Cancer Memorial Sloan Kettering Cancer Center 34