Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced HCC Treated by Systemic Immunotherapy”

19 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 19 of 19 results

Not applicableEnrolling By InvitationNCT06773260
What this trial is testing

Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCC

Who this might be right for
Hepatocellular CarcinomaLiver CirrhosisPortal Hypertension
Azienda Ospedaliero Universitaria Policlinico Modena 150
Not applicableLooking for participantsNCT07273708
What this trial is testing

Identification of an Immune Single Cell Transcriptomic Profile of Responder and Non-responder Hepatocellular Carcinoma Patients Treated With Immune-checkpoint Inhibitors

Who this might be right for
Advanced HCC Treated by Systemic Immunotherapy
Fondazione IRCCS Policlinico San Matteo di Pavia 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT06680258
What this trial is testing

TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy

Who this might be right for
Hepatocellular Carcinoma (HCC)
Tempest Therapeutics 740
Testing effectiveness (Phase 2)Study completedNCT02509507
What this trial is testing

Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611

Who this might be right for
Hepatocellular CarcinomaLiver MetastasesCutaneous or Subcutaneous Lymph Node+1 more
Amgen 127
Early research (Phase 1)Study completedNCT03347292
What this trial is testing

Regorafenib Plus Pembrolizumab in First Line Systemic Treatment of HCC

Who this might be right for
Carcinoma, Hepatocellular
Bayer 58
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07187284
What this trial is testing

EDN Combined With TACE/HAIC and Second-Line Immune-Targeted Treatment Versus TACE/HAIC Alone in Locally Advanced HCC With Portal Vein Tumor Thrombosis After First-Line Therapy Failure: A Prospective, Multicenter, Randomized Controlled Trial

Who this might be right for
HCC - Hepatocellular Carcinoma
Zhongda Hospital 62
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Not applicableLooking for participantsNCT06349044
What this trial is testing

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Who this might be right for
Her-2 Negative Adenocarcinoma of the Gastro-oesophageal Junction/Gastric AdenocarcinomaHepatocellular CarcinomaBiliary Tract Carcinoma+1 more
Zhejiang Cancer Hospital
Large-scale testing (Phase 3)UnknownNCT00079027
What this trial is testing

Doxorubicin By Infusion or Chemoembolization in Treating Patients With Advanced Unresectable Hepatocellular Carcinoma (Liver Cancer)

Who this might be right for
Liver Cancer
University Hospital Birmingham 280
Testing effectiveness (Phase 2)Study completedNCT00484211
What this trial is testing

Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
AGC Biologics S.p.A. 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07192848
What this trial is testing

Adebrelimab + Apatinib in Advanced HCC Post-Systemic Therapy

Who this might be right for
Hepatocellular Carcinoma Non-resectable
Song Peng 47
Testing effectiveness (Phase 2)Study completedNCT03439891
What this trial is testing

Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v7+4 more
Robin Kate Kelley 16
Not applicableStudy completedNCT05729230
What this trial is testing

PAtient-PHYsician Relationship Assessment

Who this might be right for
Hepatocellular Carcinoma
Erasme University Hospital 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05975463
What this trial is testing

Hepatic Artery Infusion of Adebrelimab Combined With Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma With Failure of Systemic Therapy Combined With Interventional Therapy

Who this might be right for
Hepatocellular Carcinoma
HuiKai Li 30
Not applicableStudy completedNCT05197504
What this trial is testing

Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Systemic Therapy

Who this might be right for
Hepatocellular Carcinoma
CHA University 166
Not applicableStudy completedNCT05580809
What this trial is testing

CT Perfusion Parameters for Advanced HCC Treated by Systemic Immunotherapy

Who this might be right for
Advanced HCC Treated by Systemic Immunotherapy
Valérie LAURENT 9
Large-scale testing (Phase 3)Looking for participantsNCT06109272
What this trial is testing

Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma
AbbVie 660
Testing effectiveness (Phase 2)Study completedNCT03516071
What this trial is testing

Brivanib in Chinese Patients With Previously Treated Advanced HCC

Who this might be right for
Hepatocellular Carcinoma (HCC)
Zai Lab (Shanghai) Co., Ltd. 90
Large-scale testing (Phase 3)Looking for participantsNCT07166406
What this trial is testing

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8
NRG Oncology 252
120