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Results for “Advanced Hematological Malignancies”

295 trials

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Showing 20 of 295 results

Early research (Phase 1)Study completedNCT01139151
What this trial is testing

4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 31
Testing effectiveness (Phase 2)Study completedNCT02383927
What this trial is testing

Phase II Study of Tipifarnib in Squamous Head and Neck Cancer With HRAS Mutations

Who this might be right for
Thyroid CancerSquamous Cell Carcinoma Head and Neck Cancer (HNSCC)HRAS Mutant Tumor+1 more
Kura Oncology, Inc. 63
Early research (Phase 1)Study completedNCT00948467
What this trial is testing

Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies

Who this might be right for
Advanced Non-hematologic MalignanciesAdvanced Metastatic Melanoma
Millennium Pharmaceuticals, Inc. 51
Testing effectiveness (Phase 2)Ended earlyNCT00861965
What this trial is testing

Bioengineered Allogeneic Immune Cells (AlloStim) Not Requiring HLA Donor Match for Blood Cancers

Who this might be right for
Advanced or Refractory Leukemia, Lymphoma, Multiple Myeloma
Mirror Biologics, Inc. 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439357
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 4
Early research (Phase 1)Study completedNCT00867230
What this trial is testing

FTS Study in Patients With Advanced Hematologic Malignancies

Who this might be right for
Myelodysplastic SyndromeLeukemia
M.D. Anderson Cancer Center 18
Not applicableStudy completedNCT02992171
What this trial is testing

Primary Palliative Care for Patients With Advanced Hematologic Malignancies

Who this might be right for
Advanced Cancer
University of Pittsburgh 60
Testing effectiveness (Phase 2)Looking for participantsNCT04068597
What this trial is testing

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

Who this might be right for
Haematological MalignancyAcute Myeloid LeukemiaNon Hodgkin Lymphoma+3 more
CellCentric Ltd. 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439279
What this trial is testing

Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Early research (Phase 1)Looking for participantsNCT07195916
What this trial is testing

Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Who this might be right for
Solid TumorsHematologic Malignancies
Incyte Corporation 280
Early research (Phase 1)Active Not RecruitingNCT06645886
What this trial is testing

Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies

Who this might be right for
Hematologic MalignanciesAdult
Kumquat Biosciences Inc. 13
Not applicableNot Yet RecruitingNCT07234630
What this trial is testing

Role of Fibrinolytic Activity in Neoplastic Pathologies Complicated by Coagulopathy

Who this might be right for
Hematologic NeoplasmsSolid Tumor Metastatic Cancer Advanced CancerDisseminated Intravascular Coagulation
University Hospital, Strasbourg, France 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439136
What this trial is testing

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06303167
What this trial is testing

Testing AZD9291 as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH-Subprotocol E)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 19
Very early researchUnknownNCT04700319
What this trial is testing

CAR-T CD19/CD20 for Patients With Advanced CD19/CD20+ B Cell Line Recurrent or Refractory Hematological Malignancies

Who this might be right for
CAR
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 30
Large-scale testing (Phase 3)Active Not RecruitingNCT04939090
What this trial is testing

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Who this might be right for
Advanced Malignant Solid NeoplasmAnorexiaHematopoietic and Lymphoid Cell Neoplasm
Alliance for Clinical Trials in Oncology 227
Early research (Phase 1)Temporarily pausedNCT02333162
What this trial is testing

Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant

Who this might be right for
Previously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Adult Acute Myeloid Leukemia+1 more
University of Chicago 30
Early research (Phase 1)Study completedNCT01324323
What this trial is testing

Influence of Rifampin on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer

Who this might be right for
Hematologic MalignancyMalignant Lymphoma
Celgene 14
Testing effectiveness (Phase 2)Looking for participantsNCT04984551
What this trial is testing

Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia

Who this might be right for
Advanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
M.D. Anderson Cancer Center 312
Early research (Phase 1)Ended earlyNCT05609942
What this trial is testing

Study of Elenestinib (BLU-263) in Advanced Systemic Mastocytosis (AdvSM) and and Other KIT Altered Hematologic Malignancies

Who this might be right for
Advanced Systemic Mastocytosis
Blueprint Medicines Corporation 9
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