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Results for “Advanced Leiomyosarcoma”

97 trials

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Showing 20 of 97 results

Early research (Phase 1)Looking for participantsNCT05711615
What this trial is testing

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Who this might be right for
Metastatic Dedifferentiated LiposarcomaMetastatic LeiomyosarcomaMetastatic Myxofibrosarcoma+9 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT03277924
What this trial is testing

Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas

Who this might be right for
Soft Tissue SarcomaBone Sarcoma
Grupo Espanol de Investigacion en Sarcomas 197
Testing effectiveness (Phase 2)Looking for participantsNCT06528769
What this trial is testing

Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

Who this might be right for
LeiomyosarcomaSarcoma
Gabriel Tinoco 16
Testing effectiveness (Phase 2)Study completedNCT02428192
What this trial is testing

Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma

Who this might be right for
Metastatic LeiomyosarcomaUnresectable LeiomyosarcomaUterine Corpus Leiomyosarcoma
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT06638931
What this trial is testing

Agnostic Therapy in Rare Solid Tumors

Who this might be right for
Urachal CancerParathyroid CarcinomaFibrolamellar Carcinoma+38 more
Instituto do Cancer do Estado de São Paulo 28
Testing effectiveness (Phase 2)Study completedNCT00041236
What this trial is testing

Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma

Who this might be right for
Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC 39
Early research (Phase 1)Study completedNCT03009201
What this trial is testing

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Who this might be right for
Advanced Soft Tissue SarcomaLocally Advanced AngiosarcomaLocally Advanced Leiomyosarcoma+24 more
OHSU Knight Cancer Institute 16
Testing effectiveness (Phase 2)Study completedNCT00006357
What this trial is testing

STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma

Who this might be right for
Endometrial CancerGastrointestinal Stromal TumorOvarian Cancer+2 more
European Organisation for Research and Treatment of Cancer - EORTC 91
Early research (Phase 1)Active Not RecruitingNCT05827614
What this trial is testing

Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications

Who this might be right for
Triple Negative Breast Cancer (TNBC)High Grade Serous Ovarian CarcinomaHigh Grade Endometrial Carcinoma+9 more
Boundless Bio 85
Testing effectiveness (Phase 2)Active Not RecruitingNCT03851614
What this trial is testing

Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors

Who this might be right for
Mismatch Repair Proficient Colorectal CancerPancreatic AdenocarcinomaLeiomyosarcoma
University Health Network, Toronto 90
Testing effectiveness (Phase 2)Study completedNCT00949325
What this trial is testing

Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma

Who this might be right for
Sarcoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 24
Testing effectiveness (Phase 2)Study completedNCT00064220
What this trial is testing

Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Sarcoma
Daiichi Sankyo
Not applicableStudy completedNCT00253383
What this trial is testing

Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients

Who this might be right for
Cancer
Dartmouth-Hitchcock Medical Center 329
Early research (Phase 1)Ended earlyNCT03670069
What this trial is testing

Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas

Who this might be right for
Metastatic LeiomyosarcomaMetastatic Synovial SarcomaMetastatic Undifferentiated Pleomorphic Sarcoma+15 more
Fred Hutchinson Cancer Center 27
Early research (Phase 1)Study completedNCT00720174
What this trial is testing

Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma

Who this might be right for
Adult AngiosarcomaAdult Desmoplastic Small Round Cell TumorAdult Epithelioid Sarcoma+32 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Study completedNCT00041249
What this trial is testing

Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

Who this might be right for
Gastrointestinal Stromal TumorSarcoma
European Organisation for Research and Treatment of Cancer - EORTC 64
Testing effectiveness (Phase 2)Study completedNCT02815995
What this trial is testing

Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes

Who this might be right for
Advanced and/or Metastatic Sarcoma
M.D. Anderson Cancer Center 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT03880019
What this trial is testing

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Who this might be right for
Stage III Uterine Corpus Leiomyosarcoma AJCC v8Stage IV Uterine Corpus Leiomyosarcoma AJCC v8Uterine Corpus Leiomyosarcoma
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Ended earlyNCT02601209
What this trial is testing

Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma

Who this might be right for
High Grade SarcomaMetastatic LeiomyosarcomaMetastatic Malignant Peripheral Nerve Sheath Tumor+16 more
National Cancer Institute (NCI) 151
Early research (Phase 1)Active Not RecruitingNCT06308419
What this trial is testing

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Who this might be right for
LeiomyosarcomaSoft-tissue Sarcomas
M.D. Anderson Cancer Center 18
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