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Results for “Advanced MDS”

185 trials

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Showing 20 of 185 results

Testing effectiveness (Phase 2)Study completedNCT00053287
What this trial is testing

Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Case Comprehensive Cancer Center 42
Early research (Phase 1)Study completedNCT00038051
What this trial is testing

Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyeloproliferative Disorders+1 more
M.D. Anderson Cancer Center 28
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Testing effectiveness (Phase 2)Study completedNCT00674479
What this trial is testing

INCB018424 in Patients With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphocytic LeukemiaMyelodysplastic Syndrome+1 more
M.D. Anderson Cancer Center 51
Testing effectiveness (Phase 2)Active Not RecruitingNCT02935361
What this trial is testing

Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
University of Southern California 33
Early research (Phase 1)Study completedNCT00042900
What this trial is testing

Pyroxamide in Treating Patients With Advanced Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+5 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Active Not RecruitingNCT04603001
What this trial is testing

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+1 more
Eli Lilly and Company 260
Large-scale testing (Phase 3)Study completedNCT00005866
What this trial is testing

S9920 Busulfan Compared With Cyclophosphamide in Patients Undergoing Total-Body Irradiation Plus Peripheral Stem Cell Transplantation for Advanced Myelodysplastic Syndrome or Related Acute Myeloid Leukemia

Who this might be right for
LeukemiaMyelodysplastic Syndromes
SWOG Cancer Research Network 240
Testing effectiveness (Phase 2)Study completedNCT00014469
What this trial is testing

Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer

Who this might be right for
Graft Versus Host DiseaseLeukemiaMyelodysplastic Syndromes+1 more
Memorial Sloan Kettering Cancer Center
Early research (Phase 1)Study completedNCT00005967
What this trial is testing

Tipifarnib in Treating Patients With Advanced Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT03047993
What this trial is testing

Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Multilineage DysplasiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsBlasts 20-30 Percent of Peripheral Blood White Cells+4 more
M.D. Anderson Cancer Center 28
Early research (Phase 1)Study completedNCT01314599
What this trial is testing

Clinical Study of PM01183 in Patients With Acute Leukemia or Relapsed/Refractory Myelodysplastic Syndrome

Who this might be right for
Acute Leukemia
PharmaMar 45
Early research (Phase 1)Looking for participantsNCT05607199
What this trial is testing

A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

Who this might be right for
Solid Tumor, AdultAcute Myeloid LeukemiaMyelodysplastic Syndromes+1 more
Aurigene Discovery Technologies Limited 80
Testing effectiveness (Phase 2)Ended earlyNCT02089230
What this trial is testing

MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 19
Early research (Phase 1)Study completedNCT03573310
What this trial is testing

JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Who this might be right for
NeoplasmsSolid Tumor, AdultNon-Hodgkin Lymphoma+1 more
Janssen Research & Development, LLC 114
Early research (Phase 1)WithdrawnNCT02487459
What this trial is testing

Safety Study of Gene Modified Donor T-Cells in Adults With Advanced Hematologic Malignancies

Who this might be right for
Hematologic Malignancies
Bellicum Pharmaceuticals
Early research (Phase 1)Study completedNCT00380653
What this trial is testing

Safety and Pharmacology Study of Sapacitabine to Treat Advanced Leukemias or Myelodysplastic Syndromes

Who this might be right for
LeukemiasMyelodysplastic Syndromes
Cyclacel Pharmaceuticals, Inc. 47
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Ended earlyNCT01773395
What this trial is testing

GVAX vs. Placebo for MDS/AML After Allo HSCT

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia
Dana-Farber Cancer Institute 123
Testing effectiveness (Phase 2)Looking for participantsNCT07155226
What this trial is testing

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

Who this might be right for
Acute Lymphoblastic LeukaemiaAcute Myeloid LeukaemiaHigher-risk Myelodysplastic Syndromes
AstraZeneca 84
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