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Results for “Advanced Malignancies”

22,130 trials

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Showing 20 of 22,130 results

Not applicableLooking for participantsNCT06643000
What this trial is testing

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal MetastasisEGFR Gene Mutation
Henan Cancer Hospital 60
Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Early research (Phase 1)Study completedNCT05400265
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of HLX26 and HLX10 in Patients With Advanced/Metastatic Solid Tumor

Who this might be right for
Adult Solid Tumor
Shanghai Henlius Biotech 9
Not applicableNo Longer AvailableNCT03420430
What this trial is testing

Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of Care

Who this might be right for
Advanced Stage Cancer (Solid Tumor Disease for 4 Patients)Acute Myeloid Leukemia (6 Patients)
Genelux Corporation
Early research (Phase 1)Study completedNCT03883919
What this trial is testing

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Who this might be right for
Pancreatic CancerPancreas CancerCancer of the Pancreas
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06814067
What this trial is testing

Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaHead and Neck Squamous Cell Carcinoma HNSCC
Fudan University 80
Large-scale testing (Phase 3)Study completedNCT00026338
What this trial is testing

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
NCIC Clinical Trials Group 569
Testing effectiveness (Phase 2)Study completedNCT03200847
What this trial is testing

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

Who this might be right for
Stage IV MelanomaStage III MelanomaAdvanced Melanoma
University of Colorado, Denver 26
Testing effectiveness (Phase 2)Looking for participantsNCT07232849
What this trial is testing

A Trial of HRS-4508 Combined With Other Antitumor Therapies in Subjects With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Lung Cancer
Jiangsu HengRui Medicine Co., Ltd. 100
Not applicableActive Not RecruitingNCT04767594
What this trial is testing

First-line Palbociclib and Endocrine Therapy for Patients With HR+/HER2- Advanced Breast Cancer in the Real-world Setting.

Who this might be right for
Breast Neoplasms
Pfizer 1,409
Not applicableStudy completedNCT00460356
What this trial is testing

Glycoprotein and Glycan in Tissue and Blood Samples of Patients With Stage IB-IVA Cervical Cancer Undergoing Surgery to Remove Pelvic and Abdominal Lymph Nodes

Who this might be right for
Cervical AdenocarcinomaCervical Adenosquamous CarcinomaCervical Small Cell Carcinoma+6 more
Gynecologic Oncology Group 159
Early research (Phase 1)Study completedNCT00739453
What this trial is testing

Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®)

Who this might be right for
Advanced Solid Tumors
Astellas Pharma Inc 95
Testing effectiveness (Phase 2)Study completedNCT00810953
What this trial is testing

A Safety Study Using Pentamidine in Patients With Pancreatic Cancer Undergoing Standard Therapy

Who this might be right for
Pancreatic Cancer
Oncozyme Pharma Inc. 10
Early research (Phase 1)Study completedNCT05378737
What this trial is testing

Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8006 for Injection

Who this might be right for
Advanced Solid Tumors
Bio-Thera Solutions 216
Early research (Phase 1)Study completedNCT00056537
What this trial is testing

ABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic Cancer

Who this might be right for
Non-Small-Cell Lung CarcinomaRenal Cell CarcinomaPancreatic Cancer
Active Biotech AB 44
Early research (Phase 1)Active Not RecruitingNCT05174637
What this trial is testing

FDA018-ADC in Patients With Advanced Solid Tumors

Who this might be right for
Advanced/ Metastatic Solid Tumors
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 78
Early research (Phase 1)Study completedNCT01949545
What this trial is testing

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Solid TumorsHematologic MalignanciesHepatic Impairment
Amgen 46
Early research (Phase 1)Study completedNCT02897375
What this trial is testing

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors

Who this might be right for
Solid NeoplasmStage III Pancreatic CancerStage IIIA Breast Cancer+14 more
Emory University 71
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Study completedNCT00022477
What this trial is testing

BMS-247550 in Treating Patients With Recurrent or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Chicago 24
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