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Results for “Advanced Malignant Solid Tumor of Digestive System”

326 trials

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Showing 20 of 326 results

Not applicableUnknownNCT05952375
What this trial is testing

Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial

Who this might be right for
Gastric Cancer
The Affiliated Hospital of Qingdao University 9
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Early research (Phase 1)Active Not RecruitingNCT05163028
What this trial is testing

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

Who this might be right for
Non Small Cell Lung CancerColorectal CancerPancreatic Cancer+4 more
HUYABIO International, LLC. 42
Early research (Phase 1)Ended earlyNCT00585845
What this trial is testing

Study of Safety and Tolerability of Intravenous CRS-207 in Adults With Selected Advanced Solid Tumors Who Have Failed or Who Are Not Candidates for Standard Treatment

Who this might be right for
Malignant Epithelial MesotheliomaAdenocarcinoma of the PancreasCarcinoma, Non-Small-Cell Lung+1 more
Anza Therapeutics, Inc. 17
Early research (Phase 1)Study completedNCT00083213
What this trial is testing

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Cancer
Regeneron Pharmaceuticals 25
Testing effectiveness (Phase 2)Looking for participantsNCT03175224
What this trial is testing

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Who this might be right for
Solid TumorsAdvanced CancerRenal Cancer+15 more
Apollomics Inc. 497
Early research (Phase 1)Study completedNCT02227940
What this trial is testing

Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmALK PositiveMetastatic Pancreatic Adenocarcinoma+2 more
Roswell Park Cancer Institute 38
Early research (Phase 1)UnknownNCT02870036
What this trial is testing

Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics of Simmitecan Monotherapy and Combination in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced/Metastatic Colorectal Cancer
Haihe Biopharma Co., Ltd. 243
Early research (Phase 1)Not Yet RecruitingNCT07014878
What this trial is testing

DCTY1102 Injection in Participants With Advanced Solid Tumors

Who this might be right for
Colorectal CancerLung CancerPancreatic Cancer
Beijing DCTY Biotech Co.,Ltd. 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03682289
What this trial is testing

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Who this might be right for
Clear Cell Renal Cell CarcinomaLocally Advanced Pancreatic CancerLocally Advanced Malignant Solid Neoplasm+10 more
Rahul Aggarwal 83
Testing effectiveness (Phase 2)Active Not RecruitingNCT04440735
What this trial is testing

DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorNon Small Cell Lung CancerColorectal Cancer
Kahr Medical 125
Testing effectiveness (Phase 2)Looking for participantsNCT07749586
What this trial is testing

Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Arvinas Inc. 499
Early research (Phase 1)Study completedNCT05231746
What this trial is testing

HSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)

Who this might be right for
Advanced Solid Tumor
STCube, Inc. 47
Early research (Phase 1)Study completedNCT04306900
What this trial is testing

TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

Who this might be right for
Solid Tumor, Adult
Trishula Therapeutics, Inc. 185
Testing effectiveness (Phase 2)Study completedNCT00002608
What this trial is testing

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Who this might be right for
Adrenocortical CarcinomaBrain and Central Nervous System TumorsHead and Neck Cancer+4 more
Ottawa Regional Cancer Centre 30
Early research (Phase 1)Active Not RecruitingNCT05143970
What this trial is testing

First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors

Who this might be right for
Metastatic CancerMetastatic Breast CancerMetastatic Pancreatic Cancer+6 more
Institut Paoli-Calmettes 27
Early research (Phase 1)Ended earlyNCT05639153
What this trial is testing

A Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of DR30303 in Patients With Advanced Solid Tumors

Who this might be right for
Malignant Neoplasm of Digestive System
Zhejiang Doer Biologics Co., Ltd. 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT03157128
What this trial is testing

Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

Who this might be right for
Non-Small Cell Lung CancerMedullary Thyroid CancerColon Cancer+1 more
Eli Lilly and Company 857
Early research (Phase 1)Ended earlyNCT05346484
What this trial is testing

CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors

Who this might be right for
Solid TumorSolid CarcinomaSolid Tumor, Adult+4 more
Imugene Limited 66
Very early researchLooking for participantsNCT06380309
What this trial is testing

A Clinical Study on Evaluating Intravenous Administration of IDOV-SAFE

Who this might be right for
Advanced Malignant Solid Tumor of Digestive System
Peking University 89
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