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Results for “Advanced Malignant Solid Tumors”

824 trials

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Showing 20 of 824 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
Early research (Phase 1)Study completedNCT00732992
What this trial is testing

A Safety Study Of Sunitinib In Combination With Pemetrexed In Patients With Advanced Solid Malignancies

Who this might be right for
Neoplasm, Malignant
Pfizer 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439136
What this trial is testing

Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT02564900
What this trial is testing

Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Tumors
Daiichi Sankyo Co., Ltd. 292
Testing effectiveness (Phase 2)Study completedNCT00002608
What this trial is testing

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Who this might be right for
Adrenocortical CarcinomaBrain and Central Nervous System TumorsHead and Neck Cancer+4 more
Ottawa Regional Cancer Centre 30
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT02498613
What this trial is testing

Cediranib in Combination With Olaparib in Advanced Solid Tumors

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Lung Non-Small Cell CarcinomaMetastatic Lung Small Cell Carcinoma+23 more
National Cancer Institute (NCI) 122
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Early research (Phase 1)Active Not RecruitingNCT04521686
What this trial is testing

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

Who this might be right for
CholangiocarcinomaChondrosarcomaGlioma+1 more
Eli Lilly and Company 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Early research (Phase 1)Looking for participantsNCT07189195
What this trial is testing

TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmMetastatic Pancreatic Adenocarcinoma+5 more
University of California, Davis 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT05638295
What this trial is testing

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm
National Cancer Institute (NCI) 105
Early research (Phase 1)UnknownNCT05848999
What this trial is testing

UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Who this might be right for
Mesothelin-positive Advanced Malignant Solid Tumors
Zhejiang University 87
Early research (Phase 1)UnknownNCT04864379
What this trial is testing

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Who this might be right for
Advanced Malignant Solid Tumor
Sir Run Run Shaw Hospital 30
Not applicableUnknownNCT05949775
What this trial is testing

Clinical Study of mRNA Vaccine in Patients With Advanced Malignant Solid Tumors

Who this might be right for
Advanced Malignant Solid Tumors
Stemirna Therapeutics 20
Testing effectiveness (Phase 2)UnknownNCT05986981
What this trial is testing

MUC1 Therapeutic Tumor Vaccine in Advanced Solid Cancers

Who this might be right for
Solid Tumor, Adult
Peking Union Medical College Hospital 20
Early research (Phase 1)Study completedNCT01800630
What this trial is testing

Phase1 Study of Gemcitabine HCl Oral Formulation(D07001-F4) in Patients With Advanced Solid Malignancies and Malignant Lymphomas

Who this might be right for
Advanced Solid MalignanciesMalignant Lymphomas
InnoPharmax Inc. 37
Early research (Phase 1)WithdrawnNCT05010096
What this trial is testing

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the BoneMetastatic Malignant Solid Neoplasm+1 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
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