Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Advanced Malignant Thoracic Neoplasm”

306 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 306 results

Large-scale testing (Phase 3)Study completedNCT00128102
What this trial is testing

Suberoylanilide Hydroxamic Acid (Vorinostat, MK-0683) Versus Placebo in Advanced Malignant Pleural Mesothelioma (MK-0683-014)

Who this might be right for
MesotheliomaLung Cancer
Merck Sharp & Dohme LLC 661
Early research (Phase 1)Active Not RecruitingNCT03589339
What this trial is testing

NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

Who this might be right for
RadiotherapyImmunotherapyMicrosatellite Instability-High Solid Malignant Tumour+8 more
Nanobiotix 145
Not applicableLooking for participantsNCT06413212
What this trial is testing

Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing

Who this might be right for
Lung CancerBreast CancerGastric Cancer+1 more
Liu Huang 55
Large-scale testing (Phase 3)Study completedNCT00347412
What this trial is testing

Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Cellectar Biosciences, Inc. 903
Early research (Phase 1)Ended earlyNCT04042480
What this trial is testing

SGN-CD228A in Advanced Solid Tumors

Who this might be right for
Cutaneous MelanomaPleural MesotheliomaHER2 Negative Breast Neoplasms+3 more
Seagen Inc. 88
Testing effectiveness (Phase 2)Study completedNCT00003989
What this trial is testing

ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma

Who this might be right for
Lung CancerMelanoma (Skin)
European Organisation for Research and Treatment of Cancer - EORTC 50
Not applicableUnknownNCT06512896
What this trial is testing

Clinical Study on Intraluminal Injection of FOLactis

Who this might be right for
Solid TumorImmune ResponsePleural Effusion, Malignant+1 more
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 40
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Early research (Phase 1)Active Not RecruitingNCT03212404
What this trial is testing

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell LungCarcinoma, Small Cell+10 more
Checkpoint Therapeutics, Inc. 272
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Study completedNCT00017186
What this trial is testing

Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma

Who this might be right for
Malignant Mesothelioma
Alliance for Clinical Trials in Oncology 69
Early research (Phase 1)Study completedNCT00535951
What this trial is testing

Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma

Who this might be right for
Carcinoma, Non-Small-Cell LungMesothelioma
Novartis Pharmaceuticals 18
Early research (Phase 1)WithdrawnNCT06982222
What this trial is testing

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+4 more
National Cancer Institute (NCI)
Post-approval studies (Phase 4)Looking for participantsNCT07405086
What this trial is testing

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Hepatocellular Carcinoma+18 more
OHSU Knight Cancer Institute 160
Testing effectiveness (Phase 2)Study completedNCT00541073
What this trial is testing

Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgery

Who this might be right for
Malignant Mesothelioma
Centre Oscar Lambret 60
Not applicableUnknownNCT04263688
What this trial is testing

Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion

Who this might be right for
Non-Small Cell Lung Cancer
Guangzhou Institute of Respiratory Disease 300
Testing effectiveness (Phase 2)Looking for participantsNCT05188859
What this trial is testing

First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesothelioma

Who this might be right for
Mesothelioma, MalignantMesothelioma, Malignant PleuralMesothelioma Malignant Advanced
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 29
Early research (Phase 1)Ended earlyNCT05241873
What this trial is testing

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Who this might be right for
Lung Neoplasm MalignantCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+17 more
Blueprint Medicines Corporation 103
Testing effectiveness (Phase 2)Ended earlyNCT00003508
What this trial is testing

Antineoplaston Therapy in Treating Patients With Advanced Mesothelioma

Who this might be right for
Malignant Mesothelioma
Burzynski Research Institute 8
Testing effectiveness (Phase 2)Looking for participantsNCT06750185
What this trial is testing

Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 248
Next Page