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Results for “Advanced Merkel Cell Carcinoma”

71 trials

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Showing 20 of 71 results

Early research (Phase 1)WithdrawnNCT02831179
What this trial is testing

Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor

Who this might be right for
Functional Pancreatic Neuroendocrine TumorMalignant SomatostatinomaMerkel Cell Carcinoma+26 more
Vanderbilt-Ingram Cancer Center
Early research (Phase 1)Study completedNCT04242199
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more
Incyte Corporation 182
Testing effectiveness (Phase 2)Active Not RecruitingNCT03935893
What this trial is testing

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Who this might be right for
Gastric CancerColorectal CancerPancreatic Cancer+7 more
Udai Kammula 20
Large-scale testing (Phase 3)Looking for participantsNCT06947928
What this trial is testing

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

Who this might be right for
Advanced Or Metastatic Merkel Cell Carcinoma
TuHURA Biosciences, Inc. 118
Testing effectiveness (Phase 2)Study completedNCT02267603
What this trial is testing

Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer

Who this might be right for
Recurrent Merkel Cell CarcinomaStage III Merkel Cell Carcinoma AJCC v7Stage IIIA Merkel Cell Carcinoma AJCC v7+2 more
National Cancer Institute (NCI) 50
Not applicableEnded earlyNCT04106167
What this trial is testing

Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy

Who this might be right for
Advanced Solid TumorLymphomaGastric Cancer+15 more
Fate Therapeutics 20
Early research (Phase 1)Study completedNCT01155258
What this trial is testing

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Who this might be right for
Extensive Stage Small Cell Lung CancerHereditary ParagangliomaMale Breast Cancer+45 more
University of Southern California 19
Early research (Phase 1)Study completedNCT03458117
What this trial is testing

T-VEC in Non-melanoma Skin Cancer

Who this might be right for
Non-melanoma Skin CancerBasal Cell CarcinomaSquamous Cell Carcinoma+2 more
University of Zurich 26
Testing effectiveness (Phase 2)Study completedNCT03304639
What this trial is testing

Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma

Who this might be right for
Advanced Merkel Cell CarcinomaClinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8+5 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT03652077
What this trial is testing

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Who this might be right for
Cervical CancerGastric CancerStomach Cancer+18 more
Incyte Corporation 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07472322
What this trial is testing

ASTX727 & Retifanlimab-dlwr for Advanced Merkel Cell After Progression on Anti-PD-(L)1

Who this might be right for
Merkel Cell CarcinomaMerkel Cell Carcinoma, Stage IIIMerkel Cell Carcinoma, Stage IV
University of Wisconsin, Madison 31
Early research (Phase 1)Looking for participantsNCT04975152
What this trial is testing

Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 36
Early research (Phase 1)Study completedNCT04160065
What this trial is testing

Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaNon-Melanoma Skin Cancers
TuHURA Biosciences, Inc. 23
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Early research (Phase 1)Study completedNCT03000257
What this trial is testing

Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
AbbVie 182
Testing effectiveness (Phase 2)Ended earlyNCT04590781
What this trial is testing

Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer

Who this might be right for
Merkel Cell CarcinomaSmall Cell Lung Cancer
Xencor, Inc. 4
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Testing effectiveness (Phase 2)Study completedNCT04393753
What this trial is testing

Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1

Who this might be right for
Merkel Cell Carcinoma
4SC AG 19
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Testing effectiveness (Phase 2)Study completedNCT03241173
What this trial is testing

A Study Exploring the Safety and Efficacy of INCAGN01949 in Combination With Immune Therapies in Advanced or Metastatic Malignancies

Who this might be right for
Advanced Malignancies
Incyte Biosciences International Sàrl 52
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