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Results for “Advanced Metastatic Melanoma”

547 trials

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Showing 20 of 547 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Study completedNCT03548467
What this trial is testing

Evaluate Safety and Efficacy of Multiple Dosing With VB10.NEO and Bempegaldesleukin (NKTR-214) Immunotherapy in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
Locally Advanced or Metastatic Solid Tumours
Nykode Therapeutics ASA 41
Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
Testing effectiveness (Phase 2)Study completedNCT02768207
What this trial is testing

Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma

Who this might be right for
Metastatic Melanoma
Hoffmann-La Roche 40
Early research (Phase 1)Ended earlyNCT05573035
What this trial is testing

Investigate LYL845 in Adults With Solid Tumors

Who this might be right for
MelanomaNon-small Cell Lung CancerColorectal Cancer
Lyell Immunopharma, Inc. 39
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Early research (Phase 1)Active Not RecruitingNCT05176470
What this trial is testing

Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients

Who this might be right for
Locally Advanced MelanomaPathologic Stage IIIB Cutaneous Melanoma AJCC v8Pathologic Stage IIIC Cutaneous Melanoma AJCC v8+2 more
Richard Wu 2
Testing effectiveness (Phase 2)Study completedNCT05864144
What this trial is testing

SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultAdvanced Solid TumorHead and Neck Cancer+19 more
Sensei Biotherapeutics, Inc. 98
Early research (Phase 1)Study completedNCT00844064
What this trial is testing

Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2

Who this might be right for
Pancreatic NeoplasmsMelanomaColorectal Neoplasms
Isarna Therapeutics GmbH 62
Testing effectiveness (Phase 2)Study completedNCT02875132
What this trial is testing

Pembrolizumab in Advanced/Metastatic Acral Lentiginous Melanoma

Who this might be right for
Acral Lentiginous Melanoma
Chinese University of Hong Kong 9
Testing effectiveness (Phase 2)UnknownNCT04913337
What this trial is testing

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
MesotheliomaGlioblastomaRenal Cell Carcinoma+12 more
NGM Biopharmaceuticals, Inc 179
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT07237100
What this trial is testing

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Who this might be right for
Advanced Unresectable MelanomaMetastatic Melanoma
Kevin Kim, MD 10
Not applicableNot Yet RecruitingNCT07689812
What this trial is testing

Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Carcinoma)+12 more
Natera, Inc. 920
Testing effectiveness (Phase 2)Active Not RecruitingNCT04639219
What this trial is testing

T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations

Who this might be right for
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
AstraZeneca 102
Early research (Phase 1)Active Not RecruitingNCT04328844
What this trial is testing

Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

Who this might be right for
Solid Tumor, AdultNon-Hodgkin Lymphoma, AdultNSCLC+2 more
iOnctura 210
Testing effectiveness (Phase 2)Study completedNCT00911443
What this trial is testing

Thymosin Alpha 1, Interferon Alpha, or Both, in Combination With Dacarbazine in Patients With Malignant Melanoma

Who this might be right for
Malignant Melanoma
sigma-tau i.f.r. S.p.A. 488
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Testing effectiveness (Phase 2)Study completedNCT01134250
What this trial is testing

Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients

Who this might be right for
Solid TumorBreast CancerMetastatic Melanoma+1 more
Philogen S.p.A. 48
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