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Results for “Advanced Microsatellite Stable Colorectal Cancer”

69 trials

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Showing 20 of 69 results

Large-scale testing (Phase 3)Looking for participantsNCT05768503
What this trial is testing

Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 176
Early research (Phase 1)Active Not RecruitingNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Looking for participantsNCT04895709
What this trial is testing

BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more
Bristol-Myers Squibb 1,109
Not applicableStudy completedNCT03699111
What this trial is testing

Identification of New Patient Stratification Tools in MSS RAS mt mCRC

Who this might be right for
Advanced Colorectal Cancer
Cancer Trials Ireland 29
Testing effectiveness (Phase 2)UnknownNCT05307198
What this trial is testing

Rectal Artery Infusion Chemotherapy Combined With Anti-PD1 Antibody for MSS LARC

Who this might be right for
Rectal Neoplasms
Second Affiliated Hospital, School of Medicine, Zhejiang University 38
Testing effectiveness (Phase 2)Looking for participantsNCT06204094
What this trial is testing

Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Jinhua Central Hospital 37
Testing effectiveness (Phase 2)WithdrawnNCT06575725
What this trial is testing

Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaAdvanced Colorectal AdenocarcinomaAdvanced Rectal Adenocarcinoma+9 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381400
What this trial is testing

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

Who this might be right for
Rectal Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 128
Testing effectiveness (Phase 2)Looking for participantsNCT05136326
What this trial is testing

Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer

Who this might be right for
Rectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 21
Early research (Phase 1)Ended earlyNCT06546553
What this trial is testing

Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Who this might be right for
NeoplasmsNon-small-cell Lung CancerSquamous Cell Carcinoma of the Head and Neck+3 more
Pfizer 10
Testing effectiveness (Phase 2)Study completedNCT04895137
What this trial is testing

MFOLFOX6+Bevacizumab+PD-1 Monoclonal Antibody in Local Advanced MSS CRC

Who this might be right for
Colorectal CancerImmunotherapy
Sixth Affiliated Hospital, Sun Yat-sen University 42
Testing effectiveness (Phase 2)Looking for participantsNCT07527858
What this trial is testing

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal Cancer
Gilead Sciences 170
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Early research (Phase 1)Not Yet RecruitingNCT07363408
What this trial is testing

Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+1 more
City of Hope Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05691491
What this trial is testing

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Who this might be right for
Advanced Malignant Solid NeoplasmAdvanced Microsatellite Stable Colorectal CarcinomaHematopoietic and Lymphatic System Neoplasm+4 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)UnknownNCT03946917
What this trial is testing

JS001 Combined With Regorafenib in Patients With Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 44
Testing effectiveness (Phase 2)Ended earlyNCT02959437
What this trial is testing

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Who this might be right for
Solid TumorsAdvanced MalignanciesMetastatic Cancer
Incyte Corporation 70
Testing effectiveness (Phase 2)Study completedNCT04332653
What this trial is testing

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Who this might be right for
Any Advanced Solid TumorsTriple Negative Breast CancerNon Small Cell Lung Cancer+4 more
NeoImmuneTech 215
Testing effectiveness (Phase 2)Ended earlyNCT05733611
What this trial is testing

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Replimune, Inc. 5
Post-approval studies (Phase 4)Not Yet RecruitingNCT07446465
What this trial is testing

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer (Locally Advanced or Metastatic)Colorectal Cancer Microsatellite Stable (MSS)
Ye Xu 42
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