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Results for “Advanced Microsatellite Stable Colorectal Carcinoma”

52 trials

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Showing 20 of 52 results

Testing effectiveness (Phase 2)Ended earlyNCT05716295
What this trial is testing

A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Medikine, Inc. 26
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Ended earlyNCT02959437
What this trial is testing

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Who this might be right for
Solid TumorsAdvanced MalignanciesMetastatic Cancer
Incyte Corporation 70
Early research (Phase 1)Active Not RecruitingNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Early research (Phase 1)Study completedNCT04943900
What this trial is testing

BMS-986416 With and Without Nivolumab in Select Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 67
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Early research (Phase 1)Study completedNCT02512172
What this trial is testing

Enhancing Response to MK-3475 in Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 27
Early research (Phase 1)Looking for participantsNCT05107674
What this trial is testing

NX-1607 in Adults With Advanced Malignancies

Who this might be right for
Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more
Nurix Therapeutics, Inc. 345
Early research (Phase 1)Ended earlyNCT04301011
What this trial is testing

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors

Who this might be right for
Solid TumorMicrosatellite Stable Colorectal CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+6 more
Turnstone Biologics, Corp. 27
Testing effectiveness (Phase 2)Ended earlyNCT05733611
What this trial is testing

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Replimune Inc. 5
Early research (Phase 1)Active Not RecruitingNCT04354246
What this trial is testing

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Who this might be right for
Advanced CancerOvarian CancerLung Cancer+6 more
Compugen Ltd 110
Early research (Phase 1)Looking for participantsNCT06444815
What this trial is testing

VET3-TGI in Patients With Solid Tumors

Who this might be right for
Solid Tumor, AdultMicrosatellite Stable Colorectal CancerHead and Neck Squamous Cell Carcinoma+7 more
KaliVir Immunotherapeutics 60
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Testing effectiveness (Phase 2)UnknownNCT04110093
What this trial is testing

Regorafenib Plus PD-1 Inhibitor in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerImmunotherapy
Shanghai Changzheng Hospital 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05359393
What this trial is testing

A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis

Who this might be right for
Advanced Rectal CancerLiver MetastasisPulmonary Metastasis+1 more
Fudan University 52
Testing effectiveness (Phase 2)Looking for participantsNCT06218810
What this trial is testing

Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerMicrosatellite Stable Colorectal CarcinomaRAS Mutation+1 more
Fudan University 53
Testing effectiveness (Phase 2)Looking for participantsNCT04977453
What this trial is testing

GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Cancer+11 more
GI Innovation, Inc. 430
Early research (Phase 1)Ended earlyNCT03549000
What this trial is testing

A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Triple Negative Breast Cancer (TNBC)Pancreatic Ductal Adenocarcinoma (PDAC)+4 more
Novartis Pharmaceuticals 127
Not applicableNot Yet RecruitingNCT06682247
What this trial is testing

A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Feng Wang 200
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
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