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Results for “Advanced Microsatellite Stable Colorectal Carcinoma”

57 trials

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Showing 20 of 57 results

Large-scale testing (Phase 3)Looking for participantsNCT05768503
What this trial is testing

Comparing Chidamide+Sintilimab+Bev With Standard Second-line FOLFIRI+Bev in Advanced MSS/pMMR mCRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 176
Testing effectiveness (Phase 2)Looking for participantsNCT04895709
What this trial is testing

BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more
Bristol-Myers Squibb 1,109
Testing effectiveness (Phase 2)UnknownNCT03946917
What this trial is testing

JS001 Combined With Regorafenib in Patients With Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT05672316
What this trial is testing

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

Who this might be right for
Advanced Colorectal AdenocarcinomaAdvanced Microsatellite Stable Colorectal CarcinomaMetastatic Colorectal Adenocarcinoma+3 more
City of Hope Medical Center 28
Early research (Phase 1)Study completedNCT04943900
What this trial is testing

BMS-986416 With and Without Nivolumab in Select Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 67
Testing effectiveness (Phase 2)Ended earlyNCT05716295
What this trial is testing

A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Medikine, Inc. 26
Early research (Phase 1)Looking for participantsNCT07540572
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Who this might be right for
ER+, HER 2- Breast CancerNon-small Cell Lung Cancer (NSCLC)Castration-resistant Prostate Cancer (CRPC)+1 more
IDEAYA Biosciences 160
Testing effectiveness (Phase 2)UnknownNCT04110093
What this trial is testing

Regorafenib Plus PD-1 Inhibitor in Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerImmunotherapy
Shanghai Changzheng Hospital 120
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)WithdrawnNCT06575725
What this trial is testing

Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaAdvanced Colorectal AdenocarcinomaAdvanced Rectal Adenocarcinoma+9 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Looking for participantsNCT05691491
What this trial is testing

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Who this might be right for
Advanced Malignant Solid NeoplasmAdvanced Microsatellite Stable Colorectal CarcinomaHematopoietic and Lymphatic System Neoplasm+4 more
National Cancer Institute (NCI) 42
Testing effectiveness (Phase 2)Looking for participantsNCT06218810
What this trial is testing

Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerMicrosatellite Stable Colorectal CarcinomaRAS Mutation+1 more
Fudan University 53
Testing effectiveness (Phase 2)Study completedNCT03473925
What this trial is testing

Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034)

Who this might be right for
Solid TumorsNon-small Cell Lung CancerCastration Resistant Prostate Cancer+1 more
Merck Sharp & Dohme LLC 107
Early research (Phase 1)UnknownNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Early research (Phase 1)UnknownNCT04326296
What this trial is testing

The Safety and Tolerability of PD-L1 Monoclonal Antibody Plus Lenalidomide in The Treatment of Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
LiNing 33
Testing effectiveness (Phase 2)Looking for participantsNCT06634875
What this trial is testing

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

Who this might be right for
Colorectal Cancer Metastatic
Buzzard Pharmaceuticals 20
Early research (Phase 1)Study completedNCT04362839
What this trial is testing

Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaMetastatic Colon AdenocarcinomaMetastatic Colorectal Adenocarcinoma+22 more
City of Hope Medical Center 39
Very early researchNot Yet RecruitingNCT07486492
What this trial is testing

Using Healthy Gut Bacteria to Boost Immune Treatment for Advanced Bowel Cancer

Who this might be right for
Colorectal Cancer MetastaticFecal Microbiota Transplantation
The First Affiliated Hospital of Xiamen University 10
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
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