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Results for “Advanced Myelodysplastic Syndrome”

181 trials

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Showing 20 of 181 results

Early research (Phase 1)Study completedNCT00351975
What this trial is testing

Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases

Who this might be right for
Accelerated Phase of DiseaseAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11+17 more
National Cancer Institute (NCI) 56
Testing effectiveness (Phase 2)Study completedNCT00724009
What this trial is testing

Clofarabine Bone Marrow Cytoreduction

Who this might be right for
Leukemia
University of Chicago 29
Testing effectiveness (Phase 2)Study completedNCT02639559
What this trial is testing

Safety and Efficacy of BL-8040 for the Mobilization of Donor Hematopoietic Stem Cells and Allogeneic Transplantation in Patients With Advanced Hematological Malignancies

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+8 more
Washington University School of Medicine 50
Early research (Phase 1)Active Not RecruitingNCT04013685
What this trial is testing

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoid LeukemiaMyelodysplastic Syndromes+3 more
Orca Biosystems, Inc. 155
Early research (Phase 1)Study completedNCT01139151
What this trial is testing

4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 31
Early research (Phase 1)Looking for participantsNCT05342584
What this trial is testing

Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Montefiore Medical Center 99
Testing effectiveness (Phase 2)Study completedNCT03047993
What this trial is testing

Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Multilineage DysplasiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsBlasts 20-30 Percent of Peripheral Blood White Cells+4 more
M.D. Anderson Cancer Center 28
Testing effectiveness (Phase 2)Ended earlyNCT02587598
What this trial is testing

Study of INCB053914 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 97
Early research (Phase 1)Ended earlyNCT00589316
What this trial is testing

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+7 more
Fred Hutchinson Cancer Center
Early research (Phase 1)Study completedNCT00602693
What this trial is testing

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma+2 more
Masonic Cancer Center, University of Minnesota 41
Testing effectiveness (Phase 2)Ended earlyNCT02089230
What this trial is testing

MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 19
Testing effectiveness (Phase 2)Study completedNCT02842827
What this trial is testing

Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New Jersey USA) 45
Early research (Phase 1)Active Not RecruitingNCT05455294
What this trial is testing

Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms

Who this might be right for
Myeloid MalignancyMyelodysplastic SyndromesMyelofibrosis+2 more
Jacqueline Garcia, MD 16
Early research (Phase 1)Active Not RecruitingNCT02530034
What this trial is testing

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveHematopoietic and Lymphoid Cell Neoplasm+8 more
M.D. Anderson Cancer Center 72
Not applicableStudy completedNCT00809367
What this trial is testing

Collection and Banking of Leukemia Cells MDS/AML

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid Leukemia
Dana-Farber Cancer Institute 90
Early research (Phase 1)Ended earlyNCT00676728
What this trial is testing

The Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic Syndrome

Who this might be right for
Advanced or Refractory LeukemiaMyelodysplastic Syndromes
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 10
Testing effectiveness (Phase 2)Study completedNCT00629798
What this trial is testing

Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid LeukemiaAdvanced Myelodysplastic Syndromes
Memorial Sloan Kettering Cancer Center 64
Early research (Phase 1)Study completedNCT02203825
What this trial is testing

Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-Ligands

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMultiple Myeloma
Celyad Oncology SA 12
Early research (Phase 1)Study completedNCT00005593
What this trial is testing

Fludarabine, Carboplatin, and Topotecan in Treating Patients With Relapsed/Refractory Acute Leukemia or Advanced Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic Syndromes
Case Comprehensive Cancer Center 31
Early research (Phase 1)Ended earlyNCT03404726
What this trial is testing

Investigate BAY2402234, a Dihydroorotate Dehydrogenase (DHODH) Inhibitor, in Myeloid Malignancies

Who this might be right for
Leukemia
Bayer 40
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