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Results for “Advanced Myeloproliferative Neoplasms”

166 trials

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Showing 20 of 166 results

Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Early research (Phase 1)Active Not RecruitingNCT04328844
What this trial is testing

Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers

Who this might be right for
Solid Tumor, AdultNon-Hodgkin Lymphoma, AdultNSCLC+2 more
iOnctura 210
Testing effectiveness (Phase 2)Looking for participantsNCT04996875
What this trial is testing

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Who this might be right for
Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc. 140
Testing effectiveness (Phase 2)Study completedNCT00724009
What this trial is testing

Clofarabine Bone Marrow Cytoreduction

Who this might be right for
Leukemia
University of Chicago 29
Early research (Phase 1)Looking for participantsNCT05088356
What this trial is testing

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Who this might be right for
Allogeneic Hematopoietic Cell Transplantation (HCT)Advanced Hematologic MalignanciesAcute Leukemia+3 more
Stanford University 60
Early research (Phase 1)Ended earlyNCT00943293
What this trial is testing

Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies

Who this might be right for
PreleukemiaMyeloproliferative DisordersLymphoma+2 more
University of Chicago 1
Testing effectiveness (Phase 2)Looking for participantsNCT06597734
What this trial is testing

Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm

Who this might be right for
Chronic Myelomonocytic LeukemiaAdvanced Myeloproliferative NeoplasmsIDH1-mutated Higher-Risk Myelodysplastic Syndromes
M.D. Anderson Cancer Center 45
Testing effectiveness (Phase 2)Ended earlyNCT01773395
What this trial is testing

GVAX vs. Placebo for MDS/AML After Allo HSCT

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia
Dana-Farber Cancer Institute 123
Early research (Phase 1)Study completedNCT00004065
What this trial is testing

Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer

Who this might be right for
Bladder CancerBreast CancerColorectal Cancer+9 more
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01660607
What this trial is testing

Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T Cell

Who this might be right for
Myeloid Leukemia, ChronicAcute Myelogenous LeukemiaMyelodysplastic Syndromes (MDS)+6 more
Stanford University 68
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Early research (Phase 1)Looking for participantsNCT06950034
What this trial is testing

STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

Who this might be right for
Chronic Myelomonocytic LeukemiaChronic Myelomonocytic Leukemia (CMML)Chronic Myelomonocytic Leukemia-1+9 more
Solu Therapeutics, Inc 105
Testing effectiveness (Phase 2)UnknownNCT05376852
What this trial is testing

Decitabine and HQP1351-based Chemotherapy Regimen for the Treatment Advanced CML

Who this might be right for
Chronic Myeloid Leukemia in Myeloid Blast CrisisChronic Myeloid Leukaemia TransformationChronic Myeloid Leukemia - Accelerated Phase+1 more
Nanfang Hospital, Southern Medical University 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT00544115
What this trial is testing

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+5 more
City of Hope Medical Center 260
Testing effectiveness (Phase 2)Study completedNCT01606579
What this trial is testing

Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myeloid Leukemia
Prism Pharma Co., Ltd. 49
Early research (Phase 1)Study completedNCT00038051
What this trial is testing

Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyeloproliferative Disorders+1 more
M.D. Anderson Cancer Center 28
Testing effectiveness (Phase 2)Ended earlyNCT02010645
What this trial is testing

Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 6
Not applicableLooking for participantsNCT01758042
What this trial is testing

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

Who this might be right for
Chronic Kidney DiseaseAcute Myeloid Leukemia (AML)Acute Lymphoblastic Leukemia (ALL)+14 more
Massachusetts General Hospital 10
Testing effectiveness (Phase 2)Ended earlyNCT02440685
What this trial is testing

Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors

Who this might be right for
Lymphoma, Large B-Cell, DiffuseLymphoma, Mantle-CellLymphoma, Follicular+18 more
Asana BioSciences 51
Testing effectiveness (Phase 2)Study completedNCT02666950
What this trial is testing

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic Syndrome With Isolated Del(5q)Myelodysplastic/Myeloproliferative Neoplasm+3 more
Mayo Clinic 3
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